J. Ward

发表

Philip I. Aaronson, C. Wiener, P. Aaronson, 1999 .

Determination of intracellular potassium ion concentration in isolated rat ventricular myocytes.

C. Fry, J. Ward, T. Powell, 1986, Biochemical and biophysical research communications.

Control of pH of airway surface liquid of the ferret trachea in vitro.

J. Ward, J. Widdicombe, H. Kyle, 1990, Journal of applied physiology.

during one-lung ventilation in mice vasoconstriction and enhances systemic oxygenation NOS3 deficiency augments hypoxic pulmonary

O. V. Evgenov, N. Weissmann, W. Zapol, 2015 .

A comparison of the pharmacological and mechanical properties in vitro of large and small pulmonary arteries of the rat.

I. Cameron, R. Leach, J. Ward, 1992, Clinical science.

Protein kinases in vascular smooth muscle tone--role in the pulmonary vasculature and hypoxic pulmonary vasoconstriction.

P. Aaronson, J. Ward, G. Knock, 2004, Pharmacology & therapeutics.

Excitation–Contraction Coupling and Regulation of Pulmonary Vascular Contractility

J. Ward, G. Knock, J. Ward, 2011 .

Back Matter

Bates, R. H. Ritchie, M. E. Coupland, 1999 .

Dietary soy isoflavone‐induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo

Imran Y. Khan, P. Taylor, L. Poston, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Profiling of healthy and asthmatic airway smooth muscle cells following interleukin-1β treatment: a novel role for CCL20 in chronic mucus hypersecretion

N. T. ten Hacken, A. Halayko, I. Heijink, 2018, European Respiratory Journal.

Comprar The Cardiovascular System at a Glance | Jeremy Ward | 9781405150446 | Blackwell Publishing

P. Aaronson, J. Ward, 2007 .

Regulation of GPCR-mediated smooth muscle contraction: implications for asthma and pulmonary hypertension.

J. Ward, D. Schaafsma, O. Ojo, 2013, Pulmonary pharmacology & therapeutics.

Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat

P. Aaronson, J. Ward, G. Knock, 2003, British journal of pharmacology.

Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells.

S. Smirnov, P. Aaronson, J. Ward, 1994, The American journal of physiology.

pulmonary edema epithelium in mountaineers with high-altitude Altered ion transporter expression in bronchial

D. Bailey, C. Dehnert, P. Bärtsch, 2015 .

hypoxic rats does not cause myogenic vasoconstriction pulmonary arteries from control and chronically Pressure-induced smooth muscle cell depolarization in

L. Shimoda, S. Earley, B. Walker, 2015 .

Hypoxic pulmonary vasoconstriction in the absence of pretone: essential role for intracellular Ca2+ release

P. Aaronson, J. Ward, Silke Becker, 2013, The Journal of physiology.

Ion channels in freshly isolated and cultured human bronchial smooth muscle cells

J. Ward, S. Hirst, V. Snetkov, 1996, Experimental physiology.

The mechanism of action of endothelin-1 on small pulmonary arterial vessels.

I. Cameron, R. Leach, J. Ward, 1990, Pulmonary pharmacology.

Dietary soy modulates endothelium-dependent relaxation in aged male rats: Increased agonist-induced endothelium-derived hyperpolarising factor and basal nitric oxide activity.

G. Mann, P. Aaronson, J. Ward, 2006, Free radical biology & medicine.

Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem.

J. Ward, I. McMurtry, J. Ward, 2009, Current opinion in pharmacology.

Endothelium-derived mediators and hypoxic pulmonary vasoconstriction

P. Aaronson, J. Ward, T. Robertson, 2002, Respiratory Physiology & Neurobiology.

Noradrenaline, β‐adrenoceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat

J. Ward, D. Hucks, R. M. Priest, 1997, British journal of pharmacology.

Inhibition of sustained hypoxic vasoconstriction by Y‐27632 in isolated intrapulmonary arteries and perfused lung of the rat

A. Evans, M. Dipp, P. Aaronson, 2000, British journal of pharmacology.

Repeated allergen inhalation induces phenotypic modulation of smooth muscle in bronchioles of sensitized rats.

C. G. McVicker, K. Chung, Sum-Yee Leung, 2003, American journal of physiology. Lung cellular and molecular physiology.

unaltered by nitric oxide Hypoxia-induced pulmonary endothelin-1 expression is

L. Nelin, L. Chicoine, J. Weaver, 2015 .

AFM imaging reveals the tetrameric structure of the TRPC1 channel.

