D. Polk

T. Koyama, E. Rudzinski, H. Correa, 2009, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

HELICOBACTER PYLORI REGULATES CELLULAR MIGRATION AND APOPTOSIS BY ACTIVATION OF PI3K SIGNALING

T. A. Nagy, M. Frey, D. Polk, 2010 .

NRG4-ErbB4 signaling represses proinflammatory macrophage activity

M. Washington, Michael Schumacher, M. Frey, 2021, American journal of physiology. Gastrointestinal and liver physiology.

Integrin (cid:2) 1 (cid:3) 1 Controls Reactive Oxygen Species Synthesis by Negatively Regulating Epidermal Growth Factor Receptor-Mediated Rac Activation (cid:1)

Xiwu Chen, A. Pozzi, Rebecca S. Dise, 2007 .

Improved growth and disease activity after intermittent administration of a defined formula diet in children with Crohn's disease.

D. Polk, J. Kerner, J. Hattner, 1992, JPEN. Journal of parenteral and enteral nutrition.

Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.

Xiwu Chen, A. Pozzi, R. Harris, 2007, Molecular and cellular biology.

ACELL December 46/6

W. Tong, D. Polk, Wei Tong, 1999 .

The Role of Decay-accelerating Factor as a Receptor for Helicobacter pylori and a Mediator of Gastric Inflammation*♦

R. Peek, A. Franco, J. Romero-Gallo, 2006, Journal of Biological Chemistry.

Production and Experimental ColitisCytokine Receptor in Macrophages Regulates Activation of the Epidermal Growth Factor

L. Kaer, Lihong V Wang, M. K. Washington, 2013 .

Microbiomes through the Looking Glass: What Do UC?

D. Polk, Cambrian Y. Liu, 2018, Cell host & microbe.

ErbB receptors and their growth factor ligands in pediatric intestinal inflammation

M. Frey, D. Polk, 2013, Pediatric Research.

Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes

H. Ford, A. Grishin, J. Upperman, 2012, PloS one.

Epidermal growth factor suppresses intestinal epithelial cell shedding through a MAPK-dependent pathway

C. Lien, A. Watson, L. C. Harnisch, 2017, Journal of Cell Science.

Recurrent Abdominal Pain: Symptom Subtypes Based on the Rome II Criteria for Pediatric Functional Gastrointestinal Disorders

D. Polk, L. Walker, J. Stutts, 2004, Journal of pediatric gastroenterology and nutrition.

Functional Analysis of the p40 and p75 Proteins from Lactobacillus casei BL23

V. Monedero, G. Pérez-Martínez, D. Polk, 2010, Journal of Molecular Microbiology and Biotechnology.

Predicting persistence of functional abdominal pain from childhood into young adulthood.

J. Garber, B. Saville, D. Polk, 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Shc is a substrate of the rat intestinal epidermal growth factor receptor tyrosine kinase.

D. Polk, 1995, Gastroenterology.

Ontogenic regulation of phospholipase C-γ1 activity and expression in the rat small intestine

D. Polk, 1994 .

Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice

M. Washington, D. Polk, Cambrian Y. Liu, 2018, Scientific Reports.

Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

Yan Shi, Lihong V Wang, Tianhui Hu, 2011, PloS one.

Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth.

M. Washington, T. Cover, R. Whitehead, 2007, Gastroenterology.

Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutrition.

S. Moore, R. Guerrant, L. Denson, 2011, American Journal of Physiology - Gastrointestinal and Liver Physiology.

Mucosal Restitution and Repair

M. Frey, D. Polk, 2012 .

A Lactobacillus rhamnosus GG-derived Soluble Protein, p40, Stimulates Ligand Release from Intestinal Epithelial Cells to Transactivate Epidermal Growth Factor Receptor*

P. Dempsey, E. Raines, Linshu Liu, 2013, The Journal of Biological Chemistry.

Cellular maps of gastrointestinal organs: getting the most from tissue clearing.

Cambrian Yangshao Liu, D Brent Polk, D. Polk, 2020, American journal of physiology. Gastrointestinal and liver physiology.

Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8(+) T Cells in Mice With Colitis.

