B. Magliaro

发表

Discovery, Optimization, and Biological Characterization of 2,3,6‐Trisubstituted Pyridine‐Containing M4 Positive Allosteric Modulators

Scott T. Harrison, J. Uslaner, Sean M. Smith, 2019, ChemMedChem.

Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators

K. Rhodes, E. Lo, Xiaoying Wang, 2007, Neuroscience Letters.

Mechanism based neurotoxicity of mGlu5 positive allosteric modulators – Development challenges for a promising novel antipsychotic target

Sarah L. Huszar, J. Uslaner, T. Tucker, 2014, Neuropharmacology.

Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis.

Sarah L. Huszar, J. Uslaner, M. Jacobson, 2016, Bioorganic & medicinal chemistry letters.

Clozapine protects PC-12 cells from death due to oxidative stress induced by hydrogen peroxide via a cell-type specific mechanism involving inhibition of extracellular signal-regulated kinase phosphorylation

C. Saldanha, B. Magliaro, 2009, Brain Research.

Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

K. Rhodes, B. Shook, Xun Li, 2010, Bioorganic & medicinal chemistry letters.

Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI.

Leo A. Joyce, Sarah L. Huszar, J. Uslaner, 2016, ACS medicinal chemistry letters.

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts.

Sarah L. Huszar, J. Uslaner, C. Culberson, 2010, Bioorganic & medicinal chemistry letters.

Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor.

Sarah L. Huszar, J. Uslaner, M. Jacobson, 2010, ACS medicinal chemistry letters.

The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents

Lynn A. Hyde, J. Uslaner, Sean M. Smith, 2011, Neuropharmacology.

Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4 Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases.

Scott T. Harrison, M. Rudd, F. Monsma, 2020, Journal of medicinal chemistry.