P. Komalavilas

发表

Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide

T. Lincoln, R. Weisbrod, R. Cohen, 1998, British journal of pharmacology.

Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts.

C. Flynn, M. Longaker, C. Brophy, 2009, The Journal of investigative dermatology.

Vasorelaxing cell permeant phosphopeptide mimetics for subarachnoid hemorrhage.

J. Mocco, R. Thompson, C. Brophy, 2021, European journal of pharmacology.

umbilical artery smooth muscle protein 20, HSP20, prevents vasospasm of human Transduction of phosphorylated heat shock-related

C. Flynn, C. Brophy, N. Gusev, 2013 .

Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli.

C. Flynn, L. Mandarino, C. Brophy, 2007, Protein expression and purification.

A cell permeant phosphopeptide mimetic of Niban inhibits p38 MAPK and restores endothelial function after injury

Joyce Cheung-Flynn, P. Komalavilas, M. Polcz, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The small heat shock protein, HSPB6, in muscle function and disease

C. Flynn, C. Brophy, P. Komalavilas, 2009, Cell Stress and Chaperones.

The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.

C. Flynn, C. Brophy, Manhong Guo, 2008, American journal of physiology. Lung cellular and molecular physiology.

Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia.

C. Brophy, K. Hocking, K. Sexton, 2016, Journal of vascular surgery.

Detrimental effects of mechanical stretch on smooth muscle function in saphenous veins.

C. Brophy, K. Hocking, Joyce Cheung-Flynn, 2011, Journal of vascular surgery.

Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein.

C. Brophy, K. Hocking, Igor V. Voskresensky, 2014, Journal of vascular surgery.

Localization, Macromolecular Associations, and Function of the Small Heat Shock–Related Protein HSP20 in Rat Heart

C. Brophy, T. Creazzo, P. Komalavilas, 2003, Circulation.

Role of the renin-angiotensin system in the pathogenesis of intimal hyperplasia: therapeutic potential for prevention of vein graft failure?

D. Harrison, C. Brophy, K. Hocking, 2012, Annals of vascular surgery.

Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury.

C. Brophy, K. Hocking, Joyce Cheung-Flynn, 2016, Journal of vascular surgery.

Anhydrous Hydrogen Fluoride and Cell-Wall Analysis

G. Rorrer, A. Mort, P. Komalavilas, 1989 .

Phosphorylation of the Inositol 1,4,5-Trisphosphate Receptor

T. Lincoln, P. Komalavilas, 1996, The Journal of Biological Chemistry.

Papaverine Prevents Vasospasm by Regulation of Myosin Light Chain Phosphorylation and Actin Polymerization in Human Saphenous Vein

C. Brophy, K. Hocking, E. Wise, 2016, PloS one.

Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo.

Kinam Park, C. Brophy, Namho Kim, 2012, Vascular pharmacology.

A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model.

C. Flynn, B. Bowen, C. Brophy, 2010, Journal of vascular surgery.

Phosphorylation and activation of a transducible recombinant form of human HSP20 in E. coli

C. Flynn, L. Mandarino, C. Brophy, 2008 .

Surgical Skin Markers Impair Human Saphenous Vein Graft Smooth Muscle and Endothelial Function

C. Brophy, K. Hocking, K. Sexton, 2011, The American surgeon.

Role of the small heat shock proteins in regulating vascular smooth muscle tone.

C. Brophy, E. Mclemore, P. Komalavilas, 2005, Journal of the American College of Surgeons.

Transduction of phosphorylated heat shock-related protein 20, HSP20, prevents vasospasm of human umbilical artery smooth muscle.

C. Flynn, C. Brophy, L. Joshi, 2005, Journal of applied physiology.

Transducible recombinant small heat shock-related protein, HSP20, inhibits vasospasm and platelet aggregation.

C. Flynn, C. Brophy, L. Joshi, 2004, Surgery.

Phosphorylation of the heat shock-related protein, HSP20, mediates cyclic nucleotide-dependent relaxation.

