D. Deschěnes

发表

Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.

Sébastien Gagné, Eric Langlois, Jean-François Truchon, 2014, Bioorganic & medicinal chemistry letters.

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.

Chun Xing Li, R. Young, S. Charleson, 2005, Bioorganic & medicinal chemistry letters.

Nitric oxide attachment to SPIONs: Demonstration of the covalent S NO bond in a nanodelivery system

E. Sacher, L. Yahia, S. Laurent, 2020 .

Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy.

R. Oballa, R. Gordon, J. Guay, 2011, Bioorganic & medicinal chemistry letters.

The discovery and synthesis of highly potent subtype selective phosphodiesterase 4D inhibitors.

R. Young, D. Nicholson, Y. Girard, 2010, Bioorganic & medicinal chemistry letters.

Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitors.

R. Young, J. Mancini, D. Nicholson, 2009, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of 8-biarylquinolines: a novel class of PDE4 inhibitors.

R. Young, J. Mancini, H. Perrier, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis, and supramolecular properties of bis-crown ether modified peptides

N. Voyer, D. Deschěnes, J. Roby, 1995 .

Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).

J. Falgueyret, R. Oballa, J. Guay, 2010, Bioorganic & medicinal chemistry letters.

The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14.

J. Gauthier, S. Kargman, J. Mancini, 2011, Bioorganic & medicinal chemistry letters.

Enantiospecific synthesis via sequential diastereofacial and diastereotopic group selective reactions : enantiodivergent synthesis of syn-1,3-polyols

Zhaoyin Wang, D. Deschěnes, 1992 .

2-heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors.

D. Riendeau, C. Brideau, C. Chan, 1999, Bioorganic & medicinal chemistry letters.

Enantiospecific Synthesis via Sequential Diastereofacial and Diastereotopic Group Selective Reactions: Enantiodivergent Synthesis of syn-1,3-Polyols.

Zhaoyin Wang, D. Deschěnes, 2010 .

Geometrical recognition ability of flexible bis-crown ether peptidic receptors

N. Voyer, D. Deschěnes, J. Roby, 1992 .

Process Development and Large-Scale Synthesis of a PDE4 Inhibitor

D. Deschěnes, D. Macdonald, R. Helmy, 2006 .

2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.

R Gordon, R Fortin, D. Riendeau, 1998, Bioorganic & medicinal chemistry letters.

Identification of a potent and selective non-basic cathepsin K inhibitor.

J. Falgueyret, M. Mcgrath, M. Percival, 2006, Bioorganic & medicinal chemistry letters.

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K.

J. Falgueyret, M. Percival, R. Young, 2005, Bioorganic & Medicinal Chemistry Letters.

Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptor.

P. Clark, Steve Rowland, D. Denis, 2008, Bioorganic & medicinal chemistry letters.

Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitors.

S. Charleson, J. Mancini, H. Perrier, 2006, Bioorganic & medicinal chemistry letters.

Heteroleptic ruthenium bis-terpyridine complexes bearing a 4-(dimethylamino)phenyl donor and free coordination sites for hydrogen photo-evolution.

G. Hanan, D. Deschěnes, Thomas Auvray, 2019, Dalton transactions.

The chemo- and enantioselective cyclopropanation of polyenes: chiral auxiliary vs chiral reagent-based approach

D. Deschěnes, H. Juteau, A. Charette, 1996 .