A. Maynard

发表

Quantifying, Visualizing, and Monitoring Lead Optimization.

Andrew T Maynard, A. Maynard, C. D. Roberts, 2016, Journal of medicinal chemistry.

TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION.

C. Cameron, W. Kazmierski, D. Cordek, 2011, Drugs of the future.

Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.

D. Covell, E. Appella, A. Wallqvist, 1999, Journal of medicinal chemistry.

Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.

D. Covell, William Q. Rice, W. Rice, 1998, Journal of medicinal chemistry.

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

R. Hamatake, Z. Hong, Shawn P. Williams, 2014, Journal of medicinal chemistry.

Reactivity of the HIV-1 nucleocapsid protein p7 zinc finger domains from the perspective of density-functional theory.

D. Covell, W. Rice, A. Maynard, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Reactivity of zinc finger cores: analysis of protein packing and electrostatic screening.

D. Covell, A. Maynard, 2001, Journal of the American Chemical Society.

Charge reversal of the conjugate base of formamide

M. M. Bursey, A. Maynard, J. Kiplinger, 1987 .

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

D. J. Price, John Miller, Shawn P. Williams, 2019, Journal of medicinal chemistry.

HCV Inhibition Mediated Through the Nonstructural Protein 5A (NS5A) Replication Complex

R. Hamatake, W. Kazmierski, A. Maynard, 2012 .

A theoretical study of the minimum energy structures of diethylstilbestrol and its analogues by molecular mechanics (MM2p), MNDO, and ab initio calculations

T. Darden, L. Pedersen, K. Gottschalk, 1986 .

Effect of calcium (II) and magnesium (II) ions on the 18-23 gamma-carboxyglutamic acid containing cyclic peptide loop of bovine prothrombin. An AMBER molecular mechanics study.

T. Darden, L. Pedersen, D. Deerfield, 2009, International journal of peptide and protein research.

An ab initio mo study of calcium and magnesium complexes with malonate and formate

L. Pedersen, R. Hiskey, K. Koehler, 1985 .

Naturally Occurring CCR5 Extracellular and Transmembrane Domain Variants Affect HIV-1 Co-receptor and Ligand Binding Function*

A. Maynard, J. Oppenheim, J. Turpin, 1999, The Journal of Biological Chemistry.

Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome

D. J. Price, N. Katsanis, P. L. Tan, 2018, Scientific Reports.

Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor

E. Appella, W. Farrar, Xiaohu Zhang, 2004, Nature Medicine.

A Theoretical Study of the Minimum Energy Structures of Diethylstilbestrol (I) and Its Analogues (II), (III) by Molecular Mechanics (MM2p), MNDO, and ab initio Calculations.

T. Darden, L. Pedersen, K. Gottschalk, 1986 .

An Ab initio study of the relationship between nitroarene mutagenicity and electron affinity.

L. Pedersen, J. McKinney, A. Maynard, 1986, Molecular pharmacology.

Matrix Isolation Infrared and ab Initio Study of the 1:1 Complexes of Cyclopentadiene with Nitrogen and Oxygen Bases: C-H---N(O) Hydrogen Bonding Involving an sp3-Hybridized Carbon

A. Maynard, E. Mysak, Cindy Samet, 2001 .

A quantum dynamical study of CH overtones in fluoroform. I. A nine‐dimensional ab initio surface, vibrational spectra and dynamics

Christophe Iung, Robert E. Wyatt, Andrew Maynard, 1995 .

Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein.

D. J. Price, J. Pouliot, A. Maynard, 2014, Bioorganic & medicinal chemistry letters.

Matrix Isolation Infrared and ab Initio Study of the 1:1 Complexes of Bromocyclopropane with NH3 and (CH3)3N: Evidence for a Novel C−H···N Hydrogen Bond

A. Maynard, Leah Goldfarb, A. E. Mysak, 1999 .

Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome

N. Katsanis, P. L. Tan, C. Golzio, 2018, Scientific Reports.

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

S. Stahl, S. Durell, E. Appella, 2006, Journal of the American Chemical Society.

Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: from lead to clinical compound.

R. Hamatake, W. Kazmierski, R. Crosby, 2014, Journal of medicinal chemistry.

Statistical tools for virtual screening.

Jennifer R. Krumrine, Jennifer R Krumrine, Andrew T Maynard, 2005, Journal of medicinal chemistry.