N. Casares

发表

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.

J. Prieto, B. Sangro, J. Lasarte, 2011, Journal of hepatology.

Inhibition of Macroautophagy Triggers Apoptosis

Philippe Dessen, Guido Kroemer, G. Kroemer, 2005, Molecular and Cellular Biology.

Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without Toxicity

S. Hervás-Stubbs, G. González-Sapienza, N. Casares, 2020, Biomedicines.

In Vitro and In Vivo Down-Regulation of Regulatory T Cell Activity with a Peptide Inhibitor of TGF-β11

J. Prieto, S. V. van Deventer, J. Lasarte, 2008, The Journal of Immunology.

Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.

S. Hervás-Stubbs, J. Lasarte, J. Riezu-Boj, 2017, Cancer research.

The many faces of regulatory T cells

I. Melero, N. Casares, L. Gil-Guerrero, 2007 .

Inhibitor of TGF-Regulatory T Cell Activity with a Peptide In Vitro and In Vivo Down-Regulation of Borrás

J. Prieto, S. V. Deventer, J. Lasarte, 2008 .

Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy

F. Prósper, Flor Navarro, S. Hervás-Stubbs, 2022, Oncoimmunology.

Evaluation of a Salmonella Strain Lacking the Secondary Messenger C-di-GMP and RpoS as a Live Oral Vaccine

S. Burgui, C. Gil, C. Solano, 2016, PloS one.

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis.

J. Prieto, C. Leclerc, J. Lasarte, 2010, Vaccine.

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides.

J. Prieto, J. Lasarte, P. Sarobe, 1999, International immunology.

Abnormal Priming of CD 4 T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E 1 Proteins

J. Prieto, J. Lasarte, P. Sarobe, 2002 .

Searching for Peptide Inhibitors of T Regulatory Cell Activity by Targeting Specific Domains of FOXP3 Transcription Factor

J. Oyarzábal, A. Pineda-Lucena, J. Lasarte, 2021, Biomedicines.

Pre-selection of PD-1+ Tumor-Infiltrating CD8+ T cells improves the efficacy of adoptive T-cell Therapy

Spain, S. Hervás-Stubbs, J. Lasarte, 2018 .

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation

J. Prieto, J. Oyarzábal, P. Coffer, 2015, The Journal of Immunology.

Immunomodulatory Properties of Carvone Inhalation and Its Effects on Contextual Fear Memory in Mice

O. Rabal, S. Hervás-Stubbs, J. Lasarte, 2018, Front. Immunol..

MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells

J. Lasarte, N. Casares, S. Inogés, 2016, Oncotarget.

Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin

J. Prieto, C. Leclerc, P. Berraondo, 2012, International journal of cancer.

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements.

J. Prieto, E. Huarte, J. Lasarte, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses.

J. Prieto, C. Leclerc, J. Lasarte, 2012, Vaccine.

TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity.

Flor Navarro, S. Hervás-Stubbs, J. Lasarte, 2021, Cancer letters.

Vaccine Efficacy in Mice Regulatory T Cell Activity and Improves A Peptide Inhibitor of FOXP3 Impairs

J. Prieto, J. Lasarte, J. Riezu-Boj, 2010 .

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.

S. Quezada, I. Melero, M. Rodriguez-Ruiz, 2018, Cancer research.

CD4 /CD25 Regulatory Cells Inhibit Activation of Tumor-Primed CD4 T Cells with IFN- -Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination

I. Melero, J. Lasarte, N. Casares, 2003 .

In Vitro and In Vivo Down-Regulation of Regulatory T Cell Activity with a Peptide Inhibitor of TGF- 1

J. Lasarte, J. Riezu-Boj, P. Sarobe, 2008 .

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine‐induced liver damage

P. Boya, J. Prieto, J. Lasarte, 2003 .

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage.

P. Boya, J. Prieto, J. Lasarte, 2003, Hepatology.

Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells

C. Mathieu, C. Gysemans, J. Lasarte, 2016, Diabetes.

StimulationEnhances T Cell Function after TCR Inhibition of FOXP3/NFAT Interaction

J. Oyarzábal, P. Coffer, S. Hervás-Stubbs, 2015 .

Relevance of CD6-Mediated Interactions in the Regulation of Peripheral T-Cell Responses and Tolerance

J. Lasarte, P. Engel, N. Casares, 2017, Front. Immunol..

Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.

