J. Girardet

发表

Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase.

M. Allan, Huanming Chen, Weijiang Zhang, 2006, Bioorganic & medicinal chemistry letters.

Novel Nonnucleoside Inhibitors That Select Nucleoside Inhibitor Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase

R. Hamatake, Z. Hong, J. Shim, 2006, Antimicrobial Agents and Chemotherapy.

The involvement of histone H1[0] in chromatin structure.

J. Lawrence, J. Girardet, J. Roche, 1985, Nucleic acids research.

Novel compounds and compositions and methods of use thereof

E. Gunić, J. Girardet, L. Yeh, 2008 .

Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers

Caroline A. Lee, M. Renner, J. Girardet, 2018, Drug Metabolism and Disposition.

Synthesis of 9-(2-β-C-methyl-β-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication

Z. Hong, W. Zhong, Yili Ding, 2005 .

Synthesis and anti-retroviral activity of O,O'-bis(3'-azido-2',3'-dideoxythymidin-5'-yl) phosphoramidate derivatives.

J. Imbach, A. Aubertin, J. Girardet, 1999, Nucleosides & nucleotides.

Chapter Eleven - Urate Crystal Deposition Disease and Gout—New Therapies for an Old Problem

J. Girardet, J. Miner, 2014 .

Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial

Rebecca M. Baker, Phuong Thi Tuyet Nguyen, Carol L. Eyler, 2021, The Lancet Infectious Diseases.

Conformational effects of histones H1 on DNA structure: Comparative study between H1-1, H1o, H5 and sperm holothuira φo

J. Lawrence, J. Girardet, M. Casas, 1988 .

Fluoroaluminate complexes are bifunctional analogues of phosphate in sarcoplasmic reticulum Ca(2+)-ATPase.

J. Girardet, Y. Dupont, A. Troullier, 1992, The Journal of biological chemistry.

Effects of structural defects in sonicated phospholipid vesicles on fusion and ion permeability

M. Kainosho, R. Lawaczeck, J. Girardet, 1975, Nature.

The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir.

J. Imbach, J. Girardet, B. Korba, 1999, Antiviral research.

Characterisation of ATP binding inhibition to the sarcoplasmic reticulum Ca2+‐ATPase by thapsigargin

J. Girardet, Y. Dupont, F. DeJesus, 1993, FEBS letters.

Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.

R. Hamatake, Z. Hong, Suetying Chow, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of new 2'-β-C-methyl related triciribine analogues as anti-HCV agents

S. Lang, Z. Hong, W. Zhong, 2004 .

Conformationally locked nucleosides. Synthesis and hybridization properties of oligodeoxynucleotides containing 2',4'-C-bridged 2'-deoxynucleosides.

E. Gunić, J. Girardet, G. Wang, 1999, Bioorganic & medicinal chemistry letters.

The interpretation of proton magnetic resonance linewidths for lecithin dispersions. Effect of particle size and chain packing.

M. Kainosho, S. Chan, G. Feigenson, 1975, Biochimica et biophysica acta.

A Novel Nonnucleoside Analogue That Inhibits Human Immunodeficiency Virus Type 1 Isolates Resistant to Current Nonnucleoside Reverse Transcriptase Inhibitors

R. Hamatake, Z. Hong, J. Shim, 2006, Antimicrobial Agents and Chemotherapy.

Anti-human immunodeficiency virus type 1 activities of dideoxynucleoside phosphotriester derivatives in primary monocytes/macrophages.

J. Imbach, A. Aubertin, A. Kirn, 1996, Research in virology.

Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate.

J. Imbach, A. Pompon, A. Aubertin, 1995, Journal of medicinal chemistry.

Synthesis, Decomposition Pathways and “In Vitro” Evaluation of Bioreversible Phosphotriesters of Azt

J. Imbach, A. Pompon, A. Aubertin, 1995 .

Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: toward a rational approach for intracellular delivery of nucleoside 5'-monophosphates.

