S. Ren

发表

Anti-Proteinase 3 Anti-Neutrophil Cytoplasm Autoantibodies Recapitulate Systemic Vasculitis in Mice with a Humanized Immune System

C. Alpers, J. Duffield, C. Savage, 2012, PloS one.

Wnt signalling in kidney diseases: dual roles in renal injury and repair

J. Duffield, S. Ren, Takahisa Kawakami, 2013, The Journal of pathology.

Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism.

J. Pfeilschifter, A. Huwiler, S. Ren, 2006, Biochimica et biophysica acta.

A Novel Mode of Action of the Putative Sphingosine Kinase Inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) Thiazole (SKI II): Induction of Lysosomal Sphingosine Kinase 1 Degradation

J. Pfeilschifter, A. Huwiler, C. Xin, 2010, Cellular Physiology and Biochemistry.

Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS.

V. D’Agati, C. Alpers, J. Duffield, 2015, Journal of the American Society of Nephrology : JASN.

Metchnikoff's policemen: macrophages in development, homeostasis and regeneration.

J. Duffield, R. Lang, S. Ren, 2011, Trends in molecular medicine.

PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism.

J. Pfeilschifter, H. Pavenstädt, A. Huwiler, 2005, Biochemical and biophysical research communications.

Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide

J. Pfeilschifter, A. Huwiler, C. Xin, 2003, British journal of pharmacology.

Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner

J. Pfeilschifter, S. Schwalm, A. Huwiler, 2008, Biological chemistry.

Sphingosine 1-Phosphate Cross-activates the Smad Signaling Cascade and Mimics Transforming Growth Factor-β-induced Cell Responses*

J. Pfeilschifter, A. Huwiler, C. Xin, 2004, Journal of Biological Chemistry.

Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase.

J. Pfeilschifter, A. Huwiler, C. Xin, 2002, European journal of pharmacology.

Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes.

J. Pfeilschifter, H. Pavenstädt, A. Huwiler, 2003, Biochemical and biophysical research communications.

Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y2 purinoceptor in renal mesangial cells

J. Pfeilschifter, A. Huwiler, S. Dorsch, 2002, British journal of pharmacology.

The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells

J. Pfeilschifter, A. Huwiler, C. Xin, 2006, British journal of pharmacology.

LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1

R. Moon, J. Duffield, R. Lang, 2013, Proceedings of the National Academy of Sciences.

Cysteamine modulates oxidative stress and blocks myofibroblast activity in CKD.

J. Duffield, J. Gangoiti, B. Barshop, 2014, Journal of the American Society of Nephrology : JASN.

Pericytes in kidney fibrosis

J. Duffield, S. Ren, 2013, Current opinion in nephrology and hypertension.

Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats.

D. Mihálik, J. Pfeilschifter, A. Huwiler, 2004, Biochemical and biophysical research communications.

Heterologous desensitization of the sphingosine‐1‐phosphate receptors by purinoceptor activation in renal mesangial cells

J. Pfeilschifter, A. Huwiler, C. Xin, 2004, British journal of pharmacology.

Biotransformation of d-Limonene to (+)trans-Carveol by Toluene-Grown Rhodococcus opacusPWD4 Cells

B. Witholt, W. Duetz, S. Ren, 2001, Applied and Environmental Microbiology.

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

Aaron N. Chang, S. Orkin, Jochen C. Hartner, 2012, Science Translational Medicine.

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Naoki Nakagawa, Jonathan Himmelfarb, D. Mackenna, 2015, The Journal of clinical investigation.

Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis

J. Duffield, S. Shankland, C. Xin, 2015, Kidney international.

Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor-Related Protein 6.

G. Karaca, J. Duffield, George Locke, 2017, Journal of the American Society of Nephrology : JASN.

Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.

J. Pfeilschifter, H. Pavenstädt, A. Huwiler, 2009, Kidney international.

Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.

Lin Sun, Z. Dong, Yu Liu, 2019, Kidney international.

Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1β-induced prostaglandin E2 formation Published, JLR Papers in Press, June 25, 2007.

J. Pfeilschifter, A. Huwiler, C. Xin, 2007, Journal of Lipid Research.

FTY720 suppresses interleukin‐1β‐induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism

J. Pfeilschifter, A. Huwiler, C. Xin, 2007, British journal of pharmacology.

Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury.

J. Duffield, G. Ligresti, A. Aplin, 2017, Biomaterials.

A Novel Three-Dimensional Human Peritubular Microvascular System.

Ying Zheng, Jun Xue, Susan K. Anderson, 2016, Journal of the American Society of Nephrology : JASN.

Association between GLP-1R gene polymorphism and dyslipidemia in Chinese patients with type 2 diabetes mellitus: a case-control study.

S. Ren, Yundi Zhang, Yue Li, 2023, Gene.

Wnt signalling in kidney diseases: dual roles in renal injury and repair

J. Duffield, S. Ren, Takahisa Kawakami, 2013, The Journal of pathology.

A Novel Three-Dimensional Human Peritubular Microvascular System.

James W. MacDonald, S. Schwartz, J. Himmelfarb, 2016, Journal of the American Society of Nephrology : JASN.