H. Kim

发表

Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer's Disease.

Jiyoun Lee, D. Jo, H. Hong, 2018, Journal of medicinal chemistry.

Synthesis of N,N',N"-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor.

Hyun-Ju Koh, Y. Suh, H. Kim, 2003, Bioorganic & medicinal chemistry letters.

Synthesis of 2-substituted-pyrrolidinethiourea derivatives and their antagonist effect on vanilloid receptor.

Y. Suh, H. Kim, Ji Yeon Choi, 2003, Bioorganic & medicinal chemistry letters.

6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE).

Jiyoun Lee, Y. Suh, H. Hong, 2015, Bioorganic & medicinal chemistry.

Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE).

Jeeyeon Lee, Hyun-Ju Park, Y. Suh, 2015, Bioorganic & medicinal chemistry.

Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer's Agents by Structure-Based Design.

S. J. Y. Macalino, M. Cui, Sun Choi, 2019, Journal of medicinal chemistry.

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region.

M. Cui, Sun Choi, Jiyoun Lee, 2018, Bioorganic & medicinal chemistry.

Corrigendum to “structure–activity relationship study of asiatic acid derivatives against beta amyloid (Aβ)-induced neurotoxicity” (Bioorg. Med. Chem. Lett. 2000, 10, 119)

I. Mook‐Jung, M. W. Jung, H. Kim, 2000 .

Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.

Jiyoun Lee, Heejin Ha, Jihyae Ann, 2021, European journal of medicinal chemistry.

Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE).

Hyun-Ju Park, Y. Suh, Kyeojin Kim, 2014, European journal of medicinal chemistry.

N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.

Ji-Min Kim, Attila Toth, Jiyoun Lee, 2003, Journal of medicinal chemistry.

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents.

Jin Kwan Kim, S. Shin, Kwang-Ok Lee, 2005, Journal of medicinal chemistry.

Heterocycle-linked phenylbenzyl amides as novel TRPV1 antagonists and their TRPV1 binding modes: constraint-induced enhancement of in vitro and in vivo activities.

Sun Choi, Jong-Wha Jung, S. Shin, 2013, Chemistry - An Asian Journal.

Silicon switch approach in TRPV1 antagonist MK-056 and its analogues.

Ji Eun Park, Y. Suh, H. Kim, 2010, Bioorganic & medicinal chemistry.

Biarylcarboxybenzamide derivatives as potent vanilloid receptor (VR1) antagonistic ligands.

Jin Kwan Kim, S. Shin, Hyun-Ju Koh, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists.

Jong-Wha Jung, Y. Suh, H. Kim, 2009, Bioorganic & medicinal chemistry.

Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors.

Hyun-Ju Park, Y. Suh, H. Hong, 2012, Journal of medicinal chemistry.

Asiaticoside mimetics as wound healing agent

Jae-Ho Park, E. Park, H. Kim, 1996 .

Structure–activity relationship study of asiatic acid derivatives against beta amyloid (Aβ)-induced neurotoxicity

I. Mook‐Jung, M. W. Jung, H. Kim, 2000 .

Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.

K. Jacobson, Zhang-Guo Gao, W. J. Choi, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90

So-Jung Park, Hyun-Ju Park, Ho-Yyoung Lee, 2015, Molecular Pharmacology.

Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.

Megan L. Peach, J. Deschamps, N. Colburn, 2008, Journal of medicinal chemistry.

Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects.

Jin Kwan Kim, Yong-Sil Lee, Y. Suh, 2003, Bioorganic & medicinal chemistry letters.

Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors.

M. Cui, Sun Choi, Heejin Ha, 2018, Bioorganic & medicinal chemistry.

Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.

M. Cui, Sun Choi, Jiyoun Lee, 2017, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease.

E. Roh, H. Kim, Young-Ho Kim, 2012, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists.

D. Kwon, Y. Suh, H. Kim, 2009, Bioorganic & medicinal chemistry.

N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands.

Jin Kwan Kim, Y. Suh, H. Kim, 2004, Bioorganic & medicinal chemistry letters.

N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.

Y. Suh, H. Kim, Hyeung‐geun Park, 2004, Bioorganic & medicinal chemistry letters.

Chain-branched acyclic phenethylthiocarbamates as vanilloid receptor antagonists.

Y. Suh, H. Kim, Hyeung‐geun Park, 2003, Bioorganic & medicinal chemistry letters.

Branched diacylglycerol-lactones as potent protein kinase C ligands and alpha-secretase activators.

S. Y. Kim, Jeewoo Lee, I. Mook‐Jung, 2006, Journal of medicinal chemistry.

Chain-branched 1,3-dibenzylthioureas as vanilloid receptor 1 antagonists.

Ju-Hyun Park, Y. Suh, H. Kim, 2004, Bioorganic & medicinal chemistry letters.