P. la Colla, L. Cappellacci, J. Imbach, 1996, Journal of medicinal chemistry.

Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.

H. Pelicano, J. Imbach, A. Aubertin, 1994, Biochemical pharmacology.

Comparison of Cytotoxicity of Mononucleoside Phosphotriester Derivatives Bearing Biolabile Phosphate Protecting Groups in Normal Human Bone Marrow Progenitor Cells

J. Imbach, J. Sommadossi, A. Aubertin, 1996 .

New insights regarding the potential of the pronucleotide approach in antiviral chemotherapy.

J. Imbach, A. Pompon, J. Girardet, 1996, Acta biochimica Polonica.

Rational design for cytosolic delivery of nucleoside monphosphates : “SATE” and “DTE” as enzyme-labile transient phosphate protecting groups

J. Imbach, J. Girardet, S. Benzaria, 1993 .

Evidence of a calcium-induced structural change in the ATP-binding site of the sarcoplasmic-reticulum Ca2+-ATPase using terbium formycin triphosphate as an analogue of Mg-ATP.

J. Girardet, Y. Dupont, J. Lacapere, 1989, European journal of biochemistry.

Synthesis and cytotoxicity of 4-amino-5-oxopyrido[2,3-d]pyrimidine nucleosides.

E. Gunić, J. Girardet, Z. Pietrzkowski, 2000, Journal of medicinal chemistry.

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Huanming Chen, A. Pinkerton, Samedy Ouk, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis, and antiviral activity of alpha-nucleosides: D- and L-isomers of lyxofuranosyl- and (5-deoxylyxofuranosyl)benzimidazoles.

J. Girardet, M. Migawa, L. Townsend, 1998, Journal of medicinal chemistry.

Design, Synthesis and Antiviral Activity of α-L-Arabinofuranosyl Derivatives of 2-Substituted-5,6-dichlorobenzimidazoles

J. Girardet, L. Townsend, J. Drach, 1998 .

Design, Synthesis, and Antiviral Activity of α‐Nucleosides: D‐ and L‐Isomers of Lyxofuranosyl‐ and (5‐Deoxylyxofuranosyl)benzimidazoles.

John A. Walker, J. Girardet, M. Migawa, 1998 .

Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents.

C. Varaprasad, Z. Hong, W. Zhong, 2007, Bioorganic chemistry.

Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase.

J. Wu, W. Zhong, G. Larson, 2005, Bioorganic & medicinal chemistry letters.

Synthesis of β-l-Lyxofuranosyl Benzimidazoles by an Unexpected Intramolecular Displacement Reaction

J. Girardet, L. Townsend, 1999 .

Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.

J. Wu, N. Yao, G. Larson, 2006, Bioorganic chemistry.

6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate prodrugs as potent hepatitis C virus inhibitors.

R. Hamatake, Z. Hong, F. Rong, 2007, Bioorganic & medicinal chemistry letters.

Conformationally locked nucleosides. Synthesis and stereochemical assignments of 2′-C,4′-C-bridged bicyclonucleosides

E. Gunić, J. Girardet, Guangyi Wang, 1999 .

Design, synthesis, and antiviral activity of adenosine 5'-phosphonate analogues as chain terminators against hepatitis C virus.

J. Wu, Z. Hong, W. Zhong, 2005, Journal of medicinal chemistry.

Comments on nucleotide delivery forms

J. Imbach, J. Girardet, C. Périgaud, 1996 .

Increase of the Anti‐HIV Activity of D4T in Human T‐Cell Culture by the Use of the Sate Pronucleotide Approach

J. Imbach, A. Aubertin, A. Kirn, 1996 .

Fluoride, beryllium and ADP combine as a ternary complex in aqueous solution as revealed by a multinuclear NMR study

J. Issartel, J. Girardet, A. Dupuis, 2004, European Biophysics Journal.

Chapter 2 - Recent developments in the chemistry of nucleosides

S. Lang, J. Girardet, 2007 .

Multinuclear NMR Study of Fluoroaluminate Complexes in Aqueous Solution

J. Girardet, E. J. Martínez, C. Morat, 1996 .

Synthesis and cytotoxicity of 4'-C- and 5'-C-substituted toyocamycins.

