M. Mkrtichyan

发表

Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed

J. Janik, S. Khleif, R. Abu Eid, 2016, Cancer Immunology Research.

Selective Inhibition of Regulatory T Cells by Targeting the PI3K–Akt Pathway

J. Berzofsky, L. Ozbun, S. Khleif, 2014, Cancer Immunology Research.

MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects

Shannon K. Boi, J. Banchereau, S. Barry, 2020, Nature Immunology.

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8+ T-cell proliferation and survival

J. Janik, S. Khleif, R. Abu Eid, 2015, Oncoimmunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts

Amanda R. Campbell, F. Lund-Johansen, Yair Benita, 2016 .

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

S. Khleif, R. Abu Eid, M. Mkrtichyan, 2013, Journal of Immunotherapy for Cancer.

Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma.

Victor V Lobanenkov, D. Cribbs, D. Loukinov, 2011, Cellular immunology.

Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathology.

D. Cribbs, T. Ross, I. Petrushina, 2010, Human gene therapy.

Expression Level on T Cell Subsets Novel Mechanism Dependent on PD-1 B7-DC-Ig Enhances Vaccine Effect by a

Y. Najjar, L. Ozbun, Geoffrey C. Guittard, 2012 .

Anti‐PD‐1 synergizes with cyclophosphamide to induce potent anti‐tumor vaccine effects through novel mechanisms

Y. Najjar, S. Khleif, M. Mkrtichyan, 2011, European journal of immunology.

Enhanced Therapeutic Efficacy and Memory of Tumor-Specific CD8 T Cells by Ex Vivo PI3K-δ Inhibition.

J. Janik, E. Celis, S. Khleif, 2017, Cancer research.

Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-Testis Antigen, Brother of the Regulator of Imprinted Sites1

Victor V Lobanenkov, D. Loukinov, D. Cribbs, 2007, The Journal of Immunology.

Imprinted Sites Antigen, Brother of the Regulator of Immunization with the Novel Cancer-Testis Histologically Unrelated Tumors by Elicitation of T Cell Responses to

Victor V Lobanenkov, D. Loukinov, D. Cribbs, 2006 .

Antitumor efficacy of DNA vaccination to the epigenetically acting tumor promoting transcription factor BORIS and CD80 molecular adjuvant

Victor V Lobanenkov, D. Loukinov, D. Cribbs, 2006, Journal of cellular biochemistry.

Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy

S. Khleif, G. S. E. Razavi, M. Mkrtichyan, 2017, Journal of Immunotherapy for Cancer.

Reducing AD-Like Pathology in 3xTg-AD Mouse Model by DNA Epitope Vaccine — A Novel Immunotherapeutic Strategy

E. Head, D. Cribbs, I. Petrushina, 2008, PloS one.

Antigen-Specific Antitumor Responses Induced by OX40 Agonist Are Enhanced by the IDO Inhibitor Indoximod

J. Janik, S. Hammond, S. Khleif, 2018, Cancer Immunology Research.

Antigen-Speci fi c Antitumor Responses Induced by OX 40 Agonist Are Enhanced by the IDO Inhibitor

J. Janik, S. Hammond, S. Khleif, 2018 .

Differential PI3Kδ Signaling in CD4+ T-cell Subsets Enables Selective Targeting of T Regulatory Cells to Enhance Cancer Immunotherapy.

S. Khleif, M. Mkrtichyan, P. Rodriguez, 2017, Cancer research.

Immunostimulant adjuvant patch enhances humoral and cellular immune responses to DNA immunization.

D. Cribbs, G. Glenn, T. Ross, 2008, DNA and cell biology.

DNA, but not protein vaccine based on mutated BORIS antigen significantly inhibits tumor growth and prolongs the survival of mice

Victor V Lobanenkov, D. Loukinov, D. Cribbs, 2008, Gene Therapy.

Kδ signaling in CD 4 + T cell subsets enables selective targeting of T regulatory cells to enhance cancer immunotherapy

S. Khleif, M. Mkrtichyan, P. Rodriguez, 2016 .

Prototype Alzheimer's disease epitope vaccine induced strong Th2-type anti-Abeta antibody response with Alum to Quil A adjuvant switch.

D. Cribbs, I. Petrushina, A. Ghochikyan, 2006, Vaccine.

SANTAVACTM: Summary of Research and Development

P. Lokhov, M. Mkrtichyan, E. Balashova, 2019, Vaccines.

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

N. Hacohen, R. Sullivan, K. Flaherty, 2019, Nature Immunology.

Programmed death-1 & its ligands: promising targets for cancer immunotherapy.

J. Janik, S. Khleif, M. Mkrtichyan, 2015, Immunotherapy.

Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells

J. Berzofsky, T. Whiteside, N. Tarasova, 2016, Cancer Immunology Research.

Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer

S. Steinberg, J. Berzofsky, O. Rahma, 2014, Journal of Translational Medicine.

B7-DC-Ig Enhances Vaccine Effect by a Novel Mechanism Dependent on PD-1 Expression Level on T Cell Subsets

Y. Najjar, L. Ozbun, Geoffrey C. Guittard, 2012, The Journal of Immunology.

Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer

S. Steinberg, J. Berzofsky, O. Rahma, 2014, Journal of Translational Medicine.

Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

V. Vasilevko, D. Cribbs, I. Petrushina, 2008, Journal of Neuroinflammation.

DNA prime–protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice

D. Cribbs, I. Petrushina, A. Ghochikyan, 2010, Gene Therapy.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Prototype Alzheimer’s Disease Vaccine Using the Immunodominant B Cell Epitope from β-Amyloid and Promiscuous T Cell Epitope Pan HLA DR-Binding Peptide1

V. Vasilevko, D. Cribbs, I. Petrushina, 2005, The Journal of Immunology.

Single variable domains from the T cell receptor β chain function as mono- and bifunctional CARs and TCRs

A. Kamb, M. Mkrtichyan, D. Warshaviak, 2019, Scientific Reports.

Anti-Aβ1–11 Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers*

A. Kiyatkin, C. Glabe, D. Cribbs, 2007, Journal of Biological Chemistry.

DNA epitope vaccine containing complement component C3d enhances anti-amyloid-β antibody production and polarizes the immune response towards a Th2 phenotype

D. Cribbs, T. Ross, I. Petrushina, 2008, Journal of Neuroimmunology.

Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis

H. Robins, C. Sanders, J. Janik, 2017, Cancer Immunology Research.

MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects

Shannon K. Boi, J. Banchereau, S. Barry, 2020, Nature Immunology.

IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status

R. Nandre, S. Khleif, M. Mkrtichyan, 2022, Cancer immunology research.

Pan HLA DR-Binding Peptide -Amyloid and Promiscuous T Cell Epitope b the Immunodominant B Cell Epitope from Prototype Alzheimer's Disease Vaccine Using

V. Vasilevko, D. Cribbs, I. Petrushina, 2005 .

Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.

A. Kiyatkin, C. Glabe, D. Cribbs, 2007, The Journal of biological chemistry.

A Therapeutic Vaccine Targeting Rat BORIS (CTCFL) for the Treatment of Rat Breast Cancer Tumors

D. Loukinov, A. Anderson, Victor Lobanenkov, 2023, International journal of molecular sciences.