P. Feldman

发表

Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesterase.

J. Veal, F. Schoenen, J. Stafford, 1995, Journal of medicinal chemistry.

Chapter 8. Chronic Pulmonary Inflammation and Other Therapeutic Applications of PDE IV Inhibitors

J. Stafford, P. Feldman, 1996 .

Nitric oxide: a new paradigm for second messengers.

J. Lancaster, P. Feldman, J. Kerwin, 1995, Journal of medicinal chemistry.

An efficient and practical total synthesis of (+)-vincamine from L-aspartic acid

M. Chu-Moyer, P. Gmeiner, H. Rapoport, 1990 .

Insights into the Chemical Discovery of Remifentanil.

P. Feldman, 2020, Anesthesiology.

Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation.

O. Griffith, D. Stuehr, P. Feldman, 1993, Journal of medicinal chemistry.

CNS 7056: A Novel Ultra–short-acting Benzodiazepine

Gavin Kilpatrick, J. Stafford, G. J. Pacofsky, 2007, Anesthesiology.

Quality guidelines for oral drug candidates: dose, solubility and lipophilicity.

P. Leeson, D. Green, M. Bayliss, 2016, Drug discovery today.

A novel one-pot synthesis of N-substituted thieno[3,2-d]pyrimidin-4(3H) -ones

P. Feldman, A. Peat, Dulce M Garrido, 2006 .

Rapid synthesis of novel dipeptide inhibitors of human collagenase and gelatinase using solid phase chemistry

M. Lambert, M. Foley, D. Drewry, 1996 .

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.

Potent dipeptide inhibitors of the pp60c-src SH2 domain.

P. Charifson, K. Lackey, L. Shewchuk, 1998, Journal of medicinal chemistry.

Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.

D. Stuehr, P. Feldman, H. Abu-Soud, 1994, The Journal of biological chemistry.

Mercury vapor control by means of corona discharge

P. Feldman, G. Harmon, D. Helfritch, 1996 .

Synthesis of optically pure .DELTA.4-tetrahydroquinolinic acids and hexahydroindolo[2,3-a]quinolizines from L-aspartic acid. Racemization on the route to vindoline

H. Rapoport, P. Feldman, 1986 .

A 28-Day Toxicity Study of Tenofovir Alafenamide Hemifumarate by Subcutaneous Infusion in Rats and Dogs

S. Roller, P. Feldman, Bing Yang, 2021, Microbiology spectrum.

Synthesis of ultra-short-acting neuromuscular blocker GW 0430: a remarkably stereo- and regioselective synthesis of mixed tetrahydroisoquinolinium chlorofumarates.

J. A. Ray, R. Mook, V. Samano, 1999, Organic letters.

Tenofovir Alafenamide for HIV Prevention: Review of the Proceedings from the Gates Foundation Long-Acting TAF Product Development Meeting

A. van der Straten, T. Hope, R. Veazey, 2021, AIDS research and human retroviruses.

An efficient and mild synthesis of highly substituted imidazoles

J. Stafford, M. Brackeen, P. Feldman, 1994 .

Intramolecular nitrogen-hydrogen, oxygen-hydrogen and sulfur-hydrogen insertion reactions. Synthesis of heterocycles from .alpha.-diazo .beta.-keto esters

H. Rapoport, P. Feldman, M. Moyer, 1985 .

Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists.

J. Stafford, G. J. Pacofsky, P. Feldman, 2002, Bioorganic & medicinal chemistry letters.

Identification and structure-activity studies of novel ultrashort-acting benzodiazepine receptor agonists.

J. Stafford, G. J. Pacofsky, P. Feldman, 2002, Bioorganic & medicinal chemistry letters.

Stereoselective synthesis and absolute stereochemistry of sinefungin

M. Maguire, H. Rapoport, P. Feldman, 1990 .

The surprising life of nitric oxide

O. Griffith, D. Stuehr, P. Feldman, 1993 .

Ketenes. 20. Thermal decomposition of 2,2,6-trimethyl-4H-1,3-dioxin-4-one and 1-ethoxybutyn-3-one. Acetylketene

P. Feldman, R. Clemens, J. Hyatt, 1984 .

Convenient Synthesis of 6-Methoxyindole and 6-Methoxytryptophyl Bromide

H. Rapoport, P. Feldman, 1986 .

Intramolecular N-H, O-H and S-H Insertion Reactions. Synthesis of Heterocycles from α-Diazo β-Keto Esters.

H. Rapoport, P. Feldman, M. Moyer, 1986 .

Stereocontrolled synthesis of cis-dibenzoquinolizine chlorofumarates: curare-like agents of ultrashort duration.

