L. Elliott

发表

Evaluation of assay technologies for the identification of protein-Peptide interaction antagonists.

W. Fairbrother, K. Deshayes, S. Kadkhodayan, 2007, Assay and drug development technologies.

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Vishva M. Dixit, V. Dixit, J. Blankenship, 2007, Cell.

Case Studies of Minimizing Nonspecific Inhibitors in HTS Campaigns That Use Assay-Ready Plates

Robert Mintzer, Adam R. Johnson, Marya Liimatta, 2012, Journal of biomolecular screening.

Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.

S. Hymowitz, W. Fairbrother, K. Deshayes, 2009, ACS chemical biology.

A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo*

D. Banner, M. Ultsch, D. Sutherlin, 2005, Journal of Biological Chemistry.

Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

Zhaoyang Wen, Brigitte Maurer, Vickie Tsui, 2012, Journal of medicinal chemistry.

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

Vishva M Dixit, V. Dixit, J. Blankenship, 2007, Cell.

Nucleic Acid Capture Assay: A Novel High- Throuhgput Method for Direct Mrna Quantitation

L. Zheng, P. Tsai, J. Stephan, 2005 .

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

K. Das, G. Salvesen, W. Fairbrother, 2005, The Biochemical journal.

Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres.

C. Ly, W. Fairbrother, V. Tsui, 2010, Bioorganic & medicinal chemistry letters.

Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold.

Vickie Tsui, Frederick Cohen, Harvey Wong, 2009, Journal of medicinal chemistry.

Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).

M. Distefano, W. Fairbrother, K. Deshayes, 2003, Biochemistry.

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.

W. Fairbrother, K. Deshayes, K. Zobel, 2006, ACS chemical biology.