W. Adams

发表

Synthesis and bioactivity of novel bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships and increased metabolic stability of novel substituted pyridine analogs.

L. Kopta, R. Olmsted, D. Romero, 1996, Journal of medicinal chemistry.

Studies of Aβ Pharmacodynamics in the Brain, Cerebrospinal Fluid, and Plasma in Young (Plaque-Free) Tg2576 Mice Using the γ-Secretase Inhibitor N2-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY-411575)

T. Lanz, K. Merchant, W. Adams, 2004, Journal of Pharmacology and Experimental Therapeutics.

Electron diffraction study of the structure and internal rotation of cyclobutanecarboxylic acid chloride

L. Bartell, W. Adams, 1971 .

Structure and vibrational assignments for PCl5: An electron diffraction study

L. Bartell, W. Adams, 1971 .

ARRANGEMENT IN THE JAWS OF THE ROOTS OF THE TEETH.

W. T. Dempster, W. Adams, R. Duddles, 1963, Journal of the American Dental Association.

Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans.

G. S. Hughes, E. Antal, W. Adams, 1996, Critical care medicine.

Pharmacokinetics of intravenously administered cefmetazole and cefoxitin and effects of probenecid on cefmetazole elimination

W. Adams, G. Peters, H. Ko, 1989, Antimicrobial Agents and Chemotherapy.

MSDC-0602K, a metabolic modulator directed at the core pathology of non-alcoholic steatohepatitis

J. Colca, W. Adams, W. G. McDonald, 2018, Expert opinion on investigational drugs.

Mechanistic studies of the metabolic chiral inversion of (R)-ibuprofen in humans.

T. Baillie, W. Adams, L. Olanoff, 1989, The Journal of pharmacology and experimental therapeutics.

(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.

W. L. White, R. Nugent, L. Kopta, 1998, Journal of medicinal chemistry.

HPLC and flow cytometric analyses of uptake of adriamycin and menogaril by monolayers and multicell spheroids.

E. G. Adams, W. Adams, B. Bhuyan, 1990, Selective cancer therapeutics.

Metabolic chiral inversion of flurbiprofen-CoA in vitro.

T. Baillie, S. M. Sanins, W. Adams, 1991, Biochemical pharmacology.

Influence of H2 Receptor Antagonists on the Disposition of Flurbiprofen Enantiomers

S. Cox, W. Adams, Ralph E. Small PharmD, 1990, Journal of clinical pharmacology.

Determination of glyburide in human serum by liquid chromatography with fluorescence detection.

W. Adams, M. Courtney, J. Brewer, 1982, Analytical chemistry.

The Metabolic Background

W. Adams, 2020, Early Phase Drug Evaluation in Man.

Specific and Sensitive High Performance Liquid Chromatographic Determination of Alprazolam or Triazolam

W. Adams, 1979 .

349. Nitrosoacylarylamines. Part V. The nitrosation of 3-acetamido-4-quinolones and -quinaldones

W. Adams, D. Hey, 1951 .

New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones.

D. Patel, C. Hackbarth, Zhengyu Yuan, 2003, Bioorganic & medicinal chemistry letters.

Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.

L. Wienkers, Joel Morris, W. Watt, 2003, Journal of medicinal chemistry.

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones.

W. Watt, M. Genin, J. M. Friis, 2003, Bioorganic & medicinal chemistry letters.

Nitrogen-carbon-linked (azolylphenyl)oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.

M. Genin, J. M. Friis, W. Adams, 1998, Journal of medicinal chemistry.

A Study of the Ferric-Tartrate Complex in Alkaline Solution

W. Adams, 2020 .

Structure and conformation of 1,3-dithlane: an electron diffraction study

L. Bartell, W. Adams, 1977 .

Structure, equilibrium conformation, and pseudorotation in cyclopentane. An electron diffraction study

Herman J. Geise, L. Bartell, H. Geise, 1970 .

Structure, Pseudorotation, and Vibrational Mode Coupling in IF7: An Electron Diffraction Study

H. Bradford Thompson, L. Bartell, Lawrence S. Bartell, 1970 .

Electron diffraction study of gaseous tetrahydrofuran

H. J. Geise, L. Bartell, H. Geise, 1969 .

Pharmacokinetics of single-dose cefmetazole following intramuscular administration of cefmetazole sodium to healthy male volunteers

W. Adams, E. Novak, J. Hosley, 1989, Antimicrobial Agents and Chemotherapy.

A review of cement–superplasticizer interactions and their models

Robert Schennach, D. Cocke, David L. Cocke, 2000 .

Mechanistic studies on the metabolic chiral inversion of R-ibuprofen in the rat.

T. Baillie, S. M. Sanins, W. Adams, 1991, Drug metabolism and disposition: the biological fate of chemicals.

Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.

Joel Morris, D. B. Evans, S. Sharma, 1996, Journal of medicinal chemistry.

Simple, rapid and sensitive high-performance liquid chromatographic determination of delavirdine and its N-desisopropyl metabolite in human plasma.

M. G. Johnson, J. M. Friis, W. Adams, 1995, Journal of chromatography. B, Biomedical applications.

Preclinical and Clinical Evidence for the Collaborative Transport and Renal Secretion of an Oxazolidinone Antibiotic by Organic Anion Transporter 3 (OAT3/SLC22A8) and Multidrug and Toxin Extrusion Protein 1 (MATE1/SLC47A1)

Jeffrey C Stevens, Yurong Lai, J. Stevens, 2010, Journal of Pharmacology and Experimental Therapeutics.

Discovery and development of the BHAP nonnucleoside reverse transcriptase inhibitor delavirdine mesylate.

R. Jensen, D. Romero, W. Morozowich, 1998, Pharmaceutical biotechnology.

Quantitation of anthracycline antitumor agent menogarol in plasma using liquid chromatography with fluorescence detection.

R. D. Hamilton, W. Adams, J. Mcgovren, 1984, Analytical chemistry.

Clinical Proof-of-Concept Study With MSDC-0160, a Prototype mTOT-Modulating Insulin Sensitizer

D. Orloff, J. Colca, W. Adams, 2013, Clinical pharmacology and therapeutics.

Dimethyl Sulfoxide as a Solvent for the Lossen Rearrangement

W. Adams, D. Berndt, 1966 .

Specific and sensitive high-performance liquid chromatographic determination of glyburide.

W. Adams, D. S. Krueger, 1979, Journal of pharmaceutical sciences.

High Performance Liquid Chromatographic Determination of Triazolam in Human Serum

W. Adams, P. A. Bombardt, U. M. Rykert, 1980 .

Liquid chromatographic determination of guanadrel in laboratory animal diet as the fluorescent acetylacetone derivative

W. Adams, P. A. Bombardt, 1982 .

Predicting Oral Absorption of Drugs: A Case Study with a Novel Class of Antimicrobial Agents

Joe Palandra, P. S. Burton, J. Palandra, 2003, Pharmaceutical Research.

PPARγ-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development.

J. Colca, W. Adams, S. Larsen, 2018, Bioorganic & medicinal chemistry.

Pharmacokinetics and systemic bioavailability of menogaril, an anthracycline antitumor agent, in the mouse, dog, and monkey.

J. E. Brewer, E. Dalm, W. Adams, 1989, Cancer research.

810. Modified steroid hormones. Part V. 6-Methylandrostane derivatives

W. Adams, B. Ellis, V. Petrow, 1957 .

Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.

J. Brieland, Ji-Young Kim, M. Huband, 2007, Journal of medicinal chemistry.

864. 4 : 4-Dimethylsteroids. Part II. Some androstane and pregnane derivatives

W. Adams, D. Patel, V. Petrow, 1956 .

634. Some 4-(dialkylaminoalkylamino)-3-phenylquinolines

W. Adams, D. Hey, 1950 .

Hematologic effects of a novel hemoglobin-based oxygen carrier in normal male and female subjects.

G. S. Hughes, E. Antal, W. Adams, 1995, The Journal of laboratory and clinical medicine.

Quantitative determination of itazigrel in rodent diet by reversed-phase HPLC and evaluation of its stability at 20°C

W. Adams, P. A. Bombardt, B. Bothwell, 1989 .

Absorption of triazolam from pelleted drug-diet mixtures by the mouse: quantitation of alpha-hydroxytriazolam in urine.

W. Adams, P. A. Bombardt, R. Code, 1983, Journal of pharmaceutical sciences.

Phase I study of intravenous menogaril administered intermittently.

J. E. Brewer, J. Abrams, C. Sessa, 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Studies on the metabolism and chiral inversion of ibuprofen in isolated rat hepatocytes.

T. Baillie, S. M. Sanins, W. Adams, 1990, Drug metabolism and disposition: the biological fate of chemicals.

A phase I clinical and pharmacokinetic study of the oral and the oral/ intravenous administration of menogaril

J. E. Brewer, G. Weiss, W. Adams, 1993, Investigational New Drugs.

Synthesis and Bioactivity of Novel Bis(heteroaryl)piperazine (BHAP) Reverse Transcriptase Inhibitors: Structure-Activity Relationships and Increased Metabolic Stability of Novel Substituted Pyridine Analogues.

C. Biles, F. Reusser, I. Althaus, 1997 .