E. Lafer

发表

Structure-function analysis of the auxilin J-domain reveals an extended Hsc70 interaction interface.

Y. Ishikawa-Brush, P. Hart, Alexander B. Taylor, 2003, Biochemistry.

Structural basis of J cochaperone binding and regulation of Hsp70.

A. Hinck, Alexander B. Taylor, R. Sousa, 2007, Molecular cell.

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

Gregory F Weber, L. Bonewald, Jean X. Jiang, 2012, Proceedings of the National Academy of Sciences.

A parametrically constrained optimization method for fitting sedimentation velocity experiments.

Gary Gorbet, Borries Demeler, Emre H Brookes, 2014, Biophysical journal.

Structure of the Hsp110:Hsc70 nucleotide exchange machine.

Borries Demeler, Jorge Cuellar, Oscar Llorca, 2008, Molecular cell.

Eps15 Homology Domain-NPF Motif Interactions Regulate Clathrin Coat Assembly during Synaptic Vesicle Recycling*

George J Augustine, Jennifer R Morgan, G. Augustine, 2003, Journal of Biological Chemistry.

Polyglutamyl derivatives of tetrahydrofolate as substrates for Lactobacillus casei thymidylate synthase.

J. Montgomery, E. Lafer, R. Kisliuk, 1981, Biochemistry.

AP180 and AP-2 Interact Directly in a Complex That Cooperatively Assembles Clathrin*

L. Zheng, Weihua Hao, K. Prasad, 1999, The Journal of Biological Chemistry.

Probing the phosphoinositide binding site of the clathrin assembly protein AP-2 with photoaffinity labels.

G. Prestwich, J. Chen, K. Prasad, 1998, Archives of biochemistry and biophysics.

Regulation of AP-3 Function by Inositides

G. Prestwich, J. Chen, J. Falck, 1997, The Journal of Biological Chemistry.

Inhibition of Clathrin Assembly by High Affinity Binding of Specific Inositol Polyphosphates to the Synapse-specific Clathrin Assembly Protein AP-3 (*)

M. Bembenek, E. Lafer, S. Shears, 1995, The Journal of Biological Chemistry.

Developmental Regulation of the Direct Interaction between the Intracellular Loop of Connexin 45.6 and the C Terminus of Major Intrinsic Protein (Aquaporin-0)*

Jean X. Jiang, E. Lafer, X. Yin, 2005, Journal of Biological Chemistry.

Antibodies against Z DNA react with the macronucleus but not the micronucleus of the hypotrichous ciliate stylonychia mytilus

Alfred Nordheim, Alexander Rich, A. Rich, 1983, Cell.

Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA.

R. Schwartz, B. Stollar, J. Rauch, 1981, Journal of immunology.

Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP).

D. Carnes, G. Mundy, G. Gutierrez, 2005, Bone.

Isolation and characterization of mutant bacteriophage T7 RNA polymerases.

D. Patra, E. Lafer, R. Sousa, 1992, Journal of molecular biology.

A Conserved Clathrin Assembly Motif Essential for Synaptic Vesicle Endocytosis

G. Augustine, Weihua Hao, J. Morgan, 2000, The Journal of Neuroscience.

A Role for an Hsp70 Nucleotide Exchange Factor in the Regulation of Synaptic Vesicle Endocytosis

Luis E Gimenez, Paul A. Oliphint, R. Sousa, 2013, The Journal of Neuroscience.

Intrinsically disordered proteins drive membrane curvature

M. Sherman, C. Hayden, E. Lafer, 2015, Nature Communications.

Yoga Therapy

E. Lafer, Margaret McCuiston, A. Swanson, 2021 .

Structural transitions of the RING1B C-terminal region upon binding the polycomb cbox domain.

A. Hinck, Chongwoo A. Kim, E. Lafer, 2008, Biochemistry.

Liquid-like assembly of VASP drives actin polymerization and bundling

A. Chandrasekaran, P. Rangamani, E. Lafer, 2022 .

Liquid-like VASP condensates drive actin polymerization and dynamic bundling

A. Chandrasekaran, P. Rangamani, E. Lafer, 2022, bioRxiv.

Clathrin Coat Disassembly Illuminates the Mechanisms of Hsp70 Force Generation

J. Valpuesta, A. Jin, R. Sousa, 2016, Nature Structural &Molecular Biology.

Synaptic Vesicle Recycling

E. Lafer, 2005, Science's STKE.

The synapse-specific phosphoprotein F1-20 is identical to the clathrin assembly protein AP-3.

S. Zhou, E. Lafer, J. Yang, 1993, The Journal of biological chemistry.

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids

R. Schwartz, B. Furie, B. Stollar, 1981, The Journal of experimental medicine.

The use of glycerol in crystallization of T7 RNA polymerase: Implications for the use of cosolvents in crystallizing flexible proteins

R. Sousa, E. Lafer, 1990 .

Author response: Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity

R. Jahn, Matija Krunić, E. Lafer, 2018 .

Reaction of systemic lupus erythematosus antinative DNA antibodies with native DNA fragments from 20 to 1,200 base pairs.

B. Stollar, E. Lafer, M. Papalian, 1980, The Journal of clinical investigation.

Anti-HIV IgM protects against mucosal SHIV transmission

S. Ratcliffe, E. Lafer, Liping Wang, 2018, AIDS.

Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP.

J. Laurence, A. Hedge, E. Lafer, 2008, Endocrinology.

Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism.

