S. Akashi

发表

Innate recognition of lipopolysaccharide by Toll-like receptor 4/MD-2 and RP105/MD-1

Yoshinori Nagai, Hirotaka Ogata, Y. Nagai, 2000, Journal of endotoxin research.

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Yoshinori Nagai, Hirotaka Ogata, K. Fukudome, 1999, The Journal of experimental medicine.

Cutting Edge: Lipopolysaccharide Induces Physical Proximity Between CD14 and Toll-Like Receptor 4 (TLR4) Prior to Nuclear Translocation of NF-κB1

H. Petty, K. Miyake, S. Akashi, 2000, The Journal of Immunology.

Safflower polysaccharides activate the transcription factor NF-kappa B via Toll-like receptor 4 and induce cytokine production by macrophages.

T. Kataoka, Izuru Ando, K. Miyake, 2002, International immunopharmacology.

Toll-Like Receptor 4, But Not Toll-Like Receptor 2, Is a Signaling Receptor for Escherichia and Salmonella Lipopolysaccharides1

P. Godowski, R. Tapping, K. Miyake, 2000, The Journal of Immunology.

Human Gingival CD14+ Fibroblasts Primed with Gamma Interferon Increase Production of Interleukin-8 in Response to Lipopolysaccharide through Up-Regulation of Membrane CD14 and MyD88 mRNA Expression

S. Akira, M. Torii, O. Takeuchi, 2002, Infection and Immunity.

Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide from Porphyromonas gingivalis in Human Gingival Fibroblasts

K. Miyake, H. Yoshie, S. Akashi, 2000, Infection and Immunity.

Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B.

H. Petty, K. Miyake, S. Akashi, 2000, Journal of immunology.

Mechanism of Anticancer Host Response Induced by OK-432, a Streptococcal Preparation, Mediated by Phagocytosis and Toll-Like Receptor 4 Signaling

K. Miyake, S. Akashi, S. Ahmed, 2006, Journal of immunotherapy.

Bacterial lipopolysaccharide induces mRNA expression of an IkappaB MAIL through toll-like receptor 4.

M. Morimatsu, M. Saito, H. Kitamura, 2002, The Journal of veterinary medical science.

Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent OK-432.

S. Akira, O. Takeuchi, K. Miyake, 2003, Journal of the National Cancer Institute.

Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol

T. Yoshida, K. Miyake, M. Nishijima, 2001, Journal of endotoxin research.

Penta-acylated lipopolisaccharide binds to murine MD-2 but does not induce the oligomerization of TLR4 required for signal transduction.

K. Fukudome, N. Tsuneyoshi, M. Kimoto, 2006, Cellular immunology.

Shigella protein IpaH ( 9 . 8 ) is secreted from bacteria within mammalian cells and transported to the nucleus

Hirotaka, K. Fukase, Y. Nagai, 2002 .

Toll-Like Receptor 4 Mediates the Antitumor Host Response Induced by a 55-Kilodalton Protein Isolated from Aeginetia indica L., a Parasitic Plant

S. Akira, O. Takeuchi, K. Miyake, 2004, Clinical Diagnostic Laboratory Immunology.

Essential role of MD-2 in B-cell responses to lipopolysaccharide and Toll-like receptor 4 distribution

Y. Nagai, K. Miyake, S. Akashi, 2002, Journal of endotoxin research.

Possible Involvement of Toll-Like Receptor 4 in Endothelial Cell Activation of Larger Vessels in Response to Lipopolysaccharide

K. Miyake, K. Matsuura, N. Hijiya, 2002, Pathobiology.

Monocytic Cell Activation by Nonendotoxic Glycoprotein from Prevotella intermedia ATCC 25611 Is Mediated by Toll-Like Receptor 2

S. Akira, O. Takeuchi, T. Espevik, 2001, Infection and Immunity.

Synergistic Effect of Muramyldipeptide with Lipopolysaccharide or Lipoteichoic Acid To Induce Inflammatory Cytokines in Human Monocytic Cells in Culture

S. Akira, O. Takeuchi, S. Sugawara, 2001, Infection and Immunity.

Osamu Monocytic Cells in Culture Induce Inflammatory Cytokines in Human ToLipopolysaccharide or Lipoteichoic Acid Synergistic Effect of Muramyldipeptide with

S. Akira, O. Takeuchi, S. Sugawara, 2001 .

Receptor 4 Expression Down-Regulation of Surface Toll-Like Peritoneal Macrophages Correlates with Cutting Edge: Endotoxin Tolerance in Mouse

