K. Moriarty

发表

Comprehensive survey of combinatorial library synthesis: 2005.

J. Salvino, R. Dolle, B. Le Bourdonnec, 2006, Journal of combinatorial chemistry.

Stereoselective synthesis of (Z,E)-2-bromo-1,3-dienes via the palladium (O) catalyzed cross coupling reactions of 1,1-dibromoolefins and vinylboronic acids

W. Roush, K. Moriarty, Bradley B. Brown, 1990 .

Novel cytokine release inhibitors. Part I: Triterpenes.

A. Zilberstein, K. Moriarty, F. Huang, 1998, Bioorganic & medicinal chemistry letters.

Orally active indole N-oxide PDE4 inhibitors.

C. Hulme, R. Labaudinière, S. Djurić, 1998, Bioorganic & medicinal chemistry letters.

5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk).

R. DesJarlais, J. Woska, C. Cywin, 2008, Bioorganic & medicinal chemistry letters.

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).

B. Tomczuk, R. DesJarlais, D. Ryan, 2008, Bioorganic & medicinal chemistry letters.

Benzofuran based PDE4 inhibitors.

C. Hulme, J. Regan, S. Djurić, 1999, Bioorganic & medicinal chemistry.

Quaternary substituted PDE IV inhibitors II: the synthesis and in vitro evaluation of a novel series of gamma-lactams.

J. Mason, C. Hulme, R. Labaudinière, 1998, Bioorganic & medicinal chemistry letters.

Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists.

J. Chiba, M. Yokoyama, J. Baldwin, 2006, Bioorganic & medicinal chemistry.

The formation, crystal and molecular structures of bis(η5-indenyl)dicarbonyltitanium and bis(η5-indenyl)dicarbonylzirconium

J. Atwood, K. Moriarty, M. Rausch, 1987 .

The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: a new class of Aurora-A kinase inhibitors.

H. Koblish, A. Maroney, Dana L. Johnson, 2006, Bioorganic & medicinal chemistry letters.

Studies on the Synthesis of Nargenicin A1: Highly Stereoselective Synthesis of the Complete Carbon Framework via the Transannular Diels−Alder Reaction of an 18-Membered Macrolide

K. Koyama, W. Roush, M. Curtin, 1996 .

Isodicyclopentadienes and related molecules. 43. Stereochemical course of .pi.-face coordination to isodicyclopentadiene during formation of mixed titanocene and zirconocene dichloride complexes

R. Rogers, A. Rheingold, P. Meunier, 1989 .

Isodicyclopentadienes and related molecules. 44. Analysis of the .pi.-facial preference for complexation of a camphor-derived, enantiomerically pure cyclopentadienyl ligand to CpMCl2 fragments (M = Ti and Zr)

R. Rogers, J. Mckinney, L. Paquette, 1989 .

The formation and crystal and molecular structures of (η5-pentamethylcyclopentadienyl)(η5-cyclopentadienyl)dichloro-titanium, -zirconium and -hafnium

M. Benning, R. Rogers, K. Moriarty, 1985 .

Sequential Annulation in Molecular Construction. A Short, Stereocontrolled Synthesis of (±)‐Hirsutene

L. Paquette, K. Moriarty, C.-C. Shen, 1991 .

Enantioselective synthesis of the bottom half of chlorothricolide. 3. Studies of the steric directing group strategy for stereocontrol in intramolecular Diels-Alder reactions

J. Warmus, W. Roush, R. Riva, 1991 .

Synthesis and properties of optically active organomolybdenum compounds

K. Moriarty, M. Rausch, 1989 .

Rapid Three-Component Assembly of (±)-Hirsutene

L. Paquette, K. Moriarty, C.-C. Shen, 1990 .

(E)‐1‐Tri‐n‐butylstannyl‐2‐trimethylsilylethylene

K. Moriarty, 2001 .

Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist.

J. Chiba, M. Yokoyama, J. Baldwin, 2005, Bioorganic & medicinal chemistry letters.

Dicarbonylbis(η5‐Cyclopentadienyl) Complexes of Titanium, Zirconium, and Hafnium

J. Bercaw, K. Moriarty, M. Rausch, 2007 .

Synthetic, x-ray structural and photoluminescence studies on pentamethylcyclopentadienyl derivatives of lanthanum, cerium and praseodymium

J. Atwood, H. Brittain, K. Moriarty, 1986 .

High-performance liquid chromatography of homologous titanaindene complexes

P. Udén, K. Moriarty, D. J. Mazzo, 1983 .

Itk kinase inhibitors: initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead.

D. Ryan, G. Roth, M. Kashem, 2008, Bioorganic & medicinal chemistry letters.

Progress in the Development of Agents to Control the Cell Cycle

H. Koblish, K. Moriarty, J. Dana, 2007 .

Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.

B. Tomczuk, R. DesJarlais, J. Spurlino, 2006, Bioorganic & medicinal chemistry letters.

(E)-1-Trimethylsilyl-2-trimethylstannylethylene

K. Moriarty, 2001 .

Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity.

R. DesJarlais, B. Grasberger, C. Schubert, 2006, Archives of biochemistry and biophysics.

The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase.

Wei Li, Gulzar Ahmed, John Dodd, 2004, Journal of medicinal chemistry.

The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I.

C. Hulme, R. Labaudinière, S. Djurić, 1998, Bioorganic & medicinal chemistry letters.

4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist.

K. Moriarty, L. Mitchell, F. Huang, 1992, Journal of medicinal chemistry.

A novel series of [2-[methyl(2-phenethyl)amino]-2-oxoethyl] benzene-containing leukotriene B4 antagonists: initial structure-activity relationships.

K. Moriarty, G. Poli, R. Galemmo, 1996, Journal of Medicinal Chemistry.

Structure-activity relationships study of two series of leukotriene B4 antagonists: novel indolyl and naphthyl compounds substituted with a 2-[methyl(2-phenethyl)amino]-2-oxoethyl side chain.

K. Moriarty, G. Poli, R. Galemmo, 1996, Journal of Medicinal Chemistry.

Structure-Activity Relationships Study of Two Series of Leukotriene B4 Antagonists: Novel Indolyl and Naphthyl Compounds Substituted with a 2- (Methyl(2-phenethyl)amino)-2-oxoethyl Side Chain.

K. Moriarty, G. Poli, R. Galemmo, 1997 .

Isodicyclopentadienes and related molecules. Part 40. Stereocontrolled bifacial complexation of the isodicyclopentadienyl ligand to cyclopentadienyltitanium dichloride fragments

P. Meunier, L. Paquette, K. Moriarty, 1988 .

Isodicyclopentadienes and related molecules. 45. (1R)-(-)-Nopol as the source of an optically pure fused cyclopentadienyl ligand. Stereochemical course of complexation to cyclopentadienyltitanium and -zirconium dichloride fragments

R. Rogers, L. Paquette, K. Moriarty, 1989 .

Stereoselective formation from a (1S,5S)-(−)-verbenone-derived cyclopentadiene of dimeric and mixed titanium and zirconium dichloride complexes

R. Rogers, L. Paquette, K. Moriarty, 1989 .

Isodicyclopentadienes and Related Molecules. Part 46. Stereoselective Formation from a (1S,5S)-(-)-Verbenone-Derived Cyclopentadiene of Dimeric and Mixed Titanium and Zirconium Dichloride Complexes.

R. Rogers, L. Paquette, K. Moriarty, 1989 .

5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk).

R. DesJarlais, J. Woska, C. Cywin, 2008, Bioorganic & medicinal chemistry letters.