R. Henderson, J. Ward, I. McFadzean, 2007, Biochemical and biophysical research communications.

following acute pulmonary thromboembolism in pigs Spatial pattern of ventilation-perfusion mismatch

H. Robertson, L. Shimoda, M. Hlastala, 2015 .

Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways

S. Smirnov, P. Aaronson, J. Ward, 2010, Cardiovascular research.

Hypoxic pulmonary hypertension; the load on the right ventricle

P. McLoughlin, J. Ward, 2013, Experimental Physiology.

On Ca2+ sensitivity and the airways: not just any smooth muscle

J. Ward, 2006, European Respiratory Journal.

vasculature depends on vascular diameter Innervation pattern of guinea pig pulmonary

W. Kummer, M. Schemann, S. Mazzone, 2015 .

Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors

A. Halayko, B. Oliver, J. Burgess, 2018, Scientific Reports.

microangiographyrat using synchrotron radiation Imaging of the pulmonary circulation in the

K. Kangawa, D. Schwenke, M. Shirai, 2012 .

Capacitative calcium entry: a central role in hypoxic pulmonary vasoconstriction?

P. Aaronson, J. Ward, T. Robertson, 2005, American journal of physiology. Lung cellular and molecular physiology.

Inhaled calcilytics: effects on airway inflammation and remodeling

E. Kidd, Y. Prakash, D. Riccardi, 2016 .

Mechanisms of leukotriene D4‐induced constriction in human small bronchioles

C. G. McVicker, T. Lee, J. Ward, 2001, British journal of pharmacology.

Point: Hypoxic pulmonary vasoconstriction is mediated by increased production of reactive oxygen species.

J. Ward, J. Ward, 2006, Journal of applied physiology.

Effects of heparin on inositol 1,4,5-trisphosphate and guanosine 5'-O-(3-thio triphosphate) induced calcium release in cultured smooth muscle cells from rabbit trachea.

I. Cameron, J. Ward, C. Twort, 1989, Biochemical and biophysical research communications.

Physiological redox signalling and regulation of ion channels: implications for pulmonary hypertension

J. Ward, J. Ward, 2017, Experimental physiology.

viscosity on hypoxic pulmonary vasoconstriction Effects of the RBC membrane and increased perfusate

M. Gladwin, S. Deem, E. Swenson, 2015 .

The role of the endothelium in hypoxic pulmonary vasoconstriction

J. Ward, T. Robertson, J. Ward, 1995, Experimental physiology.

Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.

P. Aaronson, J. Ward, Silke Becker, 2009, Free radical biology & medicine.

Transforming growth factor‐β enhances Rho‐kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1

J. Ward, G. Knock, D. Wright, 2017, The Journal of physiology.

Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery

P. Aaronson, J. Ward, S. Drndarski, 2007, Cardiovascular research.

Insulin-like growth factor-I gene expression is increased in the right ventricular hypertrophy induced by chronic hypoxia in the rat.

D. Russell-Jones, R. Leach, J. Ward, 1993, Journal of molecular endocrinology.

Physiological redox signaling in lung, cardiovascular and neural cells: Progress, controversy and potential

P. Schumacker, J. Ward, 2010, Respiratory Physiology & Neurobiology.

Modulation of PGF2alpha- and hypoxia-induced contraction of rat intrapulmonary artery by p38 MAPK inhibition: a nitric oxide-dependent mechanism.

M. Walsh, P. Aaronson, J. Ward, 2005, American journal of physiology. Lung cellular and molecular physiology.

Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.

R. Leach, P. Aaronson, J. Ward, 2005, Cardiovascular research.

Preparation of cultured airway smooth muscle for study of intracellular element concentrations by X‐ray microanalysis: Comparison of whole cells with cryosections

A. Warley, J. Ward, C. Twort, 1994, Journal of microscopy.

Mechanisms of hypoxic pulmonary vasoconstriction: can anyone be right?

P. Aaronson, J. Ward, J. Ward, 1999, Respiration physiology.

Role of capacitative Ca2+ entry but not Na+/Ca2+ exchange in hypoxic pulmonary vasoconstriction in rat intrapulmonary arteries.

P. Aaronson, J. Ward, Silke Becker, 2006, Novartis Foundation symposium.

Hypoxic pulmonary vasoconstriction: mechanisms and controversies

P. Aaronson, J. Ward, Silke Becker, 2006, The Journal of physiology.

pulmonary circulation by carbon dioxide Role of airway nitric oxide on the regulation of

H. Ghofrani, F. Grimminger, R. Schermuly, 2015 .

novel localization in vascular endothelium CYP4A mRNA, protein, and product in rat lungs:

E. Jacobs, J. Falck, R. Roman, 2015 .

endotheliumss between rat strains: role of Differences in acute hypoxic pulmonary

D. Gozal, Shelley X. L. Zhang, N. Hill, 2015 .

Alterations to potassium fluxes in the heart during chronic dietary potassium depletion.

