A. Varma

发表

Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

Suranjana Das, Ashok K. Varma, Rohan Patil, 2010, PloS one.

Structural and biophysical properties of h-FANCI ARM repeat protein

Nikhil Gadewal, A. Varma, H. Misra, 2017, Journal of biomolecular structure & dynamics.

Over-expression, purification and isotopic labeling of a tag-less human glucose-dependent insulinotropic polypeptide (hGIP)

Vikrant, J. D'Souza, E. Coutinho, 2013, 3 Biotech.

Exome sequencing study of Russian breast cancer patients suggests a predisposing role for USP39

T. Dörk, E. Khusnutdinova, N. Bogdanova, 2019, Breast Cancer Research and Treatment.

Structureomics in Systems-Based Drug Discovery

A. Varma, Pankaj S. Thapa, L. Yadav, 2016 .

Validation of Different Systems for Tumstatin Expression and its in-vitro and iv-vivo Activities.

C. Boosani, A. Sudhakar, A. Varma, 2009, Journal of cancer science & therapy.

A novel loop domain in superantigens extends their T cell receptor recognition site.

R. Mariuzza, B. Moza, A. Rahman, 2007, Journal of molecular biology.

Crystal structure of clinically reported mutations Gly656Arg, Gly656Glu and Asp751His identified in the kinase domain of EphA7.

A. Varma, Shubhashish Chakraborty, S. Chakraborty, 2021, Biochemical and biophysical research communications.

Pathogenicity of Mutations Discovered in BRCA1 BRCT Domains is Characterized by Destabilizing the Hydrophobic Interactions

Nikhil Gadewal, A. Varma, D. Badgujar, 2012 .

The in Silico Approach to Identify a Unique Plant-Derived Inhibitor Against E6 and E7 Oncogenic Proteins of High-Risk Human Papillomavirus 16 and 18

Lingaraja Jena, A. Varma, Satish Kumar, 2016 .

Quantitative Serum Proteomics Reveals The Predictive and Prognostic Potential of Clusterin and Gelsolin in Head and Neck Squamous Cell Carcinoma Treated With Radiotherapy

V. Murthy, A. Varma, Lipi Das, 2021 .

Role of MERIT40 in stabilization of BRCA1 complex: a protein-protein interaction study.

Vikrant, A. Varma, Ulka Sawant, 2014, Biochemical and biophysical research communications.

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

A. Varma, J. Ladias, G. Birrane, 2005, Biochemistry.

Structural basis to characterise transactivation domain of BRCA1

N. S. Kumar, A. Varma, M. Hosur, 2017, Journal of biomolecular structure & dynamics.

Tetrameric ZBRK1 DNA binding domain has affinity towards cognate DNA in absence of zinc ions.

Vikrant, A. Varma, M. Hosur, 2014, Biochemical and biophysical research communications.

Functional assessment of intrinsic disorder central domains of BRCA1

A. Varma, M. Hosur, L. Yadav, 2015, Journal of biomolecular structure & dynamics.

Preliminary crystallographic studies of BRCA1 BRCT-ABRAXAS complex.

A. Varma, M. Hosur, L. Yadav, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Multimodal approach to characterize the tetrameric form of human PML-RBCC domain and ATO-mediated conformational changes.

A. Varma, M. Q. Siddiqui, N. Goswami, 2022, International journal of biological macromolecules.

In silico and structure-based assessment to classify VUS identified in the α-helical domain of BRCA2

A. Varma, M. Khan, 2022, Journal of biomolecular structure & dynamics.

Absence of High Penetrance Genes Mutations in Familial Breast Cancer in Mizo-Mongloid Population, Northeast India

N. S. Kumar, A. Varma, R. Muthukumaran, 2020 .

Sulfinyl Group as an Intramolecular Nucleophile: Synthesis of Bromohydrins from β-Methyl-γ,δ-unsaturated Sulfoxides with High 1,2-Asymmetric Induction†

A. Nangia, A. Varma, S. Raghavan, 2002 .

In Silico Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18

Lingaraja Jena, A. Varma, Satish Kumar, 2015, Genomics & informatics.

Virtual Screening for Potential Inhibitors of High-Risk Human Papillomavirus 16 E6 Protein

Lingaraja Jena, A. Varma, Satish Kumar, 2015, Interdisciplinary Sciences Computational Life Sciences.

Evaluation of conformational transitions of h-BRCA2 functional domain and unclassified variant Arg2502Cys using multimodal approach.

A. Varma, M. Q. Siddiqui, E. Kuligina, 2022, International journal of biological macromolecules.

Structural basis of T‐cell specificity and activation by the bacterial superantigen TSST‐1

K. Wucherpfennig, B. Moza, Rebecca A Buonpane, 2007, The EMBO journal.

Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain

N. S. Kumar, Nikhil Gadewal, A. Varma, 2018, RSC advances.

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis

Lingaraja Jena, A. Varma, Satish Kumar, 2014, Genomics & informatics.

Molecular Docking Explains Atomic Interaction between Plant-originated Ligands and Oncogenic E7 Protein of High Risk Human Papillomavirus Type 16

Lingaraja Jena, A. Varma, Satish Kumar, 2014 .

Comprehensive Analysis of Low Molecular Weight Serum Proteome Enrichment for Mass Spectrometric Studies

V. Murthy, A. Varma, Lipi Das, 2020, ACS omega.

Targeting Pim-1 kinase for potential drug-development

Ashok Varma, Nikhil Gadewal, Nikhil Gadewal, 2012, Int. J. Comput. Biol. Drug Des..