M. Washington, D. Polk, Cambrian Y. Liu, 2015, Gastroenterology.

Regulation of apoptosis during homeostasis and disease in the intestinal epithelium.

D. Polk, K. Edelblum, Fang Yan, 2006, Inflammatory bowel diseases.

ERBB4 PROMOTES CYCLOOXYGENASE-2 EXPRESSION AND CELL SURVIVAL IN COLON EPITHELIAL CELLS

M. Frey, D. Polk, M. Mullane, 2010, Laboratory Investigation.

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.

M. Washington, T. Cover, Yan Shi, 2011, The Journal of clinical investigation.

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty

D. Warburton, R. Batra, G. Carraro, 2011, Cancer biology & therapy.

Activation of Peroxisome Proliferator-activated Receptor γ Suppresses Nuclear Factor κB-mediated Apoptosis Induced by Helicobacter pylori in Gastric Epithelial Cells*

Rajnish A. Gupta, R. Peek, R. DuBois, 2001, The Journal of Biological Chemistry.

TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells.

M. Frey, D. Polk, K. Edelblum, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration.

R. Whitehead, Rebecca S. Dise, M. Frey, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβ

M. Washington, A. Means, O. McDonald, 2021, Cellular and molecular gastroenterology and hepatology.

TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice

M. Washington, J. Bender, D. Polk, 2020, Cell reports.

Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes

R. Peek, F. He, D. Polk, 2018, Mucosal Immunology.

Neonatal Colonization of Mice with LGG Promotes Intestinal Development and Decreases Susceptibility to Colitis in Adulthood

M. Washington, R. Peek, Bangmao Wang, 2016, Mucosal Immunology.

Probiotics and Probiotic-Derived Functional Factors—Mechanistic Insights Into Applications for Intestinal Homeostasis

D. Polk, Fang Yan, F. Yan, 2020, Frontiers in Immunology.

Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis.

M. Washington, T. Cover, P. Dempsey, 2009, Gastroenterology.

Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution.

Rebecca S. Dise, M. Frey, D. Polk, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism.

R. Rao, D. Polk, Fang Yan, 2008, American journal of physiology. Gastrointestinal and liver physiology.

TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival.

P. Dempsey, R. Peek, M. Frey, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Epidermal growth factor receptor inhibits colitis-associated cancer in mice.

M. Washington, S. Mcelroy, D. Polk, 2012, The Journal of clinical investigation.

Anal skin-like epithelium mediates colonic wound healing

M. Washington, B. Simons, D. Polk, 2021, bioRxiv.

A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells

R. Peek, D. Polk, Yang Wang, 2016, Mucosal Immunology.

Shc is a substrate of the rat intestinal epidermal growth factor receptor tyrosine kinase.

D. Polk, 1995, Gastroenterology.

Redeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel disease.

D. Polk, Shivesh Punit, P. Dubé, 2015, American journal of physiology. Gastrointestinal and liver physiology.

NODing off and Ramping up.

D. Abbott, D. Polk, 2005, Inflammatory bowel diseases.

Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation.

Fang Yan, D Brent Polk, M. Washington, 2004, The Journal of clinical investigation.

Bacterial meningitis presenting with normal cerebrospinal fluid.

R. Steele, D. Polk, Brent D. Polk, 1987, The Pediatric infectious disease journal.

Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios

M. Rock, T. Koyama, H. Correa, 2012, Gut.

Activation of the Epidermal Growth Factor Receptor in Macrophages Regulates Cytokine Production and Experimental Colitis

M. Washington, Lihong V Wang, H. Cao, 2014, The Journal of Immunology.

Mycophenolate Mofetil-Related Enterocolitis and Weight Loss: A Pediatric Case Series

J. Pugh, S. Moore, T. Hunley, 2012, Case reports in pediatrics.

Cell density—dependent regulation of PLCγ1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC‐6)

G. Carpenter, D. Polk, G. McCollum, 1995 .

Epidermal Growth Factor-stimulated Intestinal Epithelial Cell Migration Requires Src Family Kinase-dependent p38 MAPK Signaling*

M. Frey, D. Polk, A. Golovin, 2004, Journal of Biological Chemistry.

Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage.