C. Brophy, P. Komalavilas, D. Tessier, 2003, Journal of vascular surgery.

Cell-permeant peptide inhibitors of vasospasm and intimal hyperplasia

C. Flynn, C. Brophy, P. Komalavilas, 2013, Vascular.

Pressure control during preparation of saphenous veins.

C. Brophy, K. Hocking, Joyce Cheung-Flynn, 2014, JAMA surgery.

Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways

Kalyana Chadalavada, C. Brophy, K. Hocking, 2019, PloS one.

Preservation solution impacts physiologic function and cellular viability of human saphenous vein graft.

C. Brophy, K. Hocking, E. Wise, 2015, Surgery.

An Optimized Preparation Technique for Saphenous Vein Graft

C. Brophy, K. Hocking, E. Wise, 2015, The American surgeon.

Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis

J. Bastarache, L. Ware, C. Brophy, 2022, Physiological reports.

Sildenafil-induced vasorelaxation is associated with increases in the phosphorylation of the heat shock-related protein 20 (HSP20).

C. Brophy, P. Komalavilas, D. Tessier, 2004, The Journal of surgical research.

Calcification of Human Saphenous Vein Associated with Endothelial Dysfunction: A Pilot Histopathophysiological and Demographical Study

C. Brophy, K. Hocking, Joyce Cheung-Flynn, 2017, Front. Surg..

R. Peebles, D. Newcomb, Joyce Cheung-Flynn, 2016, American journal of respiratory cell and molecular biology.

Arabinogalactan-proteins from the suspension culture medium and plasma membrane of rose cells.

E. Nothnagel, P. Komalavilas, J. K. Zhu, 1991, The Journal of biological chemistry.

PI3-kinase/Akt modulates vascular smooth muscle tone via cAMP signaling pathways.

D. Dransfield, C. Brophy, C. Wingard, 2001, Journal of applied physiology.

Enhanced skin penetration of P20 phosphopeptide using protein transduction domains.

C. Brophy, A. Panitch, P. Komalavilas, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

C. Brophy, Joyce Cheung-Flynn, P. Komalavilas, 2017, PloS one.

Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation

D. Flaherty, J. Rathmell, K. Boyd, 2022, Communications biology.

Cyclic GMP-Mediated Signaling Mechanisms in Smooth Muscle

T. Lincoln, P. Komalavilas, 2000 .

The acetylation of O-3 of galacturonic acid in the rhamnose-rich portion of pectins

Andrew J. Mort, A. Mort, P. Komalavilas, 1989 .

Traditional graft preparation decreases physiologic responses, diminishes viscoelasticity, and reduces cellular viability of the conduit: A porcine saphenous vein model

C. Brophy, K. Hocking, E. Wise, 2016, Vascular medicine.

Intimal thickness associated with endothelial dysfunction in human vein grafts.

C. Brophy, K. Hocking, K. Sexton, 2013, The Journal of surgical research.

Brilliant blue FCF as an alternative dye for saphenous vein graft marking: effect on conduit function.

C. Brophy, K. Hocking, Igor V. Voskresensky, 2014, JAMA surgery.

Pleiotropic regulation of vascular smooth muscle tone by cyclic GMP-dependent protein kinase.

T. Lincoln, T. Cornwell, P. Komalavilas, 1994, Hypertension.

Regulation of Intracellular Ca2+ by Cyclic GMP-Dependent Protein Kinase in Vascular Smooth Muscle Cells

T. Lincoln, P. Komalavilas, 2000 .

cGMP signaling through cAMP- and cGMP-dependent protein kinases.

T. Lincoln, T. Cornwell, L. MacMillan-Crow, 1995, Advances in pharmacology.

Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase.

T. Lincoln, P. Komalavilas, 1994, The Journal of biological chemistry.

Shear Stress Regulates Endothelin Receptors as Well as Endothelin-1 in Cultured Human Vascular Endothelial and Smooth Muscle Cells

P. Oettgen, W. Aird, K. Willecke, 2002 .

Nanotechnology Enabled Modulation of Signaling Pathways Affects Physiologic Responses in Intact Vascular Tissue.