I. Cameron, J. Ward, J. Ward, 1985, Journal of molecular and cellular cardiology.

Endothelium-dependent Hypoxic Pulmonary Vasoconstriction

P. Aaronson, J. Ward, 2004 .

Final general discussion

J. López-Barneo, M. Duchen, N. Chandel, 2006 .

Essential role of L‐arginine uptake and protein tyrosine kinase activity for NO‐dependent vasorelaxation induced by stretch, isometric tension and cyclic AMP in rat pulmonary arteries

J. Ward, D. Hucks, Nayeem M Khan, 2000, British journal of pharmacology.

pulmonary vascular tone in the newborn rat A bronchial epithelium-derived factor reduces

Jullie W Pan, A. Tanswell, P. Vanhoutte, 2015 .

Hypoxic vasoconstriction and intracellular Ca2+ in pulmonary arteries: evidence for PKC-independent Ca2+ sensitization.

P. Aaronson, J. Ward, T. Robertson, 1995, The American journal of physiology.

echocardiographyand hypocapnia measured using Doppler Human pulmonary vascular response to 4 h of

P. Robbins, G. Thomas, C. Vrints, 2015 .

Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization

P. Aaronson, J. Ward, Silke Becker, 2013, Cardiovascular research.

Low Concentrations of Sphingosylphosphorylcholine Enhance Pulmonary Artery Vasoreactivity: The Role of Protein Kinase C&dgr; and Ca2+ Entry

R. Leach, P. Aaronson, J. Ward, 2008, Hypertension.

Constriction of pulmonary artery by peroxide: role of Ca2+ release and PKC.

P. Aaronson, J. Ward, S. Drndarski, 2008, Free radical biology & medicine.

Hypoxic pulmonary vasoconstriction.

L. Shimoda, P. Aaronson, J. Ward, 2012, Physiological reviews.

regions of the rostral ventrolateral medulla Expression of heme oxygenase in the oxygen-sensing

G. Semenza, N. Prabhakar, J. Neubauer, 2015 .

Calcium Regulation in Rat Sensory Neurons Effects of Anoxia and Aglycemia on Cytosolic

J. Eilers, R. Kraft, S. Meuth, 2015 .

Direct action of BRL 38227 and glibenclamide on intracellular calcium stores in cultured airway smooth muscle of rabbit

J. Ward, C. Twort, L. C. Chopra, 1992, British journal of pharmacology.

Divergent modulation of Rho‐kinase and Ca2+ influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle

J. Ward, J. Prieto-Lloret, G. Knock, 2015, British journal of pharmacology.

pathways by Src family kinases and focal adhesion kinase in airway smooth muscle

J. Ward, J. Prieto-Lloret, G. Knock, 2015 .

Calcium, mitochondria and oxygen sensing in the pulmonary circulation.

P. Aaronson, J. Ward, V. Snetkov, 2004, Cell calcium.

Ligustrazine‐induced endothelium‐dependent relaxation in pulmonary arteries via an NO‐mediated and exogenous L‐arginine‐dependent mechanism

J. Ward, W. Peng, D. Hucks, 1996, British journal of pharmacology.

Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain following Nerve Injury

S. McMahon, Lan Zhu, G. Michael, 2012, The Journal of Neuroscience.

Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors

A. Halayko, B. Oliver, J. Burgess, 2018, Scientific Reports.

Activation of nitric oxide synthase by β2‐adrenoceptors in human umbilical vein endothelium in vitro

L. Poston, J. Ritter, A. Ferro, 1999, British journal of pharmacology.

Membrane potential-dependent and -independent vasodilation in small pulmonary arteries from chronically hypoxic rats.

R. Leach, J. Ward, T. Robertson, 1998, The Journal of pharmacology and experimental therapeutics.

venulesvasoconstriction in pulmonary arterioles and

R. Glenny, T. Gudermann, W. Seeger, 2015 .

Hypoxic vasoconstriction in rat pulmonary and mesenteric arteries.

R. Leach, J. Ward, C. Twort, 1994, The American journal of physiology.

Euhydric hypercapnia increases vasoreactivity of rat pulmonary arteries via HCO3- transport and depolarisation.

P. Aaronson, J. Ward, G. Knock, 2005, Cardiovascular research.

ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1

J. Ward, G. Knock, C. MacKay, 2017, Free radical biology & medicine.

Hypoxic pulmonary vasoconstriction--invited article.

J. Ward, A. Mark Evans, J. Ward, 2009, Advances in experimental medicine and biology.

Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery

P. Aaronson, J. Ward, S. Drndarski, 2008, Cardiovascular research.

Ca2+ sensitization during sustained hypoxic pulmonary vasoconstriction is endothelium dependent.

P. Aaronson, J. Ward, T. Robertson, 2003, American journal of physiology. Lung cellular and molecular physiology.

Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor

R. Leach, J. Ward, V. Snetkov, 2001, The Journal of physiology.

Hypoxia induces the release of a pulmonary-selective, Ca(2+)-sensitising, vasoconstrictor from the perfused rat lung.

