W. Whish

发表

Novel inhibitors of poly(ADP-ribose) synthetase.

M. R. Purnell, W. Whish, 1980, The Biochemical journal.

The modification of nuclear proteins by ADP-ribosylation.

D. Rickwood, W. Whish, A. Macgillivray, 1977, European journal of biochemistry.

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

M. Threadgill, W. Whish, C. Y. Watson, 1998, Bioorganic & medicinal chemistry.

2-nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the PARP inhibitor 5-bromoisoquinolinone.

D. Naughton, M. Threadgill, W. Whish, 1999, Bioorganic & medicinal chemistry letters.

5-Nitrofuran-2-ylmethyl group as a potential bioreductively activatedpro-drug system

M. Threadgill, W. Whish, C. Y. Watson, 1997 .

Poly(ADP‐ribose) glycohydrolase in mouse fibroblast cells (LS cells)

S. Shall, W. Whish, P. Stone, 1973, FEBS letters.

ADP-ribosylation of nuclear proteins.

M. R. Purnell, W. Whish, P. Stone, 1980, Biochemical Society transactions.

Synthesis of thiophenecarboxamides, thieno[3,4-c]pyridin-4(5H)-ones and thieno[3,4-d]pyrimidin-4(3H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

M. Threadgill, W. Whish, A. Shinkwin, 1999, Bioorganic & medicinal chemistry.

The distribution of calmodulin/calmodulin binding proteins in the rat tapeworm, Hymenolepis diminuta.

C. Branford-White, W. Whish, J. Eastlake, 1994, Comparative biochemistry and physiology. Biochemistry and molecular biology.

Acyl derivatives of alpha-chymotrypsin.

T. Viswanatha, W. Whish, R. Oliver, 1967, Biochemical and biophysical research communications.

The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.

A. Lehmann, S. Shall, W. Whish, 1974, Experimental cell research.

Stimulation of poly(ADP-ribose) polymerase activity by the anti-tumour antibiotic, streptozotocin.

M. I. Davies, S. Shall, W. Whish, 1975, Biochemical and biophysical research communications.

The effects of benzamide ADP-ribosyl transferase inhibitors on cell survival and DNA strand-break repair in irradiated mammalian cells.

P. D. Lewis, J. Lunec, W. Whish, 1986, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Post-irradiation sensitization with the ADP-ribosyltransferase inhibitor 3-acetamidobenzamide.

J. Lunec, W. Whish, W. Cramp, 1984, The British journal of cancer. Supplement.

Effect of polyamines and Mg++ on poly(ADP-ribose) synthesis and ADP-ribosylation of histones in wheat.

W. Whish, P. Stone, A. Whitby, 1979, Biochemical and biophysical research communications.

Tumour necrosis factor α stimulated rheumatoid synovial microvascular endothelial cells exhibit increased shear rate dependent leucocyte adhesion in vitro

S. Abbot, W. Whish, C. Stevens, 1999, Annals of the rheumatic diseases.

Poly(adenosine diphosphate ribose) polymerase in Physarum polycephalum.

S. Shall, W. Whish, M. Brightwell, 1971, The Biochemical journal.

Post-irradiation inhibition of scheduled DNA synthesis and stimulation of ADP-ribosylation in sensitive and resistant L5178Y murine lymphoma cells.

J. Lunec, W. Whish, W. Cramp, 1983, International journal of radiation biology and related studies in physics, chemistry, and medicine.

In vitro poly-(ADP-ribosyl)ation of chromatin proteins in the rat tapeworm, Hymenolepis diminuta.

R. Apweiler, W. Whish, S. Kappus, 1993, Comparative biochemistry and physiology. B, Comparative biochemistry.

Identification of ADPR-transferase activity in the rat tapeworm, Hymenolepis diminuta.

R. Apweiler, W. Whish, R. V. Brunt, 1990, Comparative biochemistry and physiology. B, Comparative biochemistry.

A model for the initial phase of cell/surface interactions based on ligand binding phenomena.

R. Eisenthal, W. Whish, J. Hubble, 1995, The Biochemical journal.

Poly(adenosine diphosphoribose) polymerase activity and adenosine diphosphate ribosylation of proteins during pancreatic degeneration and regeneration.

G. Poirier, W. Whish, A. Lord, 1981, Cancer research.

A method for analyzing the ADP-ribosylation of nuclear proteins on polyacrylamide gels.

M. R. Purnell, W. Whish, P. Stone, 1981, Analytical biochemistry.

The immobilization of adenine nucleotides on polysaccharides by using glutaraldehyde coupling and borohydride reduction.

P. Gacesa, W. Whish, 1978, Biochemical Journal.

Poly(Adenosine Diphosphate Ribose) in Physarum polycephalum

S. Shall, W. Whish, P. Stone, 1973 .

The effect of phenones on poly(adenosine diphosphate ribose) synthetase from porcine thymus [proceedings].

M. R. Purnell, W. Whish, 1980, Biochemical Society transactions.