J. Barton, M. Tomasz, B. Stollar, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

D. Thirumalai, E. Lafer, Liping Wang, 2018, Nature Communications.

Z-DNA-specific antibodies in human systemic lupus erythematosus.

A. Rich, A. Nordheim, P. Schur, 1983, The Journal of clinical investigation.

Molecular Mechanisms of Steric Pressure Generation and Membrane Remodeling by Intrinsically Disordered Proteins

D. Thirumalai, C. Hayden, H. Cho, 2022, bioRxiv.

Conformation of a clathrin triskelion in solution.

R. Nossal, D. Sackett, M. L. Ferguson, 2006, Biochemistry.

The thumb subdomain of T7 RNA polymerase functions to stabilize the ternary complex during processive transcription.

E. Lafer, R. Sousa, G. Bonner, 1994, The Journal of biological chemistry.

Characterization of a set of T7 RNA polymerase active site mutants.

R. Sousa, E. Lafer, R. Sousa, 1994, The Journal of biological chemistry.

Model for the mechanism of bacteriophage T7 RNAP transcription initiation and termination.

D. Patra, R. Sousa, E. Lafer, 1992, Journal of molecular biology.

Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes

Alfred Nordheim, Alexander Rich, A. Rich, 1981, Nature.

ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.

H. Woo, R. Sousa, Jianwen Jiang, 2009, Biochemistry.

Monoclonal antibodies recognize different parts of Z-DNA.

A. Rich, A. Nordheim, B. Stollar, 1982, The Journal of biological chemistry.

PI 3‐kinase regulation of dopamine uptake

J. Javitch, A. Galli, T. Shippenberg, 2002, Journal of neurochemistry.

Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype*

D. Ghosh, B. Masters, R. Auchus, 2016, The Journal of Biological Chemistry.

The specificity of antibodies elicited by poly(dG).poly(dC).

B. Stollar, E. Lafer, 1984, Journal of biomolecular structure & dynamics.

Polycomb group targeting through different binding partners of RING1B C-terminal domain.

A. Hinck, P. Hart, Alexander B. Taylor, 2010, Structure.

Mitogen-Activated Protein Kinase Regulates Dopamine Transporter Surface Expression and Dopamine Transport Capacity

J. Javitch, B. Hope, A. Galli, 2003, The Journal of Neuroscience.

Clathrin–Protein Interactions

E. Lafer, 2002, Traffic.

Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses

R. Sousa, J. Morgan, E. Lafer, 2019, eNeuro.

Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy.

Ralph Nossal, R. Nossal, Paul D. Smith, 2006, Biophysical journal.

Ternary Complex of Transforming Growth Factor-β1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily*

A. Hinck, P. Sun, Zhongcheng Zou, 2010, The Journal of Biological Chemistry.

Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling

Troy C. Krzysiak, Morkos A. Henen, A. Hinck, 2016, Biochemistry.

Clathrin and synaptic vesicle endocytosis: studies at the squid giant synapse.

G. Augustine, C. Villalba-Galea, J. Morgan, 2006, Biochemical Society transactions.

The Races, Places, and Molecular Faces

G. Augustine, J. Morgan, E. Lafer, 2002 .

Synaptic vesicle endocytosis

G. Augustine, J. Morgan, E. Lafer, 2002, NeuroMolecular Medicine.

Uncoating of Clathrin-Coated Vesicles in Presynaptic Terminals Roles for Hsc70 and Auxilin

George J. Augustine, G. Augustine, J. Morgan, 2001, Neuron.

Negatively supercoiled plasmids contain left-handed Z-DNA segments as detected by specific antibody binding

Alfred Nordheim, Alexander Rich, L. J. Peck, 1982, Cell.

Isolation and characterization of Z-DNA binding proteins from wheat germ.

A. Rich, E. Lafer, B. Rosen, 1985, Biochemistry.

Structural basis of interdomain communication in the Hsc70 chaperone.

R. Sousa, Jianwen Jiang, K. Prasad, 2005, Molecular cell.

Antibodies specific for left-handed Z-DNA.

A. Rich, A. Nordheim, B. Stollar, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Supercoiling and left-handed Z-DNA.

L. J. Peck, J. Wang, A. Rich, 1983, Cold Spring Harbor symposia on quantitative biology.

Z-DNA and the polytene chromosome.

A. Rich, A. Nordheim, M. Pardue, 1983, Cold Spring Harbor symposia on quantitative biology.

Antibody recognition of Z-DNA.

A. Rich, A. Nordheim, B. Stollar, 1983, Cold Spring Harbor symposia on quantitative biology.

Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly.

A. Hinck, R. Sousa, E. Lafer, 2010, Journal of molecular biology.

A global benchmark study using affinity-based biosensors.

Yang Liu, Olan Dolezal, Eileen Lafer, 2009, Analytical biochemistry.

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity

R. Jahn, Matija Krunić, E. Lafer, 2018, eLife.

Liquid-like protein interactions catalyze assembly of endocytic vesicles

C. Hayden, E. Lafer, Liping Wang, 2019, Nature Cell Biology.

Clathrin Senses Membrane Curvature

C. Hayden, Avinash K. Gadok, E. Lafer, 2020, bioRxiv.

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

D. Thirumalai, E. Lafer, Liping Wang, 2018, Nature Communications.

Single crystals of bacteriophage T7 RNA polymerase

J. Rose, R. Sousa, E. Lafer, 1989, Proteins.

Unraveling protein-protein interactions in clathrin assemblies via atomic force spectroscopy.

R. Nossal, Paul D. Smith, A. Jin