E. Niederberger

发表

Computational functional genomics based analysis of pain-relevant micro-RNAs

A. Ultsch, J. Lötsch, E. Niederberger, 2015, Human Genetics.

The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model.

M. Meissner, G. Geisslinger, E. Niederberger, 2016, Biochemical pharmacology.

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

Doris Marko, Ralph Hoessel, Gerhard Eisenbrand, 1999, Nature Cell Biology.

Inhibitor kappa B kinase beta dependent cytokine upregulation in nociceptive neurons contributes to nociceptive hypersensitivity after sciatic nerve injury.

G. Geisslinger, E. Niederberger, A. Häussler, 2012, The journal of pain : official journal of the American Pain Society.

Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice

G. Geisslinger, E. Niederberger, S. C. Fleck, 2019, Neuropharmacology.

Lack of effect of a P2Y6 receptor antagonist on neuropathic pain behavior in mice

G. Geisslinger, E. Niederberger, A. Schmidtko, 2014, Pharmacology Biochemistry and Behavior.

The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors

A. Minden, G. Geisslinger, E. Niederberger, 2012, Behavioural Brain Research.

NADPH Oxidase-4 Maintains Neuropathic Pain after Peripheral Nerve Injury

A. Shah, R. Brandes, D. Del Turco, 2012, The Journal of Neuroscience.

The Impact of Diet and Exercise on Drug Responses

M. Parnham, E. Niederberger, 2021, International journal of molecular sciences.

The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats

J. Lötsch, G. Geisslinger, E. Niederberger, 2002, Neuroscience Letters.

The Role of AlphαSynuclein in Mouse Models of Acute, Inflammatory and Neuropathic Pain

E. Niederberger, C. Möser, Moritz Möller, 2022, Cells.

The Protein Kinase IKKε Is a Potential Target for the Treatment of Inflammatory Hyperalgesia

N. Ferreirós, G. Geisslinger, E. Niederberger, 2011, The Journal of Immunology.

HyperalgesiaTarget for the Treatment of Inflammatory Is a Potential e The Protein Kinase IKK

N. Ferreirós, G. Geisslinger, E. Niederberger, 2011 .

The IKK‐NF‐κB pathway: a source for novel molecular drug targets in pain therapy?

G. Geisslinger, E. Niederberger, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased CNS uptake and enhanced antinociception of morphine‐6‐glucuronide in rats after inhibition of P‐glycoprotein

J. Lötsch, G. Geisslinger, E. Niederberger, 2002, Journal of neurochemistry.

A rapid screening method for a single nucleotide polymorphism (SNP) in the human MOR gene.

J. Lötsch, S. Grösch, G. Geisslinger, 2001, British journal of clinical pharmacology.

The non-canonical IκB kinases IKKε and TBK1 as potential targets for the development of novel therapeutic drugs.

G. Geisslinger, E. Niederberger, C. Möser, 2013, Current molecular medicine.

Impaired acute and inflammatory nociception in mice lacking the p50 subunit of NF-kappaB.

G. Geisslinger, E. Niederberger, A. Schmidtko, 2007, European journal of pharmacology.

Opposite effects of rofecoxib on NF- κ B and AP-1 activation 1

S. Grösch, E. Niederberger, I. Tegeder, 2002 .

Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen.

S. Grösch, G. Geisslinger, K. Brune, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Erythropoietin and G-csf Receptors in Human Tumor Cells: Expression and Aspects regarding Functionality

J. Debus, Christoph Blum, T. Knoch, 2002, Tumori.

The glutamate transporter GLAST is involved in spinal nociceptive processing.

G. Geisslinger, E. Niederberger, A. Schmidtko, 2006, Biochemical and biophysical research communications.

Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxib.

G. Geisslinger, E. Niederberger, Christine Manderscheid, 2006, Biochemical and biophysical research communications.

Comparative proteomic analysis of the rat spinal cord in inflammatory and neuropathic pain models

M. Karas, A. Pfenninger, G. Geisslinger, 2005, Neuroscience Letters.

4 Ds in health research—working together toward rapid precision medicine

M. Parnham, Jochen Maas, G. Geisslinger, 2019, EMBO molecular medicine.

AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids

N. Ferreirós, G. Geisslinger, E. Niederberger, 2017, Neuropharmacology.

G protein-independent G1 cell cycle block and apoptosis with morphine in adenocarcinoma cells: involvement of p53 phosphorylation.

S. Grösch, K. Scholich, G. Geisslinger, 2003, Cancer research.

The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception.

