M. Rouan

发表

Antiviral and lung protective activity of a novel respiratory syncytial virus fusion inhibitor in a mouse model

D. Nauwelaers, P. V. Remoortere, D. Roymans, 2010, European Respiratory Journal.

M. Rouan, 1985, Journal of chromatography.

Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.

M. Rouan, F. Abadie, A. Leclerc, 1983, Journal of chromatography.

Determination of cefsulodin, cefotiam, cephalexin, cefotaxime, desacetyl-cefotaxime, cefuroxime and cefroxadin in plasma and urine by high-performance liquid chromatography.

M. Rouan, F. Juge, J. Lecaillon, 1982, Journal of chromatography.

Pharmacokinetics and Pharmacodynamics of TMC207 and Its N-Desmethyl Metabolite in a Murine Model of Tuberculosis

K. Andries, N. Lounis, L. Dillen, 2011, Antimicrobial Agents and Chemotherapy.

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

Brigitte E. Sanders-Beer, B. Sanders-Beer, D. Roymans, 2015, PloS one.

Dose- and Time-dependency of the Toxicity and Pharmacokinetic Profiles of Bedaquiline and Its N-desmethyl Metabolite in Dogs

G. Mannens, T. Verhaeghe, M. Rouan, 2017, Toxicologic pathology.

Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.

M. Cummings, B. Devogelaere, Lili Hu, 2012, Bioorganic & medicinal chemistry letters.

Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection.

M. Rouan, P. Mangoni, G. Maurer, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.

M. Cummings, B. Devogelaere, Lili Hu, 2014, Journal of medicinal chemistry.

Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia.

R. Galanello, A. Piga, M. Rouan, 2003, Journal of clinical pharmacology.

Safety, Tolerability, and Pharmacokinetics of ICL670, a New Orally Active Iron‐Chelating Agent in Patients with Transfusion‐Dependent Iron Overload Due to β‐Thalassemia

R. Galanello, A. Piga, M. Rouan, 2003 .

Benzoxazole and benzothiazole amides as novel pharmacokinetic enhancers of HIV protease inhibitors.

T. Jonckers, J. Sasaki, M. Rouan, 2012, Bioorganic & medicinal chemistry letters.

Automated microanalysis of oxcarbazepine and its monohydroxy and transdiol metabolites in plasma by liquid chromatography.

M. Rouan, J. Godbillon, J. Lecaillon, 1994, Journal of chromatography. B, Biomedical applications.

Pharmacokinetics-Pharmacodynamics of a Respiratory Syncytial Virus Fusion Inhibitor in the Cotton Rat Model

D. Nauwelaers, D. Roymans, K. Andries, 2010, Antimicrobial Agents and Chemotherapy.

Automated analysis of a novel anti-epileptic compound, CGP 33,101, and its metabolite, CGP 47,292, in body fluids by high-performance liquid chromatography and liquid-solid extraction.

M. Rouan, J. Godbillon, J. Lecaillon, 1995, Journal of chromatography. B, Biomedical applications.

Microbore liquid chromatographic determination of cadralazine and cephalexin in plasma with large-volume injection.

M. Rouan, 1988, Journal of Chromatography A.

Pharmacokinetics of cefotiam in humans

M. Rouan, J. Schoeller, J. Lecaillon, 1985, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and dosage adjustment of cefotiam in renal impaired patients.

U. Binswanger, M. Rouan, W. Theobald, 1984, The Journal of antimicrobial chemotherapy.

SINGLE TREATMENT OF INVASIVE FASCIOLIASIS WITH TRICLABENDAZOLE

L. Loutan, M. Rouan, H. Stalder, 1989, The Lancet.

Sequestration pulmonaire; diagnostiquée par la tomographie.

M. Rouan, R. Camain., P. Barroux, 1958 .

Real life juvenile toxicity case studies: the good, the bad and the ugly.

L. D. De Zwart, T. P. Coogan, J. Monbaliu, 2008, Reproductive toxicology.

The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites

P. Jungers, J. Aldigier, M. Rouan, 2004, European Journal of Clinical Pharmacology.

Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties.

M. Cummings, B. Devogelaere, Lili Hu, 2012, Angewandte Chemie.

Co-administration of darunavir and a new pharmacokinetic booster: formulation strategies and evaluation in dogs.

Lieven Baert, Jody Voorspoels, Jan Rosier, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series.

M. Cummings, Lili Hu, O. Nyanguile, 2012, Bioorganic & medicinal chemistry letters.

Fully automated analytical system using liquid-solid extraction and liquid chromatography for the determination of CGP 6140 in plasma.

M. Rouan, J. Dubois, J. Lecaillon, 1988, Journal of Chromatography A.

Fast liquid chromatography for the determination of drugs in plasma and combination with liquid-solid extraction in a fully automated system.

M. Rouan, J. Godbillon, J. Lecaillon, 1992, Journal of chromatography.

Automated microanalysis of carbamazepine and its epoxide and trans-diol metabolites in plasma by column liquid chromatography.

M. Rouan, J. Godbillon, J. Lecaillon, 1992, Journal of chromatography.

Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties.

M. Cummings, B. Devogelaere, Lili Hu, 2012, Angewandte Chemie.

1188 COMBINATION THERAPY OF TMC647055 WITH SIMEPREVIR (TMC435) IN CHRONIC HEPATITIS C PATIENTS

P. V. Remoortere, S. Bourgeois, H. Reesink, 2013 .

Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.

M. Cummings, B. Devogelaere, Lili Hu, 2014, Journal of medicinal chemistry.