Kristie L. Rose, M. Washington, D. Morgan, 2014, Gastroenterology.

BASIC AND TRANSLATIONAL — ALIMENTARY TRACT Spermine Oxidase Mediates the Gastric Cancer Risk Associated With Helicobacter pylori CagA

A. Gobert, R. Peek, J. Romero-Gallo, 2011 .

Histopathology of Ulcerative Colitis in Initial Rectal Biopsy in Children

E. Montgomery, K. Washington, Y. Shyr, 2002, The American journal of surgical pathology.

Epidermal and hepatocyte growth factors stimulate chemotaxis in an intestinal epithelial cell line.

W. Tong, D. Polk, D. Brent Polk, 1999, American journal of physiology. Cell physiology.

Innovative and Emerging Technologies in GI Physiology and Disease Optical reconstruction of murine colorectal mucosa at cellular resolution

D. Polk, Cambrian Y. Liu, P. Dubé, 2015 .

Activation of Epidermal Growth Factor Receptor in Macrophages Mediates Feedback Inhibition of M2 Polarization and Gastrointestinal Tumor Cell Growth*

R. Peek, X. Hao, D. Polk, 2016, The Journal of Biological Chemistry.

Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells.

D. Polk, F. Yan, 2001, Cancer research.

TNFR1 Promotes Tumor Necrosis Factor-mediated Mouse Colon Epithelial Cell Survival through RAF Activation of NF-κB*

T. Koyama, S. Mcelroy, D. Polk, 2008, Journal of Biological Chemistry.

Recurrent necrotizing jejunitis in a child.

M. Hernanz-Schulman, D. Polk, W. Morgan, 1996, The Journal of pediatrics.

Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.

S. Mcelroy, M. Frey, D. Polk, 2008, American journal of physiology. Gastrointestinal and liver physiology.

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration

Rebecca S. Dise, M. Frey, D. Polk, 2006, The EMBO journal.

Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells.

R. Peek, R. DuBois, D. Polk, 2001, The Journal of biological chemistry.

Probiotics: progress toward novel therapies for intestinal diseases

D. Polk, Fang Yan, F. Yan, 2010, Current opinion in gastroenterology.

Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB.

M. Washington, M. Baccarini, T. Koyama, 2008, Gastroenterology.

Production of a Functional Factor, p40, by Lactobacillus rhamnosus GG Is Promoted by Intestinal Epithelial Cell-Secreted Extracellular Vesicles

R. Peek, J. Higginbotham, D. Polk, 2019, Infection and Immunity.

Lactobacillus rhamnosus GG: An Updated Strategy to Use Microbial Products to Promote Health.

D. Polk, Fang Yan, 2012, Functional food reviews.

In vivo visualization of pyloric mucosal hypertrophy in infants with hypertrophic pyloric stenosis: is there an etiologic role?

W. Neblett, M. Hernanz-Schulman, D. Polk, 2001, AJR. American journal of roentgenology.

Hypertrophied pyloric mucosa in patients with hypertrophic pyloric stenosis

M. Hernanz-Schulman, D. Polk, Joyce E. Johnson, 1998, Pediatric Radiology.

The antral nipple sign of pyloric mucosal prolapse: endoscopic correlation of a new sonographic observation in patients with pyloric stenosis.

W. Neblett, M. Hernanz-Schulman, M. Ambrosino, 1995, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity.

D. Polk, D. Brent Polk, 1998, Gastroenterology.

Probiotics as functional food in the treatment of diarrhea

D. Polk, Fang Yan, F. Yan, 2006, Current opinion in clinical nutrition and metabolic care.

Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis

W. Tong, Rebecca S. Dise, D. Polk, 2008, Proceedings of the National Academy of Sciences.

Intestinal Na+/H+ Exchanger Activity is Up-Regulated by Bowel Resection in the Weanling Rat

J. Barnard, F. Ghishan, D. Polk, 1993, Pediatric Research.

Disruption of NF-κB signalling by ancient microbial molecules: novel therapies of the future?

D. Polk, Fang Yan, 2010, Gut.

future? microbial molecules: novel therapies of the B signalling by ancient κ Disruption of NF-

D. Polk, Fang Yan, 2010 .