P. Pasau

发表

Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines

S. Ley, D. N. Tran, Jian-Siang Poh, 2017, Angewandte Chemie.

Radical C–H 18F-Difluoromethylation of Heteroarenes with [18F]Difluoromethyl Heteroaryl-Sulfones by Visible Light Photoredox Catalysis

A. Luxen, C. Lemaire, Agostinho Lemos, 2020, Catalysts.

Late‐Stage 18 F‐Difluoromethyl Labeling of N‐Heteroaromatics with High Molar Activity for PET Imaging

A. Luxen, C. Lemaire, Agostinho Lemos, 2019, Angewandte Chemie.

Late‐Stage 18F‐Difluoromethyl Labeling of N‐Heteroaromatics with High Molar Activity for PET Imaging

A. Luxen, C. Lemaire, Agostinho Lemos, 2019, Angewandte Chemie.

Dual NK1 Antagonists—Serotonin Reuptake Inhibitors as Potential Antidepressants. Part 2. SAR and Activity of Benzyloxyphenethyl Piperazine Derivatives.

R. Grimée, Y. Lamberty, T. Ryckmans, 2003 .

First Dual NK1 Antagonists—Serotonin Reuptake Inhibitors: Synthesis and SAR of a New Class of Potential Antidepressants.

Y. Lamberty, T. Ryckmans, O. Berton, 2002 .

Scale-Up and Optimization of a Continuous Flow Carboxylation of N-Boc-4,4-difluoropiperidine Using s-BuLi in THF

J. Jacq, P. Pasau, J. Frost, 2021, Organic Process Research & Development.

Discovery of new C3aR ligands. Part 1: arginine derivatives.

T. Lewis, P. Pasau, P. Collart, 2007, Bioorganic & medicinal chemistry letters.

Multicomponent reactions for the synthesis of complex piperidine scaffolds.

E. Jnoff, P. Pasau, Wei Zhu, 2009, Angewandte Chemie.

Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity.

M. Gillard, P. Talaga, Bénédicte Lallemand, 2004, Journal of medicinal chemistry.

Three-Component Assembly of Multiply Substituted Homoallylic Alcohols and Amines Using a Flow Chemistry Photoreactor.

S. Ley, D. Blakemore, P. Pasau, 2018, Organic letters.

Development of a Flow Photochemical Aerobic Oxidation of Benzylic C-H Bonds.

P. Pasau, M. Lesieur, C. Genicot, 2018, Organic letters.

C-H functionalisation of aldehydes using light generated, non-stabilised diazo compounds in flow.

S. Ley, B. Musio, D. Blakemore, 2018, Chemical communications.

Direct sulfonylation of anilines mediated by visible light† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03891g

M. Maccoss, C. Schofield, M. Willis, 2017, Chemical science.

Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists.

M. Gillard, P. Pasau, T. Kogej, 2007, Bioorganic & medicinal chemistry letters.

C−H Cyanation of 6‐Ring N‐Containing Heteroaromatics

M. Maccoss, C. Schofield, M. Willis, 2017, Chemistry.

Stereoselective synthesis of methyl (1R) trans- and (1R) cis-hemicaronaldehydes from natural tartaric acid: Application to the synthesis of s-bioallethrin and deltamethrin insecticides§

P. Lecomte, P. Pasau, A. Krief, 1989 .

First dual NK(1) antagonists-serotonin reuptake inhibitors: synthesis and SAR of a new class of potential antidepressants.

Thomas Ryckmans, Patrick Pasau, Y. Lamberty, 2002, Bioorganic & medicinal chemistry letters.

Photochemical Homologation for the Preparation of Aliphatic Aldehydes in Flow.

S. Ley, D. Blakemore, M. Leonardi, 2018, The Journal of organic chemistry.

New synthetic pathway to diverse 2-substituted quinolines based on a multicomponent reaction: solution-phase and solid-phase applications.

P. Pasau, L. Knerr, Thierry Demaude, 2004, Journal of combinatorial chemistry.

Synthesis of Electron-Deficient Heteroaromatic 1,3-Substituted Cyclobutyls via Zinc Insertion/Negishi Coupling Sequence under Batch and Automated Flow Conditions.

P. Pasau, S. Petit, C. Genicot, 2018, Organic letters.

Trip Around the Three-Membered Cycles Syntheses

P. Lecomte, P. Pasau, A. Krief, 1989 .

Direct Oxidation of Csp3 -H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow.

S. Ley, J. Jacq, C. Battilocchio, 2018, Chemistry.

Discovery of orally bioavailable NK1 receptor antagonists.

T. Taverne, T. Ryckmans, L. Goossens, 2003, Bioorganic & medicinal chemistry letters.

A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl–Alkyl Cross‐Coupling Reactions

S. Ley, D. Blakemore, Jian-Siang Poh, 2017, Angewandte Chemie.

Dual NK(1) antagonists--serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives.

R. Grimée, Y. Lamberty, T. Ryckmans, 2002, Bioorganic & medicinal chemistry letters.

Novel results on the biocyclisation of 2,3-oxidosqualene analogs by sterol cyclase

E. Guittet, Yang Shan, P. Pasau, 1993 .

Comparison of the behavior of oxidosqualene cyclases from pig liver and yeast toward epoxy-squalene analogues possessing a Δ 18–19 Z or E C, C Double bond.

P. Pasau, A. Krief, L. Quéré, 1991 .

Discovery of new C3aR ligands. Part 2: amino-piperidine derivatives.

P. Pasau, P. Collart, J. Nicolas, 2007, Bioorganic & medicinal chemistry letters.

Development of a General Automated Flow Photoredox 18F-Difluoromethylation of N-Heteroaromatics in an AllinOne Synthesizer

A. Luxen, C. Lemaire, Agostinho Lemos, 2020 .

Multistep flow synthesis of 5-amino-2-aryl-2H-[1,2,3]-triazole-4-carbonitriles.

J. Jacq, P. Pasau, 2014, Chemistry.

Quantitative In Silico Prediction of the Rate of Protodeboronation by a Mechanistic Density Functional Theory-Aided Algorithm

J. Goodman, A. Lapkin, P. Pasau, 2023, The journal of physical chemistry. A.

Stereospecific Amination of Mesylated Cyclobutanol in Continuous Flow

J. Jacq, P. Pasau, M. Tissot, 2020, Organic Process Research & Development.

Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead

P. Higgins, J. Eckman, M. Gillard, 2007 .