D. Patel

发表

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

S. Hughes, E. Arnold, K. Das, 2012, Retrovirology.

Application of fragment screening by x-ray crystallography for the identification of novel chemical scaffolds targeting viral proteins of hiv and influenza

D. Patel, 2013 .

Fragment screening and HIV therapeutics.

E. Arnold, J. Bauman, D. Patel, 2012, Topics in current chemistry.

Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease

E. Arnold, E. LaVoie, K. Das, 2014, Journal of medicinal chemistry.

Phenyl substituted 3-hydroxypyridin-2(1H)-ones: inhibitors of influenza A endonuclease.

E. Arnold, E. LaVoie, K. Das, 2013, Bioorganic & medicinal chemistry.

3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.

E. Arnold, E. LaVoie, K. Das, 2013, ACS medicinal chemistry letters.

Differential isotopic enrichment to facilitate characterization of asymmetric multimeric proteins using hydrogen/deuterium exchange mass spectrometry.

S. Tuske, E. Arnold, P. Griffin, 2015, Analytical chemistry.

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

R. Hochstrasser, E. Arnold, K. Das, 2013, Nature chemistry.

Dissecting Human and Influenza Virus Interaction with qFRET Technology

Liu, D. Patel, Chuchu Liu, 2022 .

Mechanism of the Hsp90 chaperone cycle : investigation of divalent ion binding and conformational change

D. Patel, 2012 .

NMR studies of DNA (R+)n.(Y-)n.(Y+)n triple helices in solution: imino and amino proton markers of T.A.T and C.G.C+ base-triple formation.

D. Patel, M. Rosen, C. R. de los Santos, 1989, Biochemistry.

Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening.

Eddy Arnold, Sameer Ahmed, A. Shatkin, 2013, Journal of medicinal chemistry.

Effect of tetramethylammonium ion on the helix-to-coil transition of poly(deoxyadenylylthymidine): a nuclear magnetic resonance and calorimetric investigation.

K. Breslauer, L. Marky, D. Patel, 1981, Biochemistry.

Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.

G. Margison, P. Potter, P. Georgiadis, 1989, Nucleic acids research.

Multifaceted Roles of Crystallography in Modern Drug Discovery

E. Arnold, G. Scapin, D. Patel, 2015, NATO Science for Peace and Security Series A: Chemistry and Biology.

Advantages of crystallographic fragment screening: functional and mechanistic insights from a powerful platform for efficient drug discovery.

Eddy Arnold, E. Arnold, J. Bauman, 2014, Progress in biophysics and molecular biology.

Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors.

Steven F. Baker, E. Arnold, E. LaVoie, 2013, ACS chemical biology.

Comparative modeling of methylentetrahydrofolate reductase (MTHFR) enzyme and its mutational assessment: in silico approach

M. Yadav, A. Nayarisseri, D. Patel, 2010 .

Identification of Alternative Binding Sites for Inhibitors of HIV-1 Ribonuclease H Through Comparative Analysis of Virtual Enrichment Studies

Anthony K. Felts, Krystal LaBarge, Joseph D. Bauman, 2011, J. Chem. Inf. Model..

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain*

A. Engelman, Erik Serrao, R. Levy, 2016, The Journal of Biological Chemistry.

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

S. Hughes, E. Arnold, K. Das, 2012, Retrovirology.

Adventures in Small Molecule Fragment Screening by X-ray Crystallography

Joseph D. Bauman, Disha Patel, Eddy Arnold, 2015 .

Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening.

A. Shatkin, E. Arnold, K. Das, 2013, Journal of medicinal chemistry.