D. Roerig

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First Pass Uptake of Fentanyl, Meperidine, and Morphine in the Human Lung

C A Dawson, J. Kampine, C. Dawson, 1987, Anesthesiology.

special communication Pulmonary arterial morphometry from microfocal X-ray computed tomography

C. Dawson, C. Hanger, Roger H. Johnson, 2001 .

Microfocal X-ray CT imaging and pulmonary arterial distensibility in excised rat lungs.

Anita H. Dhyani, S T Haworth, C A Dawson, 2001, American journal of physiology. Heart and circulatory physiology.

Lung Tissue Mitochondrial Benzodiazepine Receptors Increase in a Model of Pulmonary Inflammation

C. Dawson, D. Roerig, S. Ahlf, 2002, Lung.

Extracellular perfusion of rat brain nuclei using microdialysis: a method for studying differential neurotransmitter release in response to neurotoxins.

N. Reynolds, D. Roerig, W. Lin, 1999, Brain research. Brain research protocols.

Effects of l-Arginine and Nω-Nitro-l-Arginine Methyl Ester on Cardiac Perfusion and Function After 1-Day Cold Preservation of Isolated Hearts

Z. Bosnjak, M. Boban, D. Stowe, 1997 .

Coenzyme Q1 redox metabolism during passage through the rat pulmonary circulation and the effect of hyperoxia.

G. Krenz, D. Roerig, S. Audi, 2008, Journal of applied physiology.

Pulmonary disposition of lipophilic amine compounds in the isolated perfused rabbit lung.

C. Dawson, J. Linehan, G. Krenz, 1998, Journal of applied physiology.

Effect of chronic hyperoxic exposure on duroquinone reduction in adult rat lungs.

G. Krenz, D. Roerig, S. Haworth, 2005, American journal of physiology. Lung cellular and molecular physiology.

HIGHLIGHTED TOPIC Imaging Lung Physiology Role of glutathione in lung retention of 99m Tc-hexamethylpropyleneamine oxime in two unique rat models of hyperoxic lung injury

A. Clough, D. Roerig, S. Haworth, 2012 .

Clonidine reduces sympathetic activity but maintains baroreflex responses in normotensive humans.

J. Kampine, D. Roerig, T. Ebert, 1992, Anesthesiology.

Distribution of Capillary Transit Times in Isolated Lungs of Oxygen-Tolerant Rats

A. Clough, R. Molthen, D. Roerig, 2010, Annals of Biomedical Engineering.

Pulmonary Endothelial Surface Reductase Kinetics

C. Dawson, J. Linehan, G. Krenz, 1998 .

Airway responses to esophageal acidification.

R. Shaker, H. Forster, I. Lang, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Mediation of reduced nicotinamide adenine dinucleotide phosphate dependent reduction of cytochrome c by morphine.

D. Roerig, R. Wang, R. I. Wang, 1974, Biochemical pharmacology.

Proline in vasoactive peptides: consequences for peptide hydrolysis in the lung.

C. Dawson, K. Nithipatikom, D. Roerig, 1999, American journal of physiology. Lung cellular and molecular physiology.

Pulmonary P-450-mediated eicosanoid metabolism and regulation in the pregnant rabbit.

P. Ortiz de Montellano, B. Masters, R. Murphy, 1989, Advances in prostaglandin, thromboxane, and leukotriene research.

In vivo detection of hyperoxia-induced pulmonary endothelial cell death using (99m)Tc-duramycin.

A. Clough, E. Jacobs, D. Roerig, 2015, Nuclear medicine and biology.

Suppression of clinical weakness in experimental autoimmune encephalomyelitis associated with weight changes, and post-decapitation convulsions after intracisternal-ventricular administration of 6-hydroxydopamine

W. Karpus, D. Roerig, U. Wesselmann, 1990, Journal of Neuroimmunology.

Proline in vasoactive peptides : consequences for peptide hydrolysis in the lung

C. Dawson, K. Nithipatikom, D. Roerig, 1999 .

Angiotensin-converting enzyme preferentially hydrolyzes trans isomer of proline-containing substrate.

C. Dawson, J. Linehan, D. Roerig, 1993, Journal of applied physiology.

Effect of transit time on metabolism of a pulmonary endothelial enzyme substrate.

C. Dawson, J. Linehan, D. Roerig, 1989, The American journal of physiology.

Plasma protein binding and endothelial enzyme interactions in the lung.

T. A. Bronikowski, C. Dawson, J. Linehan, 1989, Journal of applied physiology.

Omega-hydroxylation of prostaglandin E1 in the isolated perfused lungs of pregnant rabbits.

