S. Hauschka

发表

Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

R. David Hawkins, John K. Hall, R. D. Hawkins, 2017, Nature Communications.

Translation of Cardiac Myosin Activation With 2-Deoxy-ATP to Treat Heart Failure Via an Experimental Ribonucleotide Reductase-Based Gene Therapy

G. Mahairas, M. Regnier, J. Chamberlain, 2016, JACC. Basic to translational science.

Expression of a transfected mouse muscle-creatine kinase gene is induced upon growth factor deprivation of myogenic but not of nonmyogenic cells.

J. Johnson, J. B. Jaynes, S. Hauschka, 1989, Developmental biology.

Development of Novel Micro-dystrophins with Enhanced Functionality

James M. Allen, J. Chamberlain, K. Hollinger, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Analysis of muscle creatine kinase regulatory elements in recombinant adenoviral vectors.

J. Chamberlain, D. Hartigan-O’Connor, C. Kirk, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene

S. Hauschka, S. Hauschka, J. Buskin, 1989, Molecular and cellular biology.

E-box sites and a proximal regulatory region of the muscle creatine kinase gene differentially regulate expression in diverse skeletal muscles and cardiac muscle of transgenic mice

H. Haugen, C. Clegg, S. Hauschka, 1996, Molecular and cellular biology.

expression in Duchenne muscular dystrophy dogs Hematopoietic stem cell transplantation does not restore dystrophin

S. Tapscott, R. Storb, J. Kornegay, 2013 .

The mouse muscle creatine kinase cDNA and deduced amino acid sequences: Comparison to evolutionarily related enzymes

J. B. Jaynes, J. Chamberlain, S. Hauschka, 2005, Journal of Molecular Evolution.

Myocyte-mediated arginase expression controls hyperargininemia but not hyperammonemia in arginase-deficient mice.

W. Grody, S. Cederbaum, Chuhong Hu, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Regulation of creatine kinase induction in differentiating mouse myoblasts

J. B. Jaynes, J. Chamberlain, S. Hauschka, 1985, Molecular and cellular biology.

mouse muscle creatine kinase gene. binds to the muscle-specific enhancer of the Identification of a myocyte nuclear factor that

S. Hauschka, J. Buskin, 2013 .

Heart and bone tumors in transgenic mice.

R. Palmiter, R. Brinster, J. Peschon, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Myocardin. a novel potentiator of SRF-mediated transcription in cardiac muscle.

S. Hauschka, 2001, Molecular cell.

Improvement in survival and muscle function in an mdx/utrn −/− double mutant mouse using a human retinal dystrophin transgene

Robert A. H. White, M. Bilgen, D. Pinson, 2006, Neuromuscular Disorders.

Muscle creatine kinase sequence elements regulating skeletal and cardiac muscle expression in transgenic mice

B. Wold, J. Johnson, S. Hauschka, 1989, Molecular and cellular biology.

Regulation of creatine kinase induction in differentiating mouse myoblasts

J. B. Jaynes, J. Chamberlain, S. Hauschka, 1985, Molecular and Cellular Biology.

Peptide antibody specific for the amino terminus of skeletal muscle alpha-actin.

Santhosh K. P. Kumar, K. Titani, S. Hauschka, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Peptide antibody specific for the amino terminus of skeletal muscle a-actin ( muscle development / human myoblasts / actin isozymes / HPLC )

K. Titani, S. Hauschka, J. Bulinski, 2022 .

Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle

S. Amacher, S. Hauschka, S. Hauschka, 1993, Molecular and cellular biology.

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer

J. Johnson, J. B. Jaynes, S. Hauschka, 1988, Molecular and cellular biology.

A Novel Cytoplasmic Dual Specificity Protein Tyrosine Phosphatase Implicated in Muscle and Neuronal Differentiation (*)

E. Krebs, J. Dixon, M. Wenderoth, 1996, The Journal of Biological Chemistry.

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

R. Friedline, W. Philbrick, You-Ree Cho, 2009, Diabetes.

Improved adenoviral vectors for gene therapy of Duchenne muscular dystrophy

J. Chamberlain, A. Amalfitano, S. Hauschka, 1997, Neuromuscular Disorders.

Stable transduction of myogenic cells with lentiviral vectors expressing a minidystrophin

J. Chamberlain, M. Reyes, S. Hauschka, 2005, Gene Therapy.

Viral vectors for gene transfer of micro-, mini-, or full-length dystrophin

S. Harper, J. Chamberlain, C. Dellorusso, 2002, Neuromuscular Disorders.

Muscle Gene E-box Control Elements

S. Hauschka, S. Apone, 1995, The Journal of Biological Chemistry.

EVIDENCE FOR QUANTITATIVELY DIFFERENT TRANSCRIPTIONAL ACTIVITIES AND THE BINDING OF DISTINCT REGULATORY FACTORS

S. Hauschka, S. Apone, 1995 .

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy

Hui Li, Samadrita Bhattacharyya, Florian Schmidt, 2017, Science Translational Medicine.

p53-dependent activation of the mouse MCK gene promoter: identification of a novel p53-responsive sequence and evidence for cooperation between distinct p53 binding sites.

M. Reed, A. Braithwaite, P. Jackson, 1995, Gene expression.

Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy

T. Conlon, B. Byrne, M. Styner, 2023, Science Translational Medicine.

Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate

John K. Hall, M. Regnier, J. Chamberlain, 2019, JACC. Basic to translational science.

In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy

C. Gersbach, A. Asokan, S. Hauschka, 2020, Molecular therapy. Methods & clinical development.

Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts

J. Johnson, J. B. Jaynes, J. Chamberlain, 1986, Molecular and cellular biology.

Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice

H. Haugen, C. Clegg, D. Donoviel, 1996, Molecular and cellular biology.

Increased glycogen accumulation in transgenic mice overexpressing glycogen synthase in skeletal muscle.

P. Roach, J. Lawrence, J. Manchester, 1996, Proceedings of the National Academy of Sciences of the United States of America.

AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility.

G. Mahairas, M. Regnier, C. Murry, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Li, S, Kimura, E, Fall, BM, Reyes, M, Angello, JC, Welikson, R et al.. Stable transduction of myogenic cells with lentiviral vectors expressing a minidystrophin. Gene Ther 12: 1099-1108

J. Chamberlain, M. Reyes, S. Hauschka, 2005 .

Cell based dATP delivery as a therapy for chronic heart failure

R. Tian, D. Raftery, C. Murry, 2023, bioRxiv.

A Novel Site in the Muscle Creatine Kinase Enhancer Is Required for Expression in Skeletal but Not Cardiac Muscle (*)

S. Hauschka, Christine Fabre-Suver, 1996, The Journal of Biological Chemistry.

Ex vivo gene transfer using adenovirus-mediated full-length dystrophin delivery to dystrophic muscles

S. Kochanek, J. Yang, J. Huard, 1998, Gene Therapy.

Transcriptional Regulation oftheMuscleCreatine Kinase Geneand Regulated Expression inTransfected MouseMyoblasts

J. B. Jaynes, Jane E. Johnson, S. Hauschka, 1986 .

Split intein-mediated protein trans-splicing to express large dystrophins.

S. Hauschka, James M. Allen, Dirk Grimm, 2024, Nature.

Corrigendum: Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

John K. Hall, R. D. Hawkins, J. Chamberlain, 2017, Nature Communications.

M-creatine kinase gene expression in mechanically overloaded skeletal muscle of transgenic mice.

S. Hauschka, R. Tsika, Liying Gao, 1995, The American journal of physiology.