C. Musiu

发表

Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.

Silvio Massa, Rino Ragno, Gianluca Sbardella, 2004, Journal of medicinal chemistry.

Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.

Catherine Caillet, S. Cappelle, M. Liuzzi, 2014, Bioorganic & medicinal chemistry letters.

Arylketotetramethylene Analogues of Disoxaril with Anti-Human Rhinovirus 14 Activity

A. Mai, M. Artico, G. Sbardella, 1997 .

Peptide T-araC conjugates: solid-phase synthesis and biological activity of N4-(acylpeptidyl)-araC.

S. Manfredini, M. Marongiu, P. Colla, 2000, Bioorganic & medicinal chemistry.

2-Triazenopyrroles: synthesis and biological activity

A. M. Almerico, A. Lauria, P. Diana, 1999 .

Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

E Novellino, A Lavecchia, E. Novellino, 2001, Journal of medicinal chemistry.

Indolo[3,2-c]cinnolines with antiproliferative, antifungal, and antibacterial activity.

A. Lauria, P. Diana, P. la Colla, 1999, Bioorganic & medicinal chemistry.

Synthesis and antimicrobial activity of new 3-(1-R-3(5)-methyl-4-nitroso-1H-5(3)-pyrazolyl)-5-methylisoxazoles.

A. Bacchi, A. Pani, M. Marongiu, 2000, Bioorganic & medicinal chemistry.

Baricitinib restrains the immune dysregulation in patients with severe COVID-19

O. Olivieri, P. Pelicci, M. Iezzi, 2020 .

Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.

Catherine Caillet, M. Liuzzi, C. Musiu, 2015, Bioorganic & medicinal chemistry letters.

Glycosidopyrroles. Part 2. Acyclic derivatives: 1-(1,3-dihydroxy-2-propoxy)methylpyrroles as potential antiviral agents.

G. Perra, P. Diana, M. Marongiu, 1997, Il Farmaco.

Antimicrobial and antineoplastic activities of new 4-diazopyrazole derivatives

G. Perra, M. Marongiu, C. Musiu, 1998 .

Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.

Catherine Caillet, R. Storer, M. Liuzzi, 2011, Journal of medicinal chemistry.

Glycosidopyrroles. Part 3. Effect of the benzocondensation on acyclic derivatives: 1-(2-hydroxyethoxy) methylindoles as potential antiviral agents.

G. Perra, P. Diana, M. Marongiu, 1998, Farmaco.

Nitroquinolones with broad-spectrum antimycobacterial activity in vitro.

A. Mai, M. Artico, G. Sbardella, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of a Series of Substituted Pyrazolo[3,4‐d]‐1,2,3‐triazoles and Pyrazolo[3,4‐d]oxazoles

G. Perra, S. Manfredini, M. Marongiu, 1998, Archiv der Pharmazie.

2′-C-Methyl Branched Pyrimidine Ribonucleoside Analogues: Potent Inhibitors of RNA Virus Replication

M. Tausek, S. Bergelson, V. Bichko, 2007, Antiviral chemistry & chemotherapy.

Synthesis and antiproliferative activity of 2-triazenothiophenes.

A. Lauria, P. Diana, P. la Colla, 1999, Anticancer research.

3,6-Disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: synthesis and evaluation for antimicrobial and antiviral activity. III.

I. Lampronti, P. la Colla, C. Musiu, 1997, Farmaco.

Antifungal estrogen-like imidazoles. Synthesis and antifungal activities of thienyl and 1H-pyrrolyl derivatives of 1-aryl-2-(1H-imidazol-1-yl)ethane

M. Artico, R. Costi, R. D. Santo, 1997 .

Antifungal Estrogen‐Like Imidazoles. Synthesis and Antifungal Activities of Thienyl and 1H‐Pyrrolyl Derivatives of 1‐Aryl‐2‐(1H‐ imidazol‐1‐yl)ethane.

R. Costi, R. D. Santo, S. Massa, 1997 .

Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity.

A. Lauria, P. Diana, P. la Colla, 1999, Journal of Medicinal Chemistry.

Synthesis and antiviral evaluation of a seven-membered sugar ring nucleoside analog, 9-(5-deoxy-beta-D-allo-septanosyl)-adenine.

R. Storer, M. Liuzzi, J. Sommadossi, 2008, Nucleic acids symposium series.

Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.

R. Storer, M. Liuzzi, J. Sommadossi, 2009, Bioorganic & medicinal chemistry.

Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.

Catherine Caillet, R. Storer, M. Liuzzi, 2016, Journal of medicinal chemistry.

Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.

M. Liuzzi, J. Sommadossi, C. Musiu, 2015, Future medicinal chemistry.

Synthesis, antiviral and antiproliferative activity of a new class of 5-(alkyl or arylthio)-6-vinyl uracils.

G. Spalluto, B. Cacciari, G. Perra, 1996, Anti-cancer drug design.

A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment

S. Ugel, C. Musiu, G. Di Sario, 2021, Cells.

Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis

I. Amit, S. Bicciato, D. Girelli, 2021, medRxiv.

Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer

M. Fassan, D. Tuveson, R. Giugno, 2022, Journal for ImmunoTherapy of Cancer.

Immunization against ROS1 by DNA Electroporation Impairs K-Ras-Driven Lung Adenocarcinomas

M. Papotti, M. Arigoni, L. Conti, 2020, Vaccines.

5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.

A. Mai, G. Maga, M. Artico, 2005, Bioorganic & medicinal chemistry.

Synthesis of tricyclic triazepinones related to nevirapine

S. Castellano, P. Colla, C. Musiu, 2000 .

Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibition.

R. Stroud, D. Santi, S. Ghelli, 1999, Journal of medicinal chemistry.

Baricitinib restrains the immune dysregulation in severe COVID-19 patients.

Antonio Vella, Simone Caligola, Pier Giuseppe Pelicci, 2020, The Journal of clinical investigation.

Baricitinib restrains the immune dysregulation in COVID-19 patients

Antonio Vella, Simone Caligola, Manuela Iezzi, 2020, medRxiv.

Phenotypical Characterization and Isolation of Tumor-Derived Mouse Myeloid-Derived Suppressor Cells.

S. Ugel, V. Bronte, C. Musiu, 2021, Methods in molecular biology.

Synthesis and biological evaluation of [alpha-(1,5-disubstituted 1H-pyrazol-4-yl)benzyl]azoles, analogues of bifonazole.

W. Filippelli, P. la Colla, O. Bruno, 1999, Farmaco.

NITROQUINOLONES WITH BROAD-SPECTRUM ANTIMYCOBACTERIA L

A. Mai, M. Artico, G. Sbardella, 1999 .

Pyrrolo[1,2-f]phenanthridines and related non-rigid analogues as antiviral agents.

A. Lauria, L. Sanna, P. Diana, 2002, European journal of medicinal chemistry.