B. Masters, R. Okita, D. Roerig, 1988, Prostaglandins.

Effect of propranolol on the first pass uptake of fentanyl in the human and rat lung.

J. Kampine, C. Dawson, D. Roerig, 1989, Anesthesiology.

Oral dexmedetomidine attenuates hemodynamic responses during emergence from general anesthesia in chronically instrumented dogs.

J. Kampine, D. Warltier, W. Schmeling, 1991, Anesthesiology.

AHEART January 47/1

M. L. Schulte, C. Dawson, D. Roerig, 1999 .

Duroquinone reduction during passage through the pulmonary circulation.

C. Dawson, D. Roerig, S. Audi, 2003, American journal of physiology. Lung cellular and molecular physiology.

Epidural Sufentanil Infusion for Postoperative Analgesia

D. Roerig, E. Cheng, R. Stevens, 1995 .

Chronic Verapamil Treatment Depresses Automaticity and Contractility in Isolated Cardiac Tissues

Z. Bosnjak, J. Kampine, D. Stowe, 1991, Anesthesia and Analgesia.

FIRST PASS UPTAKE OF LIDOCAINE, DIAZEPAM AND THIOPENTAL IN THE HUMAN LUNG

J. Kampine, D. Roerig, K. Kotrly, 1988 .

Oxygen dependency of monoamine oxidase activity in the intact lung.

C. Dawson, D. Roerig, S. Ahlf, 2001, American journal of physiology. Lung cellular and molecular physiology.

Methods of identification and confirmation of abusive drugs in human urine.

D. Roerig, M. Mueller, R. Wang, 1975, Journal of chromatography.

Evidence for superoxide generation by NADPH-cytochrome c reductase of rat liver microsomes.

S. Aust, D. Roerig, T. Pederson, 1972, Biochemical and biophysical research communications.

Pulmonary endothelial thiazine uptake: separation of cell surface reduction from intracellular reoxidation.

C. Dawson, J. Linehan, D. Výprachtický, 1997, The American journal of physiology.

Reduction of thiazine dyes by bovine pulmonary arterial endothelial cells in culture.

C. Dawson, J. Linehan, D. Roerig, 1995, The American journal of physiology.

Dexmedetomidine Alters the Hemodynamic Effects of Desflurane and Isoflurane in Chronically Instrumented Dogs

P. Pagel, J. Kersten, W. Schmeling, 1993, Anesthesiology.

Enzymatic conversion of morphine to pseudomorphine.

D. Roerig, R. Wang, C. J. Reak, 1976, Biochemical pharmacology.

Peroxidase-catalyzed irreversible binding of morphine to protein.

D. Roerig, R. Wang, M. J. Deutsch, 1977, Biochemical pharmacology.

The effects of the stereoisomers of the alpha 2-adrenergic agonist medetomidine on systemic and coronary hemodynamics in conscious dogs.

J. Kampine, D. Warltier, W. Schmeling, 1991, Anesthesiology.

Differential Lung Uptake of 99mTc-Hexamethylpropyleneamine Oxime and 99mTc-Duramycin in the Chronic Hyperoxia Rat Model

A. Clough, D. Roerig, S. Haworth, 2012, The Journal of Nuclear Medicine.

Differential responses of targeted lung redox enzymes to rat exposure to 60 or 85% oxygen.

A. Clough, D. Roerig, S. Audi, 2011, Journal of applied physiology.

Toluidine blue O and methylene blue as endothelial redox probes in the intact lung.

M. L. Schulte, C. Dawson, L. Olson, 2000, American journal of physiology. Heart and circulatory physiology.

Improvement in functional recovery of the isolated guinea pig heart after hyperkalemic reperfusion with adenosine.

Z. Bosnjak, B. Graf, D. Stowe, 1996, The Journal of thoracic and cardiovascular surgery.

BEAT-BY-BEAT CARDIOVASCULAR RESPONSES TO RAPID SEQUENCE INDUCTION IN HUMANSEFFECTS OF LABETALOL

M. Nelson, D. Roerig, T. Ebert, 1987 .

Attenuation of hemodynamic responses to rapid sequence induction and intubation in healthy patients with a single bolus of esmolol.

J. Kampine, D. Stowe, D. Roerig, 1990, Journal of clinical anesthesia.

Effects of Halo thane on Acetylcholine Release and Sympathetic Ganglionic Transmission

J. Kampine, Z. Dujic, D. Roerig, 1986, Anesthesiology.

The effects of morphine on sympathetic transmission in the stellate ganglion of the cat.

