S. Engle

发表

Integrating human pluripotent stem cells into drug development.

Sandra J. Engle, S. Engle, D. Puppala, 2013, Cell stem cell.

Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis.

P S Gartside, G. Boivin, T. Doetschman, 1999, Cancer research.

Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons

R. Kleiman, S. Engle, Laura Blaha, 2018, Neuron.

Impaired Cardiac Contractility in Mice Lacking Both the AE3 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{Cl}^{-}{/}\mathrm{HCO}_{3}^{-}\) \end{document} Exchanger and the NKCC1 N

T. Doetschman, M. Ashraf, Yigang Wang, 2008, Journal of Biological Chemistry.

Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

N. Horseman, E. Montecino-Rodriguez, K. Dorshkind, 1997, The EMBO journal.

Fibroblast growth factor-2 mediates pressure-induced hypertrophic response.

S. Pawlowski, T. Doetschman, J. Lorenz, 1999, The Journal of clinical investigation.

Other transgenic mutation assays: APRT: A versatile in vivo resident reporter of local mutation and loss of heterozygosity

J. Tischfield, P. Stambrook, S. Engle, 1996, Environmental and molecular mutagenesis.

Characterizing the composition of iPSC derived cells from bulk transcriptomics data with CellMap

Kejie Li, Xinmin Zhang, Baohong Zhang, 2022, Scientific Reports.

Engineering multicellular living systems—a Keystone Symposia report

Melissa L. Kemp, Alex J. Hughes, P. Arlotta, 2022, Annals of the New York Academy of Sciences.

Generation of mice with a conditional allele for transforming growth factor beta 1 gene

S. Pawlowski, M. Yin, G. Boivin, 2009, Genesis.

Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice.

G. Boivin, T. Doetschman, G. Babcock, 2004, Cellular immunology.

Pharmacokinetics of Oral d-Serine in d-Amino Acid Oxidase Knockout Mice

N. Brandon, A. Sawa, T. Tsukamoto, 2012, Drug Metabolism and Disposition.

Human inducible pluripotent stem cells: Realization of initial promise in drug discovery.

R. Kleiman, S. Engle, 2021, Cell stem cell.

The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells

Zhao-Wen Wang, Xue-Jun Li, Ping Liu, 2015, Scientific Reports.

Small Molecule Screening in Human Induced Pluripotent Stem Cell-derived Terminal Cell Types*

S. Engle, Sandra J Engle, Fabien Vincent, 2013, The Journal of Biological Chemistry.

Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue.

B. Fermini, M. Pletcher, B. Anson, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Investigation of SAMD1 ablation in mice

Robert Liefke, S. Engle, T. Ozolins, 2023, Scientific Reports.

Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice.

S. Pawlowski, G. Boivin, T. Doetschman, 2002, Cancer research.

The Logic of Signaling from the Cell Surface to the Nucleus

Nelson D. Horseman, Sandra J. Engle, Anca Ralescu, 1997, Trends in Endocrinology & Metabolism.

Altered Hematopoiesis, Behavior, and Sexual Function in μ Opioid Receptor–deficient Mice

H. Jansen, M. Lehman, J. Tischfield, 1997, The Journal of experimental medicine.

d‐amino acid oxidase knockout (Dao −/−) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption

Paul J. Harrison, D. Bannerman, N. Brandon, 2015, The European journal of neuroscience.

Genetically engineered mouse models in drug discovery research.

J. Stock, J. Mcneish, S. Engle, 2010, Methods in molecular biology.

Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao −/−) mice

Paul J. Harrison, D. Bannerman, N. Brandon, 2016, The European journal of neuroscience.

Self-antigen recognition by TGFβ1-deficient T cells causes their activation and systemic inflammation

G. Boivin, T. Doetschman, G. Babcock, 2006, Laboratory Investigation.

Characterization of human-induced pluripotent stem cell-derived cardiomyocytes: bioenergetics and utilization in safety screening.

Yvonne Will, Payal Rana, Y. Will, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Advances in Brief Elimination of Colon Cancer in Germ-free Transforming Growth Factor Beta 1-deficient Mice 1

S. Pawlowski, G. Boivin, T. Doetschman, 2002 .

Increased burst‐firing of ventral tegmental area dopaminergic neurons in d‐amino acid oxidase knockout mice in vivo

Paul J. Harrison, N. Brandon, J. Schweimer, 2014, The European journal of neuroscience.

Human Pluripotent Stem Cell–Derived Kidney Model for Nephrotoxicity Studies

A. D. Rodrigues, P. Bajaj, C. Steppan, 2018, Drug Metabolism and Disposition.

Engineeringmulticellular living systems—aKeystone Symposia report

Melissa L. Kemp, Alex J. Hughes, P. Arlotta, 2022 .

Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.

H. Simmonds, G. Boivin, J. Tischfield, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Generation of mice with a conditional allele for the transforming growth factor beta3 gene

S. Pawlowski, M. Yin, G. Boivin, 2009, Genesis.

Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

A. Sigova, R. Fremeau, D. Bumcrot, 2023, bioRxiv.

Pharmacokinetics of Oral d-Serine in d-Amino Acid Oxidase Knockout Mice

N. Brandon, A. Sawa, T. Tsukamoto, 2012, Drug Metabolism And Disposition.

Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

A. Sigova, R. Fremeau, D. Bumcrot, 2024, Scientific reports.