J. Hang

发表

Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.

Taraneh Mirzadegan, Klaus Klumpp, S. Tsing, 2008, Journal of medicinal chemistry.

Wadim L. Matochko, G. A. Lazar, M. Ultsch, 2019 .

Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members

Wadim L. Matochko, G. A. Lazar, M. Ultsch, 2019, mAbs.

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture*

R. Devos, J. Symons, N. Cammack, 2006, Journal of Biological Chemistry.

Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.

Wen Jiang, R. Devos, J. Symons, 2007, Bioorganic & medicinal chemistry letters.

1 Slow-binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus

A. M. Giannetti, S. Harris, S. Pogam, 2009 .

Analysis of the interaction of 16S rRNA and cytoplasmic membrane with the C-terminal part of the Streptococcus pneumoniae Era GTPase.

J. Hang, G. Zhao, T. Meier, 2001, European journal of biochemistry.

Endonuclease and helicase activities of bacteriophage lambda terminase: changing nearby residue 515 restores activity to the gpA K497D mutant enzyme.

Y. Hwang, M. Feiss, J. Hang, 2000, Virology.

Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Y. Li, T. Mirzadegan, N. Cammack, 2007, Biochemical and biophysical research communications.

Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides.

Y. Li, S. Rajendran, N. Cammack, 2004, Biochemical and biophysical research communications.

2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases

J. Deval, N. Cammack, Yu Li, 2009 .

Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase

N. Arora, S. Harris, Mark Smith, 2010 .

Diphenyl Ether Non‐Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties

Y. Li, D. Stefanidis, N. Arora, 2009, ChemMedChem.

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase.

Yu Li, Andrew Briggs, Klaus Klumpp, 2008, Bioorganic & medicinal chemistry letters.

Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors.

S. Rajendran, N. Cammack, H. Overton, 2003, Nucleic acids research.

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

B. Yaspan, J. Hackney, Lawren C. Wu, 2019, Cell.

951 SILIBININ INHIBITS HCV REPLICATION IN VITRO

Amy D. Fung, P. Ferenci, N. Cammack, 2009 .

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Christian A. Siltanen, J. Egen, Yvonne Chinn, 2015, Nature.

The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody.

M. van Lookeren Campagne, A. Estevez, C. Ciferri, 2015, The Biochemical journal.

Characterization of the 16S rRNA- and membrane-binding domains of Streptococcus pneumoniae Era GTPase: structural and functional implications.

Genshi Zhao, J. Hang, 2003, European journal of biochemistry.

Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

April Wong, Klaus Klumpp, Hannah J. Whittington, 2009, The Journal of Biological Chemistry.

ATPase center of bacteriophage lambda terminase involved in post-cleavage stages of DNA packaging: identification of ATP-interactive amino acids.

M. Feiss, J. Hang, B. Tack, 2000, Journal of molecular biology.

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein.

M. Elazar, J. Glenn, E. Sklan, 2011, Virology.

Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.

Xianfeng Lin, Taraneh Mirzadegan, Klaus Klumpp, 2010, Bioorganic & medicinal chemistry letters.

In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor.

R. Ptak, N. Cammack, H. Javanbakht, 2010, Antiviral research.

The functional asymmetry of cosN, the nicking site for bacteriophage lambda DNA packaging, is dependent on the terminase binding site, cosB.

M. Feiss, C. Catalano, J. Hang, 2001, Biochemistry.

Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors.

Amy D. Fung, N. Arora, S. Harris, 2010, Bioorganic & medicinal chemistry letters.

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

B. Yaspan, J. Hackney, Y. Franke, 2020, Cell.

Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.

S. Tsing, T. Mirzadegan, S. Harris, 2008, Journal of medicinal chemistry.