Z. Bosnjak, J. Kampine, J. Seagard, 1986, Canadian Journal of Physiology and Pharmacology.

Halothane Reduces Release of Adenosine, Inosine, and Lactate with Ischemia and Reperfusion in Isolated Hearts

Z. Bosnjak, J. Kampine, D. Stowe, 1993, Anesthesia and analgesia.

Volatile Anesthetics Do Not Alter Bradykinin‐induced Release of Nitric Oxide or L‐Citrulline in Crystalloid Perfused Guinea Pig Hearts

Z. Bosnjak, D. Stowe, D. Roerig, 1998, Anesthesiology.

First‐Pass Uptake of Verapamil, Diazepam, and Thiopental in the Human Lung

C A Dawson, J. Kampine, C. Dawson, 1989, Anesthesia and analgesia.

Effects of fentanyl-diazepam-nitrous oxide anaesthesia on arterial baroreflex control of heart rate in man.

J. Kampine, D. Roerig, K. Kotrly, 1986, British journal of anaesthesia.

Uptake and efflux of 1-alpha-acetylmethadol (LAAM) and methadone in the isolated perfused rat lung.

C. Dawson, D. Roerig, R. I. Wang, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung.

K. Olson, D. Roerig, S. Ahlf, 2012, Journal of applied physiology.

KINETIC CHARACTERIZATION OF P-GLYCOPROTEIN-MEDIATED EFFLUX OF RHODAMINE 6G IN THE INTACT RABBIT LUNG

D. Roerig, S. Ahlf, S. Audi, 2004, Drug Metabolism and Disposition.

OF P-GLYCOPROTEIN-MEDIATED EFFLUX OF RHODAMINE 6 G IN THE INTACT RABBIT LUNG

D. Roerig, S. Ahlf, S. Audi, 2004 .

Microsomal electron transport: tetrazolium reduction by rat liver microsomal NADPH-cytochrome c reductase.

S. Aust, D. Roerig, L. Mascaro, 1972, Archives of biochemistry and biophysics.

Effect of chloroquine and phenobarbital on morphine glucuronidation and biliary excretion in the rat.

R. Peterson, D. Roerig, A. Hasegawa, 1974, Biochemical pharmacology.

Effect of phenobarbital pretreatment on the metabolism and biliary excretion of methadone.

D. Roerig, A. Hasegawa, R. I. Wang, 1975, Biochemical pharmacology.

First pass uptake in the human lung of drugs used during anesthesia.

J. Kampine, C. Dawson, J. Linehan, 1994, Advances in pharmacology.

Transit time dispersion in the pulmonary arterial tree.

A. Clough, C. Dawson, J. Linehan, 1998, Journal of applied physiology.

Endothelium and Compound Transfer

C. Dawson, G. Krenz, D. Roerig, 2003 .

Comparison of radioimmunoassay with thin-layer chromatographic and gas-liquid chromatographic methods of barbiturate detection in human urine.

D. Roerig, M. Mueller, D. Lewand, 1975, Clinical chemistry.

Differential responses of extracellular GABA to intrastriatal perfusions of 3-nitropropionic acid and quinolinic acid in the rat

N. Reynolds, D. Roerig, C. M. Cameron, 1997, Brain Research.

Brain and plasma levels of methadone and their relationships to analgesic activity of methadone in rats.

D. Roerig, S. J. Liu, R. I. Wang, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Altered splenic catecholamine concentrations during experimental allergic encephalomyelitis

D. Harder, D. Roerig, U. Wesselmann, 1987, Pharmacology Biochemistry and Behavior.

Evaluation of endothelial injury in the human lung.

C. Dawson, J. Linehan, D. Roerig, 1989, Clinics in chest medicine.

Early effects of experimental diabetes on central catecholamine concentrations

D. Harder, D. Roerig, U. Wesselmann, 1988, Brain Research Bulletin.

An interpretation of14C-urea and14C-primidone extraction in isolated rabbit lungs

C. Dawson, J. Linehan, G. Krenz, 1996, Annals of Biomedical Engineering.

DUROQUINONE REDUCTIO N DURING PASSAGE THR OUGH THE PULMONARY CIRCUL ATION

D. Roerig, S. Audi, R. Bongard, 2003 .

Pulmonary reduction of an intravascular redox polymer.

C. Dawson, D. Roerig, S. Audi, 2001, American journal of physiology. Lung cellular and molecular physiology.

Estimation of the pulmonary capillary transport function in isolated rabbit lungs.

