R. van der Nagel

发表

Peroxisome Proliferator-activated Receptor (PPAR) Gene Profiling Uncovers Insulin-like Growth Factor-1 as a PPARα Target Gene in Cardioprotection*

L. D. de Windt, M. van Bilsen, H. el Azzouzi, 2011, The Journal of Biological Chemistry.

Beat-to-Beat Variability in Preload Unmasks Latent Risk of Torsade de Pointes in Anesthetized Chronic Atrioventricular Block Dogs.

M. Vos, H. V. van Rijen, M. A. van der Heyden, 2016, Circulation journal : official journal of the Japanese Circulation Society.

Reduced Cx43 Expression Triggers Increased Fibrosis Due to Enhanced Fibroblast Activity

Jacques M T de Bakker, Harold V M van Rijen, Tri Q Nguyen, 2012, Circulation. Arrhythmia and electrophysiology.

Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absent.

Mark E. Anderson, K. Kamiya, M. Vos, 2016, Cardiovascular research.

Ventricular remodelling is a prerequisite for the induction of dofetilide-induced torsade de pointes arrhythmias in the anaesthetized, complete atrio-ventricular-block dog.

M. Vos, P. Oosterhoff, R. van der Nagel, 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy

I. van der Made, E. Creemers, P. Postema, 2018, European heart journal.

NFATc2 Is a Necessary Mediator of Calcineurin-dependent Cardiac Hypertrophy and Heart Failure*

X. Wehrens, L. D. de Windt, S. Heeneman, 2008, Journal of Biological Chemistry.

EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.

P. Doevendans, S. Ackerman, H. V. van Rijen, 2006, Journal of the American College of Cardiology.

Anesthesia and Arrhythmogenesis in the Chronic Atrioventricular Block Dog Model

M. Vos, M. A. van der Heyden, P. Oosterhoff, 2010, Journal of cardiovascular pharmacology.

β-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation

J. Balligand, R. Dietz, L. D. de Windt, 2008, Proceedings of the National Academy of Sciences.

Downregulation of Apoptosis-Inducing Factor in Harlequin Mutant Mice Sensitizes the Myocardium to Oxidative Stress–Related Cell Death and Pressure Overload–Induced Decompensation

P. Doevendans, S. Ackerman, V. V. van Empel, 2005, Circulation research.

NF-kappaB activation is required for adaptive cardiac hypertrophy.

R. Dietz, L. D. de Windt, M. Bergmann, 2009, Cardiovascular research.

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction

E. Olson, E. van Rooij, R. Bassel-Duby, 2007, Proceedings of the National Academy of Sciences.

Combined Na+/Ca2+ Exchanger and L-Type Calcium Channel Block as a Potential Strategy to Suppress Arrhythmias and Maintain Ventricular Function

K. Sipido, M. Vos, T. V. van Veen, 2013, Circulation. Arrhythmia and electrophysiology.

Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice.

J. D. de Bakker, M. Vos, T. V. van Veen, 2012, Heart rhythm.

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.

W. Birchmeier, T. V. van Veen, H. V. van Rijen, 2012, Cardiovascular research.

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure.

S. Reiken, A. Marks, S. Lehnart, 2005, Proceedings of the National Academy of Sciences of the United States of America.

MEF2 Activates a Genetic Program Promoting Chamber Dilation and Contractile Dysfunction in Calcineurin-Induced Heart Failure

P. Doevendans, E. van Rooij, L. D. de Windt, 2006, Circulation.

Combined reduction of intercellular coupling and membrane excitability differentially affects transverse and longitudinal cardiac conduction.

Jacques M T de Bakker, Harold V M van Rijen, R. Hauer, 2009, Cardiovascular research.

In calcineurin-induced cardiac hypertrophy expression of Nav1.5, Cx40 and Cx43 is reduced by different mechanisms.

M. Vos, T. V. van Veen, H. V. van Rijen, 2008, Journal of molecular and cellular cardiology.

Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress

J. D. de Bakker, M. Vos, T. V. van Veen, 2019, International journal of molecular sciences.

Comparison of the IKr blockers moxifloxacin, dofetilide and E‐4031 in five screening models of pro‐arrhythmia reveals lack of specificity of isolated cardiomyocytes

G Duker, P. Sartipy, M. Peschar, 2012, British journal of pharmacology.

Changes in Cx43 and NaV1.5 Expression Precede the Occurrence of Substantial Fibrosis in Calcineurin-Induced Murine Cardiac Hypertrophy

M. Vos, H. V. van Rijen, M. Fontes, 2014, PloS one.

Reduced Cx43 Expression Triggers Increased Fibrosis Due to Enhanced Fibroblast Activity

J. D. de Bakker, M. Vos, T. V. van Veen, 2012, Circulation. Arrhythmia and electrophysiology.

Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.

K. Sipido, M. Vos, T. V. van Veen, 2012, Heart rhythm.

Ventricular remodelling is a prerequisite for the induction of dofetilide-induced torsade de pointes arrhythmias in the anaesthetized, complete atrio-ventricular-block dog.

Anesthesia and Arrhythmogenesis in the Chronic Atrioventricular Block Dog Model

M. Vos, P. Oosterhoff, R. van der Nagel, 2010, Journal of cardiovascular pharmacology.