J. Bonfanti

发表

Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship.

K. Andries, P. Timmerman, E. Arnoult, 2007, Journal of medicinal chemistry.

Antiviral and lung protective activity of a novel respiratory syncytial virus fusion inhibitor in a mouse model

D. Nauwelaers, P. V. Remoortere, D. Roymans, 2010, European Respiratory Journal.

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

Brigitte E. Sanders-Beer, B. Sanders-Beer, D. Roymans, 2015, PloS one.

Discovery of the RSV Inhibitor TMC353121

D. Roymans, G. Ispas, J. Bonfanti, 2011 .

1,5-Benzodiazepine inhibitors of HCV NS5B polymerase.

M. Cummings, Lili Hu, F. Pauwels, 2009, Bioorganic & medicinal chemistry letters.

Palladium catalyzed one-pot sequential Suzuki cross-coupling-direct C-H functionalization of imidazo[1,2-a]pyrazines.

P. Jubault, J. Bonfanti, C. Hoarau, 2012, Organic letters.

1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors

M. Cummings, F. Pauwels, O. Nyanguile, 2008, Antimicrobial Agents and Chemotherapy.

Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).

K. Andries, C. Meyer, P. Timmerman, 2008, Journal of medicinal chemistry.

Practical Synthesis of Ethyl 3-Fluoro-1-pyrrole-2-carboxylate: A Key Fragment of a Potent Drug Candidate against Hepatitis B Virus

X. Pannecoucke, P. Jubault, T. Poisson, 2020, Organic Process Research & Development.

Toward the Synthesis of Fluorinated Analogues of HCV NS3/4A Serine Protease Inhibitors Using Methyl α-Amino-β-fluoro-β-vinylcyclopropanecarboxylate as Key Intermediate.

X. Pannecoucke, P. Jubault, F. Andriessen, 2015, Organic letters.

Synthesis of fluorinated cyclopropyl amino acid analogues: toward the synthesis of original fluorinated peptidomimetics.

X. Pannecoucke, P. Jubault, J. Bonfanti, 2013, The Journal of organic chemistry.

Efficient Syntheses of Pure Mixed Triglycerides

J. Gras, J. Bonfanti, Jean-François Bonfanti, 2000 .

Development of a high-throughput antiviral assay for screening inhibitors of chikungunya virus and generation of drug-resistant mutations in cultured cells.

J. Bonfanti, B. Van Kerckhove, E. Gong, 2013, Methods in molecular biology.

From Oxetane to Thietane: Extending the Antiviral Spectrum of 2'-Spirocyclic Uridines by Substituting Oxygen with Sulfur.

J. Neefs, E. Jacoby, Peggy Geluykens, 2022, ACS medicinal chemistry letters.