Molecular Modeling of Differentially Phosphorylated Serine 10 and Acetylated lysine 9/14 of Histone H3 Regulates their Interactions with 14-3-3ζ, MSK1, and MKP1

Sanjay Gupta, Nikhil Gadewal, A. Varma, 2013, Bioinformatics and biology insights.

Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human—Ribosomal S6 Kinases-3

Nikhil Gadewal, A. Varma, M. Hosur, 2016, Cell Biochemistry and Biophysics.

Genetic ablation of pregnancy zone protein promotes breast cancer progression by activating TGF-β/SMAD signaling

A. Sokolenko, Sudeep Gupta, A. Varma, 2020, Breast Cancer Research and Treatment.

In Silico-Based Structural Evaluation to Categorize the Pathogenicity of Mutations Identified in the RAD Class of Proteins

A. Varma, R. Baruah, Aaliya Anwaar, 2023, ACS omega.

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50

S. Nachimuthu, Nikhil Gadewal, A. Varma, 2017, Scientific Reports.

Multimodal approach to explore the pathogenicity of BARD1, ARG 658 CYS, and ILE 738 VAL mutants

Vikrant, N. S. Kumar, Nikhil Gadewal, 2016, Journal of biomolecular structure & dynamics.

Crystal structure of the BARD1 BRCT domains.

A. Varma, J. Ladias, G. Birrane, 2007, Biochemistry.

Structural and functional characterization of the MERIT40 to understand its role in DNA repair

Vikrant, R. Sarma, A. Varma, 2014, Journal of biomolecular structure & dynamics.

Mislocalization of BRCA1-complex due to ABRAXAS Arg361Gln mutation

Vikrant, Nalini Singh, R. Sarma, 2015, Journal of biomolecular structure & dynamics.

Structural and Functional Implication of RAP80 ΔGlu81 Mutation

Vikrant, M. Massiah, A. Varma, 2013, PloS one.

Phosphorylation of deinococcal RecA affects its structural and functional dynamics implicated for its roles in radioresistance of Deinococcus radiodurans

D. Sharma, Nikhil Gadewal, A. Varma, 2020, Journal of biomolecular structure & dynamics.

Hydrogen bonding in two tetracyclic indole alkaloids.

G. Desiraju, A. Nangia, P. Jaisankar, 2001, Acta crystallographica. Section C, Crystal structure communications.

Genetic ablation of pregnancy zone protein promotes breast cancer progression by activating TGF-β/SMAD signaling

A. Sokolenko, Sudeep Gupta, A. Varma, 2020, Breast Cancer Research and Treatment.

miRNA–mRNA Profiling Reveals Prognostic Impact of SMC1A Expression in Acute Myeloid Leukemia

Nikhil Gadewal, A. Varma, S. Hasan, 2020, Oncology research.

In Silico and Structure-Based Assessment of Similar Variants Discovered in Tandem Repeats of BRCT Domains of BRCA1 and BARD1 To Characterize the Folding Pattern

A. Varma, Ulka Sawant, Neha Mishra, 2022, ACS omega.

In silico structural analysis of secretory clusterin to assess pathogenicity of mutations identified in the evolutionarily conserved regions

S. Shekhar, P. Chandrani, A. Varma, 2021, Journal of biomolecular structure & dynamics.

Virtual Screening for Potential Inhibitors of High-Risk Human Papillomavirus 16 E6 Protein

Lingaraja Jena, A. Varma, Satish Kumar, 2015, Interdisciplinary Sciences: Computational Life Sciences.

Breast Cancer Is Significantly Associated with Cancers in The First- and Second-Degree Relatives in Ethnic Mizo-Mongoloid Population, Northeast India

N. Senthil Kumar, A. Varma, R. Muthukumaran, 2022, National Journal of Community Medicine.

Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens.

C. Herfst, A. Rahman, J. McCormick, 2007, Journal of molecular biology.

Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human—Ribosomal S6 Kinases-3

Nikhil Gadewal, A. Varma, M. Hosur, 2016, Cell Biochemistry and Biophysics.

Structural dynamics of clinically-reported VUS in the BARD1 ARD-BRCT region to predict the molecular basis of alterations.

A. Varma, R. Choudhary, Neha Mishra, 2023, Journal of biomolecular structure & dynamics.

hpvPDB: An Online Proteome Reserve for Human Papillomavirus

Satish Kumar, Lingaraja Jena, Sangeeta Daf, 2013, Genomics & informatics.

Evaluation of Pathogenicity and Structural Alterations for the Mutations Identified in the Conserved Region of the C-Terminal Kinase Domain of Human-Ribosomal S6 Kinase 1

A. Varma, P. Borah, M. Khan, 2023, ACS omega.

Virtual screening for potential inhibitors of high-risk human papillomavirus 16 E6 protein.

Lingaraja Jena, A. Varma, Satish Kumar, 2015, Interdisciplinary Sciences Computational Life Sciences.

Structural basis of T‐cell specificity and activation by the bacterial superantigen TSST‐1

K. Wucherpfennig, B. Moza, Rebecca A Buonpane, 2007, The EMBO journal.

Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism.

Nikhil Gadewal, A. Varma, H. Misra, 2017, International journal of biological macromolecules.

Virtual Screening for Potential Inhibitors of High-Risk Human Papillomavirus 16 E6 Protein

Lingaraja Jena, A. Varma, Satish Kumar, 2015, Interdisciplinary Sciences: Computational Life Sciences.