Raphael Ceccaldi

发表

Repair Pathway Choices and Consequences at the Double-Strand Break.

A. D’Andrea, Raphael Ceccaldi, B. Rondinelli, 2016, Trends in cell biology.

Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.

J. Soulier, M. Cavazzana‐Calvo, A. D’Andrea, 2012, Cell stem cell.

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions.

F. Sigaux, J. Soulier, A. Baruchel, 2011, Blood.

Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.

G. Adelmant, J. Marto, A. D’Andrea, 2014, Molecular cell.

Biallelic inactivation of REV7 is associated with Fanconi anemia.

J. Soulier, A. Baruchel, D. Bluteau, 2016, The Journal of clinical investigation.

Gene polymorphisms and cytokine plasma levels as predictive factors of complications after cardiopulmonary bypass.

L. Trinquart, E. Tartour, P. Menasché, 2012, Journal of Thoracic and Cardiovascular Surgery.

CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.

A. D’Andrea, M. Altmeyer, Raphael Ceccaldi, 2018, Molecular cell.

e- Blood Myelodysplasia and leukemia of Fanconi anemia are associated with a speciﬁc pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions

F. Sigaux, J. Soulier, A. Baruchel, 2011 .

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.

A. D’Andrea, D. Kozono, Raphael Ceccaldi, 2016, Cell reports.

The Fanconi anaemia pathway: new players and new functions

A. D’Andrea, Raphael Ceccaldi, P. Sarangi, 2016, Nature Reviews Molecular Cell Biology.

Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer.

G. Shapiro, A. D’Andrea, P. Konstantinopoulos, 2015, Cancer discovery.

A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors

J. Tainer, G. Shapiro, A. D’Andrea, 2021, Nature Cancer.

Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair

Stephen J. Elledge, S. Elledge, A. D’Andrea, 2015, Nature.

EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation

A. D’Andrea, J. Jonkers, E. Gogola, 2017, Nature Cell Biology.

Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients.

J. Soulier, Q. Waisfisz, D. Stoppa-Lyonnet, 2011, The Journal of clinical investigation.

A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance.

A. D’Andrea, K. Mouw, U. Matulonis, 2015, Cancer research.

Amendment history : Corrigendum ( March 2017 ) Biallelic inactivation of REV 7 is associated with Fanconi anemia

J. Soulier, A. Baruchel, D. Bluteau, 2019 .

Nuclear NAD+ homeostasis is essential for naive and chemoresistant BRCA1/2-deficient tumor survival

D. Musiani, E. Marangoni, Raphael Ceccaldi, 2021, bioRxiv.

Polymerase Theta Inhibition Kills Homologous Recombination Deficient Tumors

J. Tainer, G. Shapiro, A. D’Andrea, 2020, bioRxiv.

A Prospective Study of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Type 1 Gaucher Disease Patients

R. Porcher, V. Vanneaux, J. Larghero, 2013, PloS one.

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells

J. Soulier, Nadia Vasquez, C. Lachaud, 2023, Nucleic acids research.

Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis

S. Zinn-Justin, D. Loew, F. Dingli, 2023, Nature.