C. Dawson, J. Linehan, G. Krenz, 1995, Journal of applied physiology.

Reduction and accumulation of methylene blue by the lung.

C. Dawson, J. Linehan, G. Krenz, 1994, Journal of applied physiology.

Role of glutathione in lung retention of 99mTc-hexamethylpropyleneamine oxime in two unique rat models of hyperoxic lung injury.

A. Clough, D. Roerig, S. Haworth, 2012, Journal of applied physiology.

Pulmonary inflammation alters the lung disposition of lipophilic amine indicators.

C. Dawson, D. Roerig, S. Ahlf, 1999, Journal of applied physiology.

Enterohepatic circulation of l-alpha-acetylmethadol in the rat.

D. Roerig, A. Hasegawa, R. I. Wang, 1980, The Journal of pharmacology and experimental therapeutics.

Role of enterohepatic circulation in the analgesic action of 1-alpha-acetylmethadol in the rat.

D. Roerig, A. Hasegawa, R. I. Wang, 1979, Drug metabolism and disposition: the biological fate of chemicals.

Effect of alteration of metabolism on the analgesic activity, toxicity, distribution and excretion of l-alpha-acetylmethadol in the rat.

D. Roerig, A. Hasegawa, R. I. Wang, 1977, The Journal of pharmacology and experimental therapeutics.

Role of metabolism in the biliary excretion of methadone metabolites.

D. Roerig, A. Hasegawa, R. I. Wang, 1976, The Journal of pharmacology and experimental therapeutics.

Quantification of bronchial circulation perfusion in rats

Anne V. Clough, Robert C. Molthen, Steven T. Haworth, 2004, SPIE Medical Imaging.

Occurrence of corneal opacities in rats after acute administration of l-?-acetylmethadol

D. Roerig, K. Lynch, G. Harris, 1980 .

Lipophilic Amines as Probes for Measurement of Lung Capillary Transport Function and Tissue Composition Using the Multiple-Indicator Dilution Method

C. Dawson, J. Linehan, G. Krenz, 1998 .

Bronchial circulation angiogenesis in the rat quantified with SPECT and micro-CT

Anne V. Clough, Robert C. Molthen, Steven T. Haworth, 2008, European Journal of Nuclear Medicine and Molecular Imaging.

the isolated perfused rabbit lung Pulmonary disposition of lipophilic amine compounds in

C. Dawson, J. Linehan, G. Krenz, 2015 .

Pulmonary arterial morphometry from microfocal X-ray computed tomography.

Anita H. Dhyani, S T Haworth, C A Dawson, 2001, American journal of physiology. Heart and circulatory physiology.

Radioimmunuassay compared to thin-layer and gas--liquid chromatography for detecting methadone in human urine.

D. Roerig, M. M. Mueller, D. Lewand, 1976, Clinical chemistry.

Uptake of l-alpha-acetylmethadol (LAAM) and its analgesically active metabolites, nor-LAAM and dinor-LAAM, in the isolated perfused rat lung.

C. Dawson, D. Roerig, R. Dahl, 1983, Drug metabolism and disposition: the biological fate of chemicals.

to rat exposure to 60 or 85% oxygen Differential responses of targeted lung redox enzymes

A. Clough, D. Roerig, S. Haworth, 2015 .

Role of glutathione in lung retention of 99mTc-hexamethylpropyleneamine oxime in two unique rat models of hyperoxic lung injury.

A. Clough, D. Roerig, S. Haworth, 2012, Journal of applied physiology.

SPECT/Micro-CT Imaging of Bronchial Angiogenesis in a Rat

A. Clough, R. Molthen, C. Wietholt, 2005 .

Detection of changes in lung tissue properties with multiple-indicator dilution.

C. Dawson, J. Linehan, G. Krenz, 1999, Journal of applied physiology.

Transit time dispersion in the pulmonary arterial tree.

A. Clough, C. Dawson, J. Linehan, 1998, Journal of applied physiology.

Pulmonary Arterial Morphometry from Microfocal X-Ray Pulmonary Arterial Morphometry from Microfocal X-Ray Computed Tomography Computed Tomography

Anita H. Dhyani, D. Roerig, S. Haworth, 2023 .

Distribution of Capillary Transit Times in Isolated Lungs of Distribution of Capillary Transit Times in Isolated Lungs of Oxygen-Tolerant Rats Oxygen-Tolerant Rats

A. Clough, D. Roerig, S. Audi, 2022 .

Lung angiotensin-converting enzyme kinetics from indicator-dilution and constant-infusion methods.

T. A. Bronikowski, C. Dawson, J. Linehan, 1990, The American journal of physiology.