D. Tomita

发表

Design and synthesis of potent inhibitor of apoptosis (IAP) proteins antagonists bearing an octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline mimetic.

T. Kojima, M. Yabuki, Sei Yoshida, 2013, Journal of medicinal chemistry.

Design and synthesis of a monocyclic derivative as a selective ACC1 inhibitor by chemical modification of biphenyl ACC1/2 dual inhibitors.

D. Tomita, Hiroyuki Sumi, R. Mizojiri, 2021, Bioorganic & medicinal chemistry.

Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.

L. Cantley, A. Stamford, S. Kargman, 2019, Bioorganic & medicinal chemistry letters.

Excited State Relaxation Processes of Naphthalocyanatovanadium(IV) oxide in Polymer Films for Ultrafast All-optical Modulation in the Near-infrared Region

T. Nagamura, Fuyuki Ito, D. Tomita, 2008 .

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

R. Hara, M. Yabuki, Naoki Tomita, 2016, Molecular Cancer Therapeutics.

Nucleophilic activation of alkenyl and aryl boronates by a chiral Cu(I)F complex: catalytic enantioselective alkenylation and arylation of aldehydes.

M. Kanai, M. Shibasaki, D. Tomita, 2006, Chemistry, an Asian journal.

Excited-state relaxation process of free-base and oxovanadium naphthalocyanine in near-infrared region.

T. Nagamura, Tatsuaki Inoue, Fuyuki Ito, 2009, The journal of physical chemistry. B.

Catalytic enantioselective alkenylation and phenylation of trifluoromethyl ketones

M. Kanai, M. Shibasaki, D. Tomita, 2006 .

Enantioselective alkenylation and phenylation catalyzed by a chiral CuF complex.

M. Kanai, M. Shibasaki, D. Tomita, 2005, Journal of the American Chemical Society.

Chemoselectivity of the Ru-catalyzed cycloisomerization reaction for the synthesis of dihydropyrans; application to the synthesis of L-forosamine.

D. Tomita, Feng Xu, Michael J. Zacuto, 2010, Organic letters.

Enantioselective synthesis of SM-130686 based on the development of asymmetric Cu(I)F catalysis to access 2-oxindoles containing a tetrasubstituted carbon.

M. Kanai, K. Yamatsugu, M. Shibasaki, 2009, Journal of the American Chemical Society.

Practical synthesis of chiral ligands for catalytic enantioselective cyanosilylation of ketones and ketoimines.

M. Kanai, M. Shibasaki, Nobuki Kato, 2004, The Journal of organic chemistry.

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

K. Saikatendu, C. Arrowsmith, M. Schapira, 2018, Oncotarget.

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation

T. Tuschl, D. Patel, W. Xie, 2019, Proceedings of the National Academy of Sciences.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

A chemical strategy toward novel brain-penetrant EZH2 inhibitors

M. Foley, A. Stamford, N. Liverton, 2021, bioRxiv.

Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response

R. Nishigaki, A. Ando, A. Nakamura, 2018, Proceedings of the National Academy of Sciences.

Discovery of Novel Selective Acetyl-CoA Carboxylase (ACC) 1 Inhibitors.

H. Banno, D. Tomita, Moriteru Asano, 2018, Journal of medicinal chemistry.