H. Korf, G. Geisslinger, E. Niederberger, 2007, Biochemical and biophysical research communications.

Opposite Effects of Rofecoxib on Nuclear Factor-κB and Activating Protein-1 Activation

S. Grösch, G. Geisslinger, E. Niederberger, 2003, Journal of Pharmacology and Experimental Therapeutics.

Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice

R. Gurke, E. Niederberger, Y. Schreiber, 2022, International journal of molecular sciences.

AMP-activated kinase and the endogenous endocannabinoid system might contribute to antinociceptive effects of prolonged moderate caloric restriction in mice

N. Ferreirós, G. Geisslinger, E. Niederberger, 2017, Molecular pain.

Age-Dependent Changes in the Inflammatory Nociceptive Behavior of Mice

G. Geisslinger, E. Niederberger, M. Wolters, 2015, International journal of molecular sciences.

Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord

P. Ruth, T. Deller, G. Geisslinger, 2005, Pain.

Computational functional genomics based analysis of pain-relevant micro-RNAs

A. Ultsch, J. Lötsch, E. Niederberger, 2015, Human Genetics.

Lycobetaine acts as a selective topoisomerase IIβ poison and inhibits the growth of human tumour cells

D. Marko, G. Eisenbrand, F. Boege, 2001, British Journal of Cancer.

COX‐2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX‐2 inhibitor celecoxib

S. Grösch, G. Geisslinger, E. Niederberger, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MicroRNAs as new players in the pain game

J. Lötsch, G. Geisslinger, E. Niederberger, 2011, PAIN®.

Modulation of central nervous system–specific microRNA-124a alters the inflammatory response in the formalin test in mice

G. Geisslinger, E. Niederberger, O. Q. Russe, 2013, PAIN®.

The impact of endurance exercise on global and AMPK gene-specific DNA methylation.

Claudia Knothe, E. Resch, G. Geisslinger, 2016, Biochemical and biophysical research communications.

The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways

M. Meissner, E. Niederberger, S. Schiffmann, 2020, International journal of molecular sciences.

Specific Inhibition of IκB Kinase Reduces Hyperalgesia in Inflammatory and Neuropathic Pain Models in Rats

Gerd Geisslinger, Martin Michaelis, M. Michaelis, 2004, The Journal of Neuroscience.

Celecoxib loses its anti‐inflammatory efficacy at high doses through activation of NF‐κB

S. Grösch, G. Geisslinger, E. Niederberger, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Proteomics and NF-κB: an update

G. Geisslinger, E. Niederberger, 2013, Expert review of proteomics.

Novel findings in pain processing pathways: implications for miRNAs as future therapeutic targets

G. Geisslinger, E. Niederberger, O. Q. Russe, 2013, Expert review of neurotherapeutics.

Activation of the AMP-activated protein kinase reduces inflammatory nociception.

G. Geisslinger, E. Niederberger, O. Q. Russe, 2013, The journal of pain : official journal of the American Pain Society.

Update on the pathobiology of neuropathic pain

G. Geisslinger, E. Niederberger, Hilmar Kühlein, 2008, Expert review of proteomics.

LPS inhibits caspase 3-dependent apoptosis in RAW264.7 macrophages induced by the AMPK activator AICAR.

S. Grösch, G. Geisslinger, E. Niederberger, 2014, Biochemical and biophysical research communications.

Inhibition of HDAC Enzymes Contributes to Differential Expression of Pro-Inflammatory Proteins in the TLR-4 Signaling Cascade

G. Geisslinger, E. Niederberger, Moritz Möller, 2020, International journal of molecular sciences.

Drugging the pain epigenome

E. Resch, M. Parnham, G. Geisslinger, 2017, Nature Reviews Neurology.

Activation of c‐Jun‐N‐terminal‐kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers

S. Grösch, G. Geisslinger, E. Niederberger, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis.

N. Ferreirós, B. Brüne, M. Grez, 2014, Biochemical pharmacology.

Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53.

S. Grösch, G. Geisslinger, E. Niederberger, 2005, Biochemical pharmacology.

Analysis of NF-κB signaling pathways by proteomic approaches

G. Geisslinger, E. Niederberger, 2010, Expert review of proteomics.

Effects of selective COX‐1 and ‐2 inhibition on formalin‐evoked nociceptive behaviour and prostaglandin E2 release in the spinal cord

G. Geisslinger, E. Niederberger, I. Tegeder, 2001, Journal of neurochemistry.

The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia

A. Pfenninger, G. Geisslinger, E. Niederberger, 2004, Pain.

Cofilin phosphorylation is involved in nitric oxide/cGMP-mediated nociception.