J. A. Ray, R. Mook, A. Sefler, 2001, The Journal of organic chemistry.

Degradative Rearrangements of N-(t-Butyloxycarbonyl)-O-methanesulfonyl-hydroxamic Acids: A Novel, Reagent-Based Alternative to the Lossen Rearrangement1

J. Stafford, P. Feldman, Stephen S. Gonzales, 1998 .

Benzodiazepines a action breve

J. Stafford, G. J. Pacofsky, P. Feldman, 2000 .

Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1.

M. J. Bishop, A. Goetz, F. Tavares, 2006, Journal of medicinal chemistry.

Synthesis of (-)-vindoline

H. Rapoport, P. Feldman, 1987 .

Synthesis of (‐)‐Vindoline.

H. Rapoport, P. Feldman, 1987 .

Control of electron transfer in neuronal nitric oxide synthase by calmodulin, substrate, substrate analogs, and nitric oxide.

D. Rousseau, D. Stuehr, P. Feldman, 1995, Advances in pharmacology.

The formation of a covalent complex between a dipeptide ligand and the src SH2 domain.

P. Charifson, L. Shewchuk, W. Rocque, 1998, Bioorganic & medicinal chemistry letters.

Phosphodiesterase type IV (PDE IV) inhibition. Synthesis and evaluation of a series of 1,3,4-trisubstituted pyrrolidines

J. Stafford, D. Cowan, P. Domanico, 1995 .

Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics.

M. K. James, M. Johnson, M W Lutz, 1991, Journal of medicinal chemistry.

Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues.

M. K. James, M. Brackeen, P. Feldman, 1991, The Journal of pharmacology and experimental therapeutics.

Preclinical Pharmacology of GW280430A (AV430A) in the Rhesus Monkey and in the Cat: A Comparison with Mivacurium

Sanjay S. Patel, R. Mook, T. Spitzer, 2004, Anesthesiology.

Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys.

Sanjay S. Patel, J. A. Ray, R. Mook, 2003, Journal of medicinal chemistry.

Bis- and mixed-tetrahydroisoquinolinium chlorofumarates: new ultra-short-acting nondepolarizing neuromuscular blockers.

J. A. Ray, R. Mook, V. Samano, 1999, Journal of medicinal chemistry.

N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.

C. Nathan, N. Kwon, O. Griffith, 1991, The Journal of biological chemistry.

Development and Regulatory Challenges for Peptide Therapeutics

Jessica J. Hawes, T. Sawyer, P. Feldman, 2020, International journal of toxicology.

6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.

M. J. Bishop, A. Goetz, F. Tavares, 2006, Journal of medicinal chemistry.

Phosphodiesterase type IV inhibition. Structure-activity relationships of 1,3-disubstituted pyrrolidines.

F. Schoenen, J. Stafford, M. A. Leesnitzer, 1995, Journal of medicinal chemistry.

Electrode life of aluminium resistance spot welding in automotive applications: a survey

P. Feldman, W. Zhang, S. Rama, 2017 .

Sterilization and plasma processing of room temperature surfaces with a one atmosphere uniform glow discharge plasma (OAUGDP)

Zhenxiang Chen, Peter Ping-yi Tsai, F. Karakaya, 2000 .

Gut Hormone Pharmacology of a Novel GPR119 Agonist (GSK1292263), Metformin, and Sitagliptin in Type 2 Diabetes Mellitus: Results from Two Randomized Studies

L. Corsino, D. Nunez, M. Bush, 2014, PloS one.

Synthesis of the putative l-arginine metabolite L-NG-hydroxyarginine

P. Feldman, 1991 .

A novel route to the 4-anilido-4-(methoxycarbonyl)piperidine class of analgetics

M. Brackeen, P. Feldman, 1990 .

A Novel Route to the 4-Anilido-4-(methoxycarbonyl)piperidine Class of Analgetics.

M. Brackeen, P. Feldman, 1990 .

Mechanisms of Mammalian Nitric Oxide Biosynthesis

O. Griffith, D. Stuehr, J. Fukuto, 1995 .

Peracid oxidation of an N-hydroxyguanidine compound: a chemical model for the oxidation of N omega-hydroxyl-L-arginine by nitric oxide synthase.

M. Bova, D. Stuehr, J. Fukuto, 1993, Journal of medicinal chemistry.

Recent Progress in the Discovery of New CCR5 and CXCR4 Chemokine Receptor Antagonists as Inhibitors of HIV-1 Entry. Part 2*

Stephen Jenkinson, S. Piscitelli, W. Kazmierski, 2005 .

A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesics.

M. K. James, J. Pressley, M. Brackeen, 1994, The Journal of pharmacology and experimental therapeutics.

Synthesis of the L-arginine congener L-indospicine and evaluation of its interaction with nitric oxide synthase

D. Stuehr, P. Feldman, S. Chi, 1996 .

Structure-activity relationships involving the catechol subunit of rolipram

F. Schoenen, J. Stafford, P. Domanico, 1994 .

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.

Nitric Oxide: A New Paradigm for Second Messengers

J. Lancaster, P. Feldman, J. Kerwin, 1996 .