Craig L Duvall, Brian C Evans, C. Duvall, 2019, Tissue engineering. Part A.

Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis

J. Bastarache, L. Ware, C. Brophy, 2020, PloS one.

Women in academic surgery: the pipeline is busted.

K. Campbell, C. Brophy, K. Hocking, 2012, Journal of surgical education.

Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics

Yuejun Zhen, J. Peltier, L. Joshi, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The small heat shock protein (HSP) 20 is dynamically associated with the actin cross-linking protein actinin.

C. Brophy, L. Joshi, A. Panitch, 2003, The Journal of surgical research.

The yin and yang of vascular smooth muscle tone

C. Brophy, P. Komalavilas, D. Tessier, 2004 .

Cyclic GMP-dependent protein kinase in nitric oxide signaling.

T. Lincoln, T. Cornwell, P. Komalavilas, 1996, Methods in enzymology.

Activation of Mitogen-activated Protein Kinase Pathways by Cyclic GMP and Cyclic GMP-dependent Protein Kinase in Contractile Vascular Smooth Muscle Cells*

T. Lincoln, P. Komalavilas, H. Jo, 1999, The Journal of Biological Chemistry.

Chapter 20 – The Nitric Oxide–Cyclic GMP Signaling System

T. Lincoln, T. Cornwell, L. MacMillan-Crow, 1996 .

Preservation solution impacts physiologic function and cellular viability of human saphenous vein graft.

C. Brophy, K. Hocking, E. Wise, 2015, Surgery.

ATP as a molecular mediator of the vascular response to injury

W. Luo, Joyce Cheung-Flynn, P. Komalavilas, 2018 .

Adenosine triphosphate as a molecular mediator of the vascular response to injury.

Kalyana Chadalavada, C. Brophy, Joyce Cheung-Flynn, 2017, The Journal of surgical research.

Cyclic nucleotides in smooth muscle

T. Lincoln, P. Komalavilas, N. Boerth, 2000 .

Comparative Study of the Skin Penetration of Protein Transduction Domains and a Conjugated Peptide

Lokesh Joshi, Olivia Sparks, Alyssa Panitch, 2005, Pharmaceutical Research.

Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor.

C. Flynn, C. Brophy, A. Panitch, 2009, Biochemical and biophysical research communications.

cGMP-Dependent Protein Kinase Expression Restores Contractile Function in Cultured Vascular Smooth Muscle Cells

J. Pollock, T. Lincoln, T. Cornwell, 2002, Journal of Vascular Research.

Protein kinase G is not essential to NO-cGMP modulation of basal tone in rat pulmonary circulation.

T. Lincoln, D. Rodman, P. Komalavilas, 1998, The American journal of physiology.

Protein kinase G is not essential to NO-cGMP modulation of basal tone in rat pulmonary circulation.

T. Lincoln, D. Rodman, P. Komalavilas, 1998, American journal of physiology. Heart and circulatory physiology.

Analysis of expression of cGMP-dependent protein kinase in rabbit heart cells.

T. Lincoln, R. W. Joyner, P. Komalavilas, 1999, The Journal of pharmacology and experimental therapeutics.

Transduction of biologically active motifs of the small heat shock‐related protein, HSP20, leads to relaxation of vascular smooth muscle

C. Flynn, R. Nelson, L. Joshi, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of Cyclic Nucleotide-Dependent Actin Cytoskeletal Dynamics: [Ca2+]i and Force Suppression in Forskolin-Pretreated Porcine Coronary Arteries

F. Baudenbacher, C. Brophy, K. Hocking, 2013, PloS one.

Transduction of peptide analogs of the small heat shock-related protein HSP20 inhibits intimal hyperplasia.

C. Brophy, Bo Liu, L. Joshi, 2004, Journal of vascular surgery.

C. Brophy, P. Komalavilas, 2004, Circulation Research.