R. Tillyer

发表

Practical asymmetric synthesis of Efavirenz (DMP 266), an HIV-1 reverse transcriptase inhibitor

James R. Moore, L. Tan, A. Choudhury, 1998 .

Synthesis of substituted imidazoles via organocatalysis.

E. Grabowski, R. Tillyer, D. Frantz, 2004, Organic letters.

Highly efficient synthesis of beta-amino acid derivatives via asymmetric hydrogenation of unprotected enamines.

Shane W. Krska, E. Njolito, F. Wang, 2004, Journal of the American Chemical Society.

The importance of synthetic chemistry in the pharmaceutical industry

P. Coleman, J. Alvarez, M. Truppo, 2019, Science.

Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives.

E. Njolito, D. Tellers, J. Armstrong, 2004, Journal of the American Chemical Society.

Practical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate.

L. Tan, E. Grabowski, Cheng-yi Chen, 2005, The Journal of organic chemistry.

Practical enantioselective synthesis of a COX-2 specific inhibitor

L. Tan, P. Reider, E. Grabowski, 2002 .

Reaction d'addition enantioselective efficace a reactif de type complexe organate-zinc

L. Tan, Cheng-yi Chen, R. Tillyer, 1998 .

Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

P. Reider, R. Tillyer, D. Tschaen, 1995 .

Efficient Synthesis of α-Chloro Ketones via Reaction of Organometallic Reagents with N-Methoxy-N-Methylchloroacetamide

R. Tillyer, L. Frey, D. Tschaen, 1996 .

Selective monolithiation of 2,5-dibromopyridine with butyllithium

P. Reider, E. Grabowski, R. Tillyer, 2000 .

Enantioselective syntheses of bicyclo[3.1.0]hexane carboxylic acid derivatives by intramolecular cyclopropanation

L. Tan, R. Volante, R. Tillyer, 2004 .

Practical routes toward the synthesis of 2-halo- and 2-alkylamino-4-pyridinecarboxaldehydes

P. Reider, E. Grabowski, R. Tillyer, 2001 .

Highly Regioselective Synthesis of 1-Aryl-3,4,5-Substituted Pyrazoles

F. Gosselin, E. Grabowski, R. Tillyer, 2006 .

Practical Asymmetric Synthesis of an Endothelin Receptor Antagonist

Paul N. Devine, R. Volante, P. Reider, 1999 .

Synthesis of alpha-amido ketones via organic catalysis: thiazolium-catalyzed cross-coupling of aldehydes with acylimines.

P. Reider, E. Grabowski, R. Tillyer, 2001, Journal of the American Chemical Society.

A Novel, Highly Enantioselective Ketone Alkynylation Reaction Mediated by Chiral Zinc Aminoalkoxides.

L. Tan, P. Reider, E. Grabowski, 1999, Angewandte Chemie.

ChemInform Abstract: Synthesis of α-Amido Ketones via Organic Catalysis: Thiazolium-Catalyzed Cross-Coupling of Aldehydes with Acylimines.

P. Reider, E. Grabowski, R. Tillyer, 2010 .

Stereoselective formation of carbon-carbon bonds via SN2-displacement: synthesis of substituted cycloalkyl[b]indoles.

E. Grabowski, R. Tillyer, Dalian Zhao, 2005, The Journal of organic chemistry.

An efficient enzyme-catalyzed kinetic resolution: large-scale preparation of an enantiomerically pure indole-ethyl ester derivative, a key component for the synthesis of a prostaglandin D2 receptor antagonist, an anti-allergic rhinitis drug candidate

R. Volante, E. Corley, E. Grabowski, 2005 .

Asymmetric synthesis of a prostaglandin D2 receptor antagonist.

E. Grabowski, R. Tillyer, K. Campos, 2005, The Journal of organic chemistry.

13-Asymmetric induction in the aldol reactions of α-methylene-β-alkoxy aldehydes

I. Paterson, R. Tillyer, S. Bower, 1993 .

Stereoselective Conjugate Addition Reactions of α,β-Unsaturated tert-Butyl Esters with Aryllithium Reagents†

A. Caillé, P. Reider, E. Grabowski, 1998 .

High π-face selectivity in anti aldol reactions of E-enol borinates from chiral alkoxymethyl ketones : stereocontrolled synthesis of a C24-C32 polyol subunit of rapamycin

I. Paterson, R. Tillyer, 1993 .

Nucleophilic displacement at benzhydryl centers: asymmetric synthesis of 1,1-diarylalkyl derivatives.

