J. Reid

发表

Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses.

G. McGaughey, Youwei Yan, M. Lai, 2008, Journal of medicinal chemistry.

Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.

G. McGaughey, Youwei Yan, M. Lai, 2011, Journal of medicinal chemistry.

Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4*

P. Darke, S. Munshi, D. Hall, 2015, The Journal of Biological Chemistry.

Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase

A. W. Shaw, Mee Ra Heo, I. Raheem, 2021, Nature Communications.

Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequence.

R. Martinus, J. Reid, G. G. Midwinter, 1989, The Journal of biological chemistry.

Structure of Human Prostasin, a Target for the Regulation of Hypertension*

H. Su, P. Darke, S. Munshi, 2008, Journal of Biological Chemistry.

A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein

H. Su, K. Vora, M. Eddins, 2019, Nature Communications.

Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity.

Sujata Sharma, K. Lumb, S. Soisson, 2012, Journal of the American Chemical Society.

Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.

S. Stirdivant, L. Kuo, P. Darke, 2005, Biochemistry.

Expression, purification and crystallization of human prolylcarboxypeptidase.

Sujata Sharma, D. Hall, R. Diehl, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.

S. So, H. Su, A. Brooun, 2020, Protein expression and purification.

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

Sujata Sharma, D. Klein, K. Lumb, 2013, The Journal of Biological Chemistry.

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase.

Sujata Sharma, D. Klein, D. Hall, 2017, Nature chemical biology.

Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics

Eric Langlois, Alexandre Caron, Mihai Petcu, 2012, Science Translational Medicine.

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

Christopher L. Daniels, D. Hazuda, Sujata Sharma, 2010, Journal of Virology.

Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species.

Dawn M. Toolan, G. McGaughey, J. Uslaner, 2018, Bioorganic & medicinal chemistry letters.

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

Sujata Sharma, D. Hall, R. Diehl, 2010, BMC Structural Biology.

Structural characterization of nonactive site, TrkA-selective kinase inhibitors

D. Henze, H. Su, M. Ziebell, 2016, Proceedings of the National Academy of Sciences.

Crystal Structure of the Apo, Unactivated Insulin-like Growth Factor-1 Receptor Kinase

S. Stirdivant, L. Kuo, P. Darke, 2002, The Journal of Biological Chemistry.

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

P. Darke, S. Munshi, D. Hall, 2011, The Journal of Biological Chemistry.

Crystal structures of the N‐terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors

S. Munshi, H. Kotani, M. Ikuta, 2007, Protein science : a publication of the Protein Society.

The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design.

Deping Wang, Sujata Sharma, W. Shipe, 2017, Bioorganic & medicinal chemistry letters.

Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation.

J. Reid, D. Husbands, 1985, The Biochemical journal.