E. Gunić, J. Girardet, Z. Pietrzkowski, 2001, Bioorganic & medicinal chemistry.

Synthesis of Nucleoside Libraries on Solid Support. II. 2,6,8‐Trisubstituted Purine Nucleosides Using 8‐Bromoguanosine as Precursor

F. Rong, J. Girardet, Z. Hong, 2004, Nucleosides, nucleotides & nucleic acids.

Synthesis and Anticancer Activity of 4‐Amino‐5‐oxo‐8‐(β‐D‐xylofuranosyl)pyrido[2,3‐d]pyrimidine

J. Girardet, Z. Pietrzkowski, Guangyi Wang, 2001 .

Increase of the anti-HIV activity of D4T in human T-cell culture by the use of the sate pronucleotide approach

J. Imbach, A. Aubertin, A. Kirn, 1995 .

Synthesis of 2'-beta-C-methyl toyocamycin and sangivamycin analogues as potential HCV inhibitors.

Z. Hong, Yili Ding, J. Girardet, 2005, Bioorganic & medicinal chemistry letters.

Design and evaluation of a potential mutagen for Hepatitis C virus.

Z. Hong, J. Shim, J. Girardet, 2007, Bioorganic & medicinal chemistry letters.

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

R. Terkeltaub, D. Hagerty, J. Girardet, 2016, Arthritis Research & Therapy.

Ruthenium II tris (bathophenanthroline disulfonate), a powerful fluorescent stain for detection of proteins in gel with minimal interference in subsequent mass spectrometry analysis

T. Rabilloud, J. Strub, J. Lunardi, 2000 .

Localization of a putative magnesium-binding site within the cytoplasmic domain of the sarcoplasmic reticulum Ca(2+)-ATPase.

I. Bally, J. Girardet, Y. Dupont, 1993, European journal of biochemistry.

Ellipticity changes of the sarcoplasmic reticulum Ca2+‐ATPase induced by cation binding and phosphorylation

J. Girardet, Y. Dupont, 1992, FEBS letters.

Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans

Caroline A. Lee, David M. Wilson, Vishal D. Shah, 2018, Drug Metabolism and Disposition.

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

R. Terkeltaub, D. Hagerty, J. Girardet, 2016, Arthritis Research & Therapy.

The Pronucleotide Approach. III. Synthesis, Anti-HBV Activity and Stability Studies of the Bis(S-pivaloyl-2-thioethyl) Phosphotriester Derivative of Acyclovir

J. Imbach, A. Pompon, J. Girardet, 1997 .

Experimental evidence for asymmetrical shielding of nucleosomal DNA by histones.

J. Lawrence, J. Girardet, 1979, Nucleic acids research.

The role of the central globular domain of histone H5 in chromatin structure.

J. Lawrence, J. Girardet, D. Chan, 1984, Journal of biomolecular structure & dynamics.

Synthesis and Antitumor Properties of Some Neutral Triesters of 5-Fluoro-2′-deoxyuridine-5′-monophosphate and 3′,5′-Cyclic Monophosphate

J. Balzarini, E. Clercq, J. Imbach, 1995 .

NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS

J. Girardet, Z. Hong, Michael B. Landesman, 2004 .

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Huanming Chen, A. Pinkerton, Samedy Ouk, 2011, Bioorganic & medicinal chemistry letters.

NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS

J. Girardet, Z. Hong, Michael B. Landesman, 2004 .

A reexamination of the stopped-flow measured hydrogen-deuterium exchange rates in nucleic acid double helices.

J. Ramstein, J. Girardet, 1992, Biochimica et biophysica acta.

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

R. Terkeltaub, D. Hagerty, J. Girardet, 2016, Arthritis Research & Therapy.