G. Kroemer, E. Solary, M. Moutet, 2004, Cancer research.

Therapeutic blockade of Foxp3 in experimental breast cancer models

E. D. Bal de Kier Joffé, J. Lasarte, M. Candolfi, 2017, Breast Cancer Research and Treatment.

The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo1

J. Prieto, C. Leclerc, S. Hervás-Stubbs, 2007, The Journal of Immunology.

Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection

J. Heeney, J. Prieto, T. Wakita, 2007, Journal of Virology.

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein.

J. Prieto, J. Lasarte, J. Riezu-Boj, 2009, Journal of hepatology.

Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma

F. Prósper, X. Agirre, V. Basso, 2022, Frontiers in Immunology.

Cellular cytotoxicity is a form of immunogenic cell death

I. Melero, M. Rodriguez-Ruiz, P. Berraondo, 2020, Journal for ImmunoTherapy of Cancer.

Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants

I. Melero, G. González-Aseguinolaza, S. Hervás-Stubbs, 2021, Journal for ImmunoTherapy of Cancer.

Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide.

J. Prieto, C. Qian, F. Corrales, 1999, Journal of immunology.

Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus.

J. Prieto, Á. Vales, J. Lasarte, 2002, Vaccine.

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

J. San Miguel, F. Prósper, Flor Navarro, 2022, Journal for ImmunoTherapy of Cancer.

A new immune-nanoplatform for promoting adaptive antitumor immune response.

P. Berraondo, I. Trocóniz, S. Zalba, 2019, Nanomedicine : nanotechnology, biology, and medicine.

Today's Special on the Anticancer Menu: Immunomodulation by Antifolates

L. Galluzzi, A. Buqué, N. Casares, 2019, Clinical Cancer Research.

FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma

S. Hervás-Stubbs, J. Lasarte, N. Casares, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Olfactory Characterization and Training in Older Adults: Protocol Study

J. Lasarte, J. Fernández-Irigoyen, E. Santamaría, 2021, Frontiers in Aging Neuroscience.

Calreticulin exposure dictates the immunogenicity of cancer cell death

L. Zitvogel, G. Kroemer, J. Perfettini, 2007, Nature Medicine.

Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins

J. Prieto, J. Lasarte, P. Sarobe, 2002, Journal of Virology.

Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

F. Prósper, G. González-Aseguinolaza, J. Lasarte, 2021, Emerging microbes & infections.

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.

J. Martinez-Climent, Karen L. Bunting, A. Melnick, 2019, Blood.

Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-α

P. Berraondo, J. Lasarte, N. Casares, 2019, The Journal of Immunology.

Apoptosis regulation in tetraploid cancer cells

L. Zitvogel, G. Kroemer, W. Vainchenker, 2006, The EMBO journal.

The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo1

J. Prieto, C. Leclerc, S. Hervás-Stubbs, 2007, The Journal of Immunology.

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

L. Zitvogel, G. Kroemer, N. Chaput, 2005, The Journal of experimental medicine.

Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

F. Prósper, G. De Velasco, X. Agirre, 2019, Nature Medicine.

Peptide inhibitors of transforming growth factor‐β enhance the efficacy of antitumor immunotherapy

J. Prieto, P. Berraondo, J. Lasarte, 2009, International journal of cancer.

Immune response against dying tumor cells.

L. Zitvogel, G. Kroemer, N. Chaput, 2004, Advances in immunology.

A novel dendritic cell subset involved in tumor immunosurveillance

P. Opolon, L. Zitvogel, G. Kroemer, 2006, Nature Medicine.

AIF deficiency compromises oxidative phosphorylation

P. Bénit, G. Kroemer, N. Debili, 2004, The EMBO journal.

The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer

José L Carrascosa, Teresa Lozano, Pablo Sarobe, 2017, Oncoimmunology.

Cellular immunity to hepatitis C virus core protein and the response to interferon in patients with chronic hepatitis C

J. Prieto, J. Lasarte, M. Civeira, 1998, Hepatology.

A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice

J. Prieto, J. Lasarte, J. Riezu-Boj, 2010, The Journal of Immunology.

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides.