P. Aaronson, J. Ward, T. Robertson, 2001, Cardiovascular research.

Mechanisms of the prostaglandin F2α‐induced rise in [Ca2+]i in rat intrapulmonary arteries

P. Aaronson, J. Ward, G. Knock, 2006, The Journal of physiology.

Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma

B. Kariuki, E. Kidd, D. Riccardi, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Oxygen regulates mitogen-stimulated proliferation of fetal human airway smooth muscle cells.

H. Pandya, J. Ward, C. Twort, 2002, American journal of physiology. Lung cellular and molecular physiology.

Oxygen sensors in context.

J. Ward, Jeremy P T Ward, J. Ward, 2008, Biochimica et biophysica acta.

The effects of dietary potassium depletion on the ultrastructure of cardiac ventricular myocytes in rabbits: a morphometric study.

J. Skepper, A. Warley, J. Ward, 1991, Journal of anatomy.

normoxiagas exchange in normal primate lungs during Vasomotor tone does not affect perfusion heterogeneity

Amran K. Asadi, G. Prisk, R. Buxton, 2013 .

Ca2+ handling and sensitivity in airway smooth muscle: emerging concepts for mechanistic understanding and therapeutic targeting.

J. Ward, X. Tan, C. Nelson, 2014, Pulmonary pharmacology & therapeutics.

Effects of protein tyrosine kinase inhibitors on contractility of isolated bronchioles of the rat.

J. Ward, C. Twort, D. Hucks, 1997, American journal of respiratory cell and molecular biology.

Oral spray of isobutyl cyanoacrylate and its systemic effect.

J. Ward, D. E. Cutright, S. Bhaskar, 1970, Oral surgery, oral medicine, and oral pathology.

Hypoxia, energy state and pulmonary vasomotor tone

R. Leach, J. Ward, V. Snetkov, 2002, Respiratory Physiology & Neurobiology.

Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H2S-synthesizing pathways

P. Aaronson, J. Ward, J. Prieto-Lloret, 2015, The Journal of physiology.

The Respiratory System at a Glance

C. Wiener, R. Leach, J. Ward, 2002 .

Determination of signaling pathways responsible for hypoxic pulmonary vasoconstriction: use of the small vessel myograph.

J. Ward, V. Snetkov, 2004, Methods in enzymology.

Net calcium exchange in adult rat ventricular myocytes: an assessment of mitochondrial calcium accumulating capacity

C. Fry, J. Ward, T. Powell, 1984, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Differences in sensitivity to the specific protein kinase C inhibitor Ro31‐8220 between small and large bronchioles of the rat

J. Ward, C. Twort, L. C. Chopra, 1994, British journal of pharmacology.

Bidirectional cross-regulation between the endothelial nitric oxide synthase and β-catenin signalling pathways

Qingbo Xu, A. Ferro, J. Ward, 2014, Cardiovascular research.

From Physiological Redox Signalling to Oxidant Stress.

J. Ward, J. Ward, 2017, Advances in experimental medicine and biology.

Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species

S. Smirnov, P. Aaronson, J. Ward, 2015, Cardiovascular research.

Membrane receptors, channels and transporters in pulmonary circulation

J. Yuan, J. Ward, 2010 .

Potassium Channels in Human Fetal Airway Smooth Muscle Cells

H. Pandya, J. Ward, S. Hirst, 1998, Pediatric Research.

Vasopressin and oxytocin release during prolonged environmental hypoxia in the rat.

M. Forsling, R. Leach, J. Ward, 1997, Thorax.

Variable potassium content in rabbit cultured tracheal smooth muscle cells

A. Warley, J. Ward, C. Twort, 1993, Cell Biology International.

Hypoxic pulmonary vasoconstriction.

L. Shimoda, P. Aaronson, J. Ward, 2012, Physiological reviews.

A twist in the tail: synergism between mitochondria and NADPH oxidase in the hypoxia-induced elevation of reactive oxygen species in pulmonary artery.

J. Ward, J. Ward, 2008, Free radical biology & medicine.

Voltage‐independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat

P. Aaronson, J. Ward, T. Robertson, 2000, The Journal of physiology.

The effects of sodium, hydrogen and magnesium ions on mitochondrial calcium sequestration in adult rat ventricular myocytes

C. Fry, J. Ward, T. Powell, 1984, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Hypoxic pulmonary vasoconstriction.

L. Shimoda, P. Aaronson, J. Ward, 2012, Physiological reviews.

Increased resistance to acute respiratory acidosis in isolated cardiac muscle following chronic hypoxia-induced hypertrophy.

J. Ward, N. Bateman, E. Neville, 1996, Cardiovascular research.

Hypoxic pulmonary vasoconstriction.

L. Shimoda, P. Aaronson, J. Ward, 2012, Physiological Reviews.