S. Akira, Shintaro Sato, T. Kawai, 2000 .

Translocation of NF-Toll-Like Receptor 4 ( TLR 4 ) Prior to Nuclear Physical Proximity Between CD 14 and Cutting Edge : Lipopolysaccharide Induces

K. Miyake, S. Akashi, Q. Jiang, 2000 .

Mouse Peritoneal Macrophages Toll-Like Receptor 4-MD2 Complex on Lipopolysaccharide Signaling Via the Cutting Edge : Cell Surface Expression and

K. Takeda, Y. Nagai, K. Miyake, 2000 .

The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

K. Rajewsky, A. Tarakhovsky, Y. Nagai, 2000, The Journal of experimental medicine.

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

S. Akira, T. Kitamura, Y. Iwakura, 2002, Nature Immunology.

Generation and functional characterization of a clonal murine periportal Kupffer cell line from H‐2Kb –tsA58 mice

R. Landmann, J. Pieters, Y. Adachi, 2003, Journal of leukocyte biology.

Saccharomyces cerevisiae‐ and Candida albicans‐Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14‐ and Toll‐Like Receptor 4‐Dependent Manner

E. Nemoto, H. Shimauchi, K. Shibata, 2002, Microbiology and immunology.

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages1

K. Takeda, Y. Nagai, K. Miyake, 2000, The Journal of Immunology.

Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2

K. Fukase, Y. Nagai, K. Miyake, 2003, The Journal of experimental medicine.

Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression1

S. Akira, Shintaro Sato, K. Takeda, 2000, The Journal of Immunology.

Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization.

Makiko Kobayashi, K. Fukase, Y. Nagai, 2004, International immunology.

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition.

K. Fukase, Y. Nagai, K. Miyake, 2001, International immunology.

The Radioprotective 105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes1

S. Akira, T. Kaisho, M. Matsumoto, 2005, The Journal of Immunology.

RP105 is associated with MD-1 and transmits an activation signal in human B cells.

Y. Narisawa, K. Miyake, M. Kimoto, 1998, Blood.

Human B Cells RP105 Is Associated With MD-1 and Transmits an Activation Signal in

Y. Narisawa, K. Miyake, M. Kimoto, 2013 .

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide.

Y. Iwakura, Y. Nagai, K. Miyake, 2002, Blood.

Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells

Y. Narisawa, K. Miyake, M. Kimoto, 1998 .

Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis.

P. Godowski, K. Miyake, H. Makino, 2004, Arthritis and rheumatism.

Micrococcus luteus Teichuronic Acids Activate Human and Murine Monocytic Cells in a CD14- and Toll-Like Receptor 4-Dependent Manner

K. Miyake, Y. Adachi, M. Nishijima, 2001, Infection and Immunity.

Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

K. Miyake, M. Kimoto, J. Kondo, 1998, Journal of immunology.

Its Expression Associated with RP 105 and Positively Regulates Mouse MD-1 , a Molecule That Is Physically

K. Miyake, M. Kimoto, J. Kondo, 1998 .

Mouse Toll-like Receptor 4·MD-2 Complex Mediates Lipopolysaccharide-mimetic Signal Transduction by Taxol*

T. Yoshida, K. Miyake, M. Nishijima, 2000, The Journal of Biological Chemistry.

Hypoxia Diminishes Toll-Like Receptor 4 Expression Through Reactive Oxygen Species Generated by Mitochondria in Endothelial Cells1

H. Kubo, Hidetada Sasaki, Satoshi Suzuki, 2002, The Journal of Immunology.

Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.

T. Kirikae, K. Fukudome, Y. Nagai, 2000, Biochemical and biophysical research communications.

Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell-surface components through the CD14/Toll-like receptor system.

J. Hatakeyama, S. Sugawara, S. Akashi, 2003, Oral microbiology and immunology.

Response to Microbial Membranes Links TLR2 and TLR4/MD-2 in Antibody The Radioprotective 105/MD-1 Complex

S. Akira, T. Kaisho, M. Matsumoto, 2005 .

Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling

K. Fukase, K. Miyake, S. Kusumoto, 2004, Journal of endotoxin research.

Cells Generated by Mitochondria in Endothelial Expression Through Reactive Oxygen Species Hypoxia Diminishes Toll-Like Receptor 4

H. Kubo, Hidetada Sasaki, Satoshi Suzuki, 2010 .

The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

K. Rajewsky, A. Tarakhovsky, Y. Nagai, 2000, The Journal of experimental medicine.