J. Prieto, J. Lasarte, P. Sarobe, 1999, International immunology.

Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms

J. Martinez-Climent, J. Prieto, O. Rabal, 2017, Haematologica.

Searching for the Achilles Heel of FOXP3

J. Lasarte, N. Casares, T. Lozano, 2013, Front. Oncol..

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

J. Martinez-Climent, F. Prósper, J. Martín-Subero, 2017, Nature Communications.

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

P. Pereira, L. Zitvogel, G. Kroemer, 2011, The Journal of experimental medicine.

Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model

P. Berraondo, I. Trocóniz, G. Kochan, 2021, Journal of Nanobiotechnology.

CD4+/CD25+ Regulatory Cells Inhibit Activation of Tumor-Primed CD4+ T Cells with IFN-γ-Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination 1

J. Prieto, I. Melero, J. Lasarte, 2003, The Journal of Immunology.

Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor

J. Prieto, O. Rabal, J. Oyarzábal, 2017, Oncotarget.

Immunization with a tumor‐associated CTL epitope plus a tumor‐related or unrelated Th1 helper peptide elicits protective CTL immunity

J. Prieto, I. Melero, J. Lasarte, 2001, European journal of immunology.

Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies

J. Lasarte, M. Esteban, J. García-Arriaza, 2023, Frontiers in Immunology.

A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

J. Prieto, J. Lasarte, P. Sarobe, 2013, BioMed research international.

Engineering Th determinants for efficient priming of humoral and cytotoxic T cell responses.

J. Prieto, J. Lasarte, P. Sarobe, 2003, International immunology.

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens

P. Romero, J. Carrascosa, S. Hervás-Stubbs, 2020, Journal for immunotherapy of cancer.

Induction of Multiepitopic and Long‐Lasting Immune Responses Against Tumour Antigens by Immunization with Peptides, DNA and Recombinant Adenoviruses Expressing Minigenes

J. Prieto, E. Huarte, J. Lasarte, 2009, Scandinavian journal of immunology.

Targeting inhibition of Foxp3 by a CD28 2'-Fluro oligonucleotide aptamer conjugated to P60-peptide enhances active cancer immunotherapy.

J. Lasarte, N. Casares, M. M. Soldevilla, 2016, Biomaterials.

Contribution of IL-17-producing gammadelta T cells to the efficacy of anticancer chemotherapy.

P. Pereira, L. Zitvogel, G. Kroemer, 2020 .

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

P. Pereira, L. Zitvogel, G. Kroemer, 2011, The Journal of Experimental Medicine.

In vivo depletion of T lymphocyte-specific transcription factors by RNA interference

L. Zitvogel, O. Kepp, G. Kroemer, 2010, Cell cycle.

Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies

S. Hervás-Stubbs, J. Lasarte, A. Lujambio, 2019, Frontiers in Immunology.

A core of kinase-regulated interactomes defines the neoplastic MDSC lineage

S. Knapp, A. Chaikuad, J. Fernández-Irigoyen, 2015, Oncotarget.

Silver nanoparticles induce a non-immunogenic tumor cell death.

P. Berraondo, N. Casares, N. Bogdanchikova, 2023, Journal of immunotoxicology.

Intratumoral STING Agonist Injection Combined with Irreversible Electroporation Delays Tumor Growth in a Model of Hepatocarcinoma

Flor Navarro, J. Lasarte, N. Casares, 2021, BioMed research international.

Impact of tumor microenvironment on adoptive T cell transfer activity.

Flor Navarro, S. Hervás-Stubbs, J. Lasarte, 2022, International review of cell and molecular biology.

Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells

Flor Navarro, J. Lasarte, J. Fernández-Irigoyen, 2023, Frontiers in Immunology.

Antigen: the Role of Nitric Oxide Immune Response to a Coadministered Expressing IL-12 Enhance or Depress the Different Doses of Adenoviral Vector

C. Qian, F. Corrales, Xiaoming Xie, 1999 .

Therapeutic Effect of Irreversible Electroporation in Combination with Poly-ICLC Adjuvant in Preclinical Models of Hepatocellular Carcinoma.

S. Hervás-Stubbs, J. Lasarte, J. Bilbao, 2019, Journal of vascular and interventional radiology : JVIR.

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.

B. Sangro, J. Lasarte, E. Larrea, 2011, Journal of hepatology.

Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma.

H. Matthaei, J. Lasarte, P. Sarobe, 2023, Immunological investigations.

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.

S. Quezada, I. Melero, M. Rodriguez-Ruiz, 2018, Cancer research.

FOXP3 Inhibitory Peptide P60 Increases Efficacy of Cytokine-induced Killer Cells Against Renal and Pancreatic Cancer Cells

C. Strassburg, J. Lasarte, M. Gonzalez-Carmona, 2019, AntiCancer Research.

Intratumoral co‐injection of NK cells and NKG2A‐neutralizing monoclonal antibodies

P. Berraondo, S. Hervás-Stubbs, Á. Teijeira, 2023, EMBO molecular medicine.

Targeting FOXP3 Tumor-Intrinsic Effects Using Adenoviral Vectors in Experimental Breast Cancer

J. Lasarte, M. Candolfi, N. Casares, 2023, Viruses.