C. Boojamra

发表

Solid-Phase Synthesis of 1,4-Benzodiazepine-2,5-diones. Library Preparation and Demonstration of Synthesis Generality

J. Ellman, C. Boojamra, K. Burow, 1997 .

Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study.

M. Desai, R. Jordan, R. Mackman, 2015, Journal of medicinal chemistry.

Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131

K. White, N. Parkin, R. Mackman, 2007, Antimicrobial Agents and Chemotherapy.

Synthetic dihydropacidamycin antibiotics: a modified spectrum of activity for the pacidamycin class.

C. Boojamra, S. Hecker, V. Lee, 2003, Bioorganic & medicinal chemistry letters.

Stereochemical elucidation and total synthesis of dihydropacidamycin D, a semisynthetic pacidamycin.

R. Leger, C. Boojamra, S. Hecker, 2001, Journal of the American Chemical Society.

Intracellular Metabolism of the Nucleotide Prodrug GS-9131, a Potent Anti-Human Immunodeficiency Virus Agent

R. Mackman, T. Cihlar, K. Lin, 2007, Antimicrobial Agents and Chemotherapy.

Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.

R. Mackman, T. Cihlar, J. Douglas, 2008, Bioorganic & medicinal chemistry letters.

Design and Proﬁling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeﬁciency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131 (cid:1) †

K. White, N. Parkin, R. Mackman, 2008 .

Prodrug , GS-9131 Orally Bioavailable Phosphonoamidate Immunodeficiency Virus Type 1 , and Its Nucleoside-Resistant Variants of Human Nucleotide Analog Active against Design and Profiling of GS-9148 , a Novel

K. White, N. Parkin, R. Mackman, 2007 .

Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.

I. Shih, R. Mackman, A. Ray, 2013, Bioorganic & medicinal chemistry letters.

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.

M. Desai, R. Mackman, T. Cihlar, 2010, Bioorganic & medicinal chemistry.

Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.

M. Desai, James M. Chen, R. Mackman, 2009, Bioorganic & medicinal chemistry.

Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.

R. Mackman, T. Cihlar, J. Douglas, 2007, Bioorganic & medicinal chemistry.

Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.

R. Mackman, T. Cihlar, J. Douglas, 2008, Bioorganic & medicinal chemistry letters.

Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.

R. Mackman, T. Cihlar, J. Douglas, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.

R. Mackman, T. Cihlar, J. Douglas, 2008, Bioorganic & medicinal chemistry letters.

Functionalization of Nitrogen and Oxugen Containing Heterocycles by Mercury Photosensitized Dehydrodimerizations

Stephen H. Brown, R. Crabtree, C. Boojamra, 1989 .

Synthesis of beta-C-Glycosides of N-Acetylglucosamine via Keck Allylation Directed by Neighboring Phthalimide Groups.

C. Bertozzi, C. Boojamra, B. A. Roe, 1996, The Journal of organic chemistry.

Synthesis of β‐C‐Glycosides of N‐Acetylglucosamine via Keck Allylation Directed by Neighboring Phthalimide Groups.

C. Bertozzi, C. Boojamra, B. A. Roe, 1997 .

The synthesis of glycols by mercury-photosensitized alcohol dehydrodimerization

R. Crabtree, C. Boojamra, Jesse C. Lee, 1993 .

Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

K. White, Xiaohong Liu, M. Mcgrath, 2010, Journal of molecular biology.

Composes de phosphonate therapeutiques

James M. Chen, Xiaowu Chen, C. Boojamra, 2004 .

AN EXPEDIENT AND HIGH-YIELDING METHOD FOR THE SOLID-PHASE SYNTHESIS OF DIVERSE 1,4-BENZODIAZEPINE-2,5-DIONES

J. Ellman, C. Boojamra, K. Burow, 1995 .

Synthesis And Anti-Hiv Activity Of Cyclic Pyrimidine Phosphonomethoxy Nucleosides And Their Prodrugs: A Comparison Of Phosphonates And Corresponding Nucleosides

R. Mackman, T. Cihlar, J. Douglas, 2007, Nucleosides, nucleotides & nucleic acids.