C. Brenneis, E. Niederberger, C. Möser, 2009, Biochemical and biophysical research communications.

TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes

G. Geisslinger, E. Niederberger, O. Q. Russe, 2015, Journal of Neuroinflammation.

TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes

G. Geisslinger, E. Niederberger, O. Q. Russe, 2015, Journal of Neuroinflammation.

Modulation of spinal nociceptive processing through the glutamate transporter GLT-1

J. Rothstein, G. Geisslinger, E. Niederberger, 2002, Neuroscience.

Cleavage of SNAP‐25 ameliorates cancer pain in a mouse model of melanoma

G. Geisslinger, E. Niederberger, A. Schmidtko, 2017, European journal of pain.

The effects of COX-2 selective and non-selective NSAIDs on the initiation and progression of atherosclerosis in ApoE−/− mice

R. Busse, B. Fisslthaler, I. Fleming, 2007, Journal of Molecular Medicine.

Nerve Injury Evoked Loss of Latexin Expression in Spinal Cord Neurons Contributes to the Development of Neuropathic Pain

M. Karas, R. Marschalek, G. Geisslinger, 2011, PloS one.

Comparative Proteomic Analysis as a Method to Investigate Inflammatory and Neuropathic Pain

E. Niederberger, 2011 .

Proteomics in Neuropathic Pain Research

Gerd Geisslinger, G. Geisslinger, E. Niederberger, 2008, Anesthesiology.

Activation of AMPK and its Impact on Exercise Capacity

G. Geisslinger, E. Niederberger, O. Q. Russe, 2015, Sports Medicine.

Effects of the selective COX-2 inhibitors celecoxib and rofecoxib on human vascular cells.

S. Grösch, G. Geisslinger, E. Niederberger, 2004, Biochemical pharmacology.

Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine

C. Freitag, S. Toennes, E. Niederberger, 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats

P. Ruth, G. Geisslinger, E. Niederberger, 2002, Neuroscience Letters.

Investigational drugs targeting the prostaglandin E2 signaling pathway for the treatment of inflammatory pain

S. Grösch, G. Geisslinger, E. Niederberger, 2017, Expert opinion on investigational drugs.

Inhibition of NF‐ κ B and AP‐1 activation by R‐ and S‐flurbiprofen 1 2

S. Grösch, G. Geisslinger, K. Brune, 2001 .

Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers

N. Ferreirós, G. Geisslinger, E. Niederberger, 2020, Cells.

Cysteine-Rich Protein 2, a Novel Downstream Effector of cGMP/cGMP-Dependent Protein Kinase I-Mediated Persistent Inflammatory Pain

F. Hofmann, P. Ruth, H. Allescher, 2008, The Journal of Neuroscience.

Maillard reaction products modulating the growth of human tumor cells in vitro.

D. Marko, T. Hofmann, O. Frank, 2003, Chemical research in toxicology.

Inhibition of NF‐KB and AP‐1 activation by R‐ and S‐flurbiprofen 1, 2

S. Grösch, G. Geisslinger, K. Brune, 2001 .

Inhibition of NF − κ B and AP-1 activation by Rand S-flurbiprofen

S. Grösch, G. Geisslinger, K. Brune, 2000 .

cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I

J. Schlossmann, P. Ruth, R. Motterlini, 2008, The Journal of Neuroscience.

AMP-activated protein kinase is activated by non-steroidal anti-inflammatory drugs.

Claudia Knothe, N. Ferreirós, G. Geisslinger, 2015, European journal of pharmacology.

Rab27a Contributes to the Processing of Inflammatory Pain in Mice

T. Tolmachova, M. Seabra, G. Geisslinger, 2020, Cells.

Novel Insights into Molecular Mechanisms of Chronic Pain

E. Niederberger, 2020, Cells.

AGMO Inhibitor Reduces 3T3-L1 Adipogenesis

E. Werner, H. Stark, K. Watschinger, 2021, Cells.

5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift

K. Scholich, G. Geisslinger, E. Niederberger, 2019, International journal of molecular sciences.

Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen.

S. Grösch, G. Geisslinger, K. Brune, 2001, The FASEB Journal.

The IKK‐NF‐κB pathway: a source for novel molecular drug targets in pain therapy?

G. Geisslinger, E. Niederberger, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Update on the pathobiology of neuropathic pain

G. Geisslinger, E. Niederberger, Hilmar Kühlein, 2008, Expert review of proteomics.

The IKK-NF- (cid:1) B pathway: a source for novel molecular drug targets in pain therapy?

E. Niederberger, Gerd Geisslinger, 2008 .

Distinct molecular mechanisms contribute to the reduction of melanoma growth and tumor pain after systemic and local depletion of alpha‐Synuclein in mice

E. Niederberger, Moritz Möller, A. Wilken-Schmitz, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Opposite Effects of Rofecoxib on Nuclear Factor- (cid:1) B and Activating Protein-1 Activation

S. Grösch, G. Geisslinger, E. Niederberger, 2003 .

p 53 Phosphorylation with Morphine in Adenocarcinoma Cells : Involvement of Cell Cycle Block and Apoptosis 1 G Protein-independent G Updated

S. Grösch, K. Scholich, G. Geisslinger, 2003 .