S. Bhat

发表

Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic.

Martin Brassard, D. Veber, S. Beauchemin, 2011, Journal of medicinal chemistry.

UDP-Gal: GlcNAc-R β1,4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme

I. Brockhausen, S. Bhat, John G. Riley, 2006, Glycoconjugate Journal.

XPB, a subunit of TFIIH, is a target of the natural product triptolide.

Jun O. Liu, A. Demain, Yongjun Dang, 2011, Nature chemical biology.

Effect of nitroxoline on angiogenesis and growth of human bladder cancer.

Jun O. Liu, J. Xu, M. Pomper, 2010, Journal of the National Cancer Institute.

Structure‐activity relationship study of itraconazole, a broad‐range inhibitor of picornavirus replication that targets oxysterol‐binding protein (OSBP)

Jun O. Liu, A. Brancale, F. V. van Kuppeveld, 2018, Antiviral research.

Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole.

Jun O. Liu, W. Shi, S. Bhat, 2010, ACS medicinal chemistry letters.

Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1.

Jun O. Liu, L. Amzel, Renxiao Wang, 2013, Bioorganic & medicinal chemistry.

Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.

Michelle S. Miller, Jun O. Liu, L. Amzel, 2013, Journal of medicinal chemistry.

Tricyclic thiazoles are a new class of angiogenesis inhibitors.

Jun O. Liu, J. Shim, S. Bhat, 2013, Bioorganic & medicinal chemistry letters.

A simple and efficient route to the FKBP-binding domain from rapamycin.

Jun O. Liu, S. Bhat, Wei Li, 2011, Tetrahedron letters.

Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis.

Jun O. Liu, W. Bishai, C. Chong, 2011, Tuberculosis.

Inhibition of Amyloid A Amyloidogenesis in Vivo and in Tissue Culture by 4-Deoxy Analogues of Peracetylated 2-Acetamido-2-Deoxy-α- and β-d-Glucose

S. Bhat, W. Szarek, E. Elimova, 2004 .

Inhibition of amyloid A amyloidogenesis in vivo and in tissue culture by 4-deoxy analogues of peracetylated 2-acetamido-2-deoxy-alpha- and beta-d-glucose: implications for the treatment of various amyloidoses.

S. Bhat, W. Szarek, E. Elimova, 2004, The American journal of pathology.

Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action.

Sean D. Taverna, Yingming Zhao, P. Cole, 2018, Journal of the American Chemical Society.

Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase.

Jun O. Liu, E. Novotná, M. Krátký, 2012, Tuberculosis.

Targeting of phosphonoacetate to the liver: Synthesis of a phosphonoacetate-trilactoside conjugate

S. Bhat, W. Szarek, A. Vaino, 2000 .

Novel glycosaminoglycan precursors as anti-amyloid agents, Part III

Zhanjiang Li, S. Bhat, W. Szarek, 2002, Journal of Molecular Neuroscience.

It takes two binding sites for calcineurin and NFAT to tango.

Jun O. Liu, J. Xu, S. Bhat, 2009, Molecular cell.

Inhibition of Eukaryotic Translation Elongation by Cycloheximide and Lactimidomycin

Tilman Schneider-Poetsch, Ben Shen, Rachel Green, 2010, Nature chemical biology.

Inhibition of angiogenesis by the antifungal drug itraconazole.

Jun O. Liu, C. Chong, D. Sullivan, 2007, ACS chemical biology.

Reaction of Azides with Tetrathiomolybdate: Reduction and Imine Formation

S. Chandrasekaran, S. Bhat, A. Ramesha, 1995 .

Sodium Perborate/Acetic Anhydride: A Convenient Reagent for the Conversion of Cyclic Acetals to Esters

S. Chandrasekaran, S. Bhat, A. Ramesha, 1995 .

A highly selective methodology for the direct conversion of acetals to esters

S. Chandrasekaran, S. Bhat, N. Chidambaram, 1992 .

Reaction of Azides with Tetrathiomolybdate: Reduction and Imine Formation.

S. Chandrasekaran, S. Bhat, A. Ramesha, 2010 .

ISOMERIZATION OF LONGIFOLENE TO ISOLONGIFOLENE CATALYZED BY MONTMORILLONITE CLAY

K. R. Prabhu, S. Bhat, A. Ramesha, 1999 .

DiazoReagentswithSmallStericFootprintsforSimultaneousArming/ SARStudiesofAlcohol-ContainingNaturalProductsviaOHInsertion

Jun O. Liu, Yongjun Dang, D. Romo, 2011 .

Efficient parallel synthesis of macrocyclic peptidomimetics.

Daniel Fortin, Martin Brassard, Ruoxi Lan, 2008, Bioorganic & medicinal chemistry letters.

Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo.

Jun O. Liu, T. Shapiro, Nirbhay Kumar, 2009, Chemistry & biology.

Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets.

Jun O. Liu, W. Bishai, G. Lamichhane, 2010, Chemistry & biology.

Substituted oxines inhibit endothelial cell proliferation and angiogenesis.

Jun O. Liu, C. Chong, J. Shim, 2012, Organic & biomolecular chemistry.

Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion.

Jun O. Liu, Yongjun Dang, D. Romo, 2011, ACS chemical biology.

The HBV drug entecavir - effects on HIV-1 replication and resistance.

Lin Shen, Yan Zhou, Jun O. Liu, 2007, The New England journal of medicine.

Rapamycin-inspired macrocycles with new target specificity

Jun O. Liu, G. Fischer, C. Tse, 2018, Nature Chemistry.

Short-Chain Aliphatic Polysulfonates Inhibit the Entry of Plasmodium into Red Blood Cells

I. Crandall, K. Kain, S. Bhat, 2002, Antimicrobial Agents and Chemotherapy.

Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases.

Jun O. Liu, W. Shi, Ying Zhang, 2012, Bioorganic & medicinal chemistry.

Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B.

Jun O. Liu, R. Green, John C Jewett, 2011, RNA.

Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2.

J. Stivers, A. Majumdar, S. Bhat, 2019, DNA repair.

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

R. Siliciano, J. Margolick, T. Quinn, 2011, Journal of Virology.

Oxygenation of alkenes with t-BuOOH catalysed by β-cyclodextrin borate

S. Chandrasekaran, S. Bhat, 1996 .

Oxygenation of Alkenes with t‐BuOOH Catalyzed by β‐Cyclodextrin Borate.

S. Chandrasekaran, S. Bhat, 1996 .

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

Jun O. Liu, R. Siliciano, J. Margolick, 2011, The Journal of antimicrobial chemotherapy.

Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies

M. Sung, Kevin W. Huynh, J. Stivers, 2023, bioRxiv.

Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding

J. Stivers, MD ABU HASAN HOWLADER, M. Bianchet, 2023, ACS chemical biology.

Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity.

Jun O. Liu, Yongjun Dang, D. Romo, 2007, Chemistry & biology.

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

R. Siliciano, J. Margolick, T. Quinn, 2011, Journal of Virology.

Tricyclic thiazoles are a new class of angiogenesis inhibitors.

Jun O. Liu, J. Shim, S. Bhat, 2013, Bioorganic & Medicinal Chemistry Letters.

The HBV drug entecavir - effects on HIV-1 replication and resistance.

Jun O. Liu, R. Siliciano, C. Chong, 2007, The New England journal of medicine.

Antiviral Research

A. Brancale, K. Pasunooti, S. Bhat, 2023 .