H. Bohets

发表

In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).

Stephen H Hughes, Peter Williams, Paul J Lewi, 2005, Journal of medicinal chemistry.

Fast monolithic micellar liquid chromatography: an alternative drug permeability assessing method for high-throughput screening.

D. Massart, Y. Vander Heyden, H. Bohets, 2004, Analytical chemistry.

The Novel Azole R126638 Is a Selective Inhibitor of Ergosterol Synthesis in Candida albicans, Trichophyton spp., and Microsporum canis

L. Meerpoel, J. Ausma, F. Odds, 2004, Antimicrobial Agents and Chemotherapy.

Effects of foetal calf serum on cell viability, cytotoxicity and detoxification in the two kidney-derived cell lines LLC-PK1 and MDCK.

M. D. de Broe, H. Bohets, P. Dierickx, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Rapid permeability screening in drug discovery to predict human intestinal absorption.

G. Mannens, H. Bohets, P. Verboven, 2002, Ernst Schering Research Foundation workshop.

Isolation and characterisation of the class alpha, mu and pi glutathione transferases in LLC-PK1 and pig kidney.

M. D. de Broe, H. Bohets, P. Dierickx, 1996, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes.

G. Mannens, J. Leathart, A. Daly, 2002, Biochemical pharmacology.

The cytosolic glutathione S-transferase isoenzymes in the dog kidney cortex as compared with the corresponding MDCK renal cell line.

M. D. de Broe, H. Bohets, P. Dierickx, 1996, Biochimica et biophysica acta.

Characterization of the major cytosolic glutathione transferase in two monkey kidney derived cell lines

H. Bohets, P. Dierickx, 1993, Cell biology international.

Recombinant Escherichia coli cells immobilized in Ca-alginate beads for metabolite production

H. Bohets, J. Simon, A. Durieux, 2009 .

Absence of an active metabolite for the triazole antifungal pramiconazole.

J. Ausma, A. Fothergill, H. Bohets, 2007, Acta Dermato-Venereologica.

Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co‐medication interactions

H. Bohets, P. Verboven, J. Hendrickx, 2000, British journal of pharmacology.

Strategies for absorption screening in drug discovery and development.

G Mannens, P. Annaert, G. Mannens, 2001, Current topics in medicinal chemistry.

The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation

M. D. de Jonge, H. Arkenau, J. D. de Bono, 2015, Clinical Cancer Research.

Correlation between the in vitro cytotoxicity to cultured fathead minnow fish cells and fish lethality data for 50 chemicals

H. Bohets, Paul J. Dierickx, João Brandão, 1992 .

Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells.

H. Bohets, G. V. van Landeghem, P. Dierickx, 1995, Kidney international.

Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor

I. Poggesi, L. Leclercq, F. Cuyckens, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis.

G. Mannens, H. Bohets, A. Shapiro, 2011, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

Correlations between Factors Determining the Pharmacokinetics and Antiviral Activity of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors of the Diaryltriazine and Diarylpyrimidine Classes of Compounds

A. D. Clark, E. Arnold, F. Daeyaert, 2004, Drugs in R&D.

Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans.

A. Paulussen, P. Verhasselt, W. Luyten, 2000, Pharmacogenetics.