F. Gosselin, D. Mathre, Cheng-yi Chen, 2004, Organic letters.

A Novel, Highly Enantioselective Ketone Alkynylation Reaction Mediated by Chiral Zinc Aminoalkoxides.

L. Tan, P. Reider, E. Grabowski, 1999, Angewandte Chemie.

Efficient syntheses of 2-(3′,5′-difluorophenyl)-3-(4′-methylsulfonylphenyl)cyclopent-2-enone, a potent COX-2 inhibitor

P. Prasit, P. Reider, E. Grabowski, 1999 .

Enantioselective 1,4-addition of aryllithium reagents to α,β-unsaturated tert-butyl esters in the presence of chiral additives

P. Reider, E. Grabowski, R. Tillyer, 1998 .

A general synthesis of substituted indoles from cyclic enol ethers and enol lactones.

R. Tillyer, K. Campos, Kevin R Campos, 2004, Organic letters.

Highly Regioselective Synthesis of 1-Aryl-3,4,5-Substituted Pyrazoles.

F. Gosselin, E. Grabowski, R. Tillyer, 2007 .

Studies in biomimetic polyether synthesis: Construction of an ABCD-ring subunit of etheromycin using polyepoxide cascade cyclisations.

J. Smaill, I. Paterson, R. Tillyer, 1993 .

Highly asymmetric dihydroxylation of 1-aryl-1′-pyridyl alkenes

Matthew L. Maddess, M. Zak, P. Reider, 2000 .

Studies in biomimetic polyether synthesis: Synthesis of an A-ring subunit of etheromycin

I. Paterson, R. Tillyer, G. R. Ryan, 1993 .

Studies in polypropionate synthesis: high π-face selectivity in syn aldol reactions of tin(II) enolates from (R)- and (S)-1-benzyloxy-2-methylpentan-3-one.

I. Paterson, R. Tillyer, 1992 .

Highly Enantioselective 1,2-Addition of Lithium Acetylide-Ephedrate Complexes: Spectroscopic Evidence for Reaction Proceeding via a 2:2 Tetramer, and X-ray Characterization of Related Complexes

J. Cummins, J. Huffman, P. Reider, 2000 .

Dilithium (trimethylstannyl)(2-thienyl)(cyano)cuprate, a synthetically useful higher-order cuprate reagent

R. Tillyer, E. Piers, 1988 .

Pd(0)-catalyzed addition of Me3SnSnMe3 to α,β-alkynic aldehydes and ketones. Synthesis of (Z)-β-trimethylstannyl α,β-alkenic aldehydes and ketones. Preparation and synthetic uses of substituted (Z)-4-trimethylstannyl-1,3-butadienes

R. Tillyer, E. Piers, 1996 .

Concise, stereoselective preparation and synthetic uses of (Z)-4(trimethylstannyl)buta-1,3-dienes

R. Tillyer, E. Piers, 1989 .

Practical asymmetric synthesis of a potent Cathepsin K inhibitor. Efficient palladium removal following Suzuki coupling.

P. Prasit, R. Oballa, E. Grabowski, 2003, The Journal of organic chemistry.

Practical asymmetric synthesis of a selective endothelin A receptor (ETA) antagonist.

H. Satō, T. Nemoto, R. Volante, 2001, Organic Letters.

Asymmetric Reduction of Keto Oxime Ethers Using Oxazaborolidine Reagents. The Enantioselective Synthesis of Cyclic Amino Alcohols.

P. Reider, R. Tillyer, D. Tschaen, 1995 .

Rapid Assembly of Substituted Dihydrocyclohepta[3,4]pyrrolo[1,2-a]indoles via a Novel, Carbene-Based, Rearrangement Reaction

P. Reider, R. Tillyer, L. Frey, 2000 .

Rapid Assembly of Substituted Dihydrocyclohepta[3,4]pyrrolo[1,2-a]indoles via a Novel, Carbene-Based, Rearrangement Reaction.

P. Reider, E. Grabowski, R. Tillyer, 2000 .

An efficient asymmetric synthesis of an estrogen receptor modulator by sulfoxide-directed borane reduction.

D. Zewge, D. Mathre, R. Volante, 2004, Proceedings of the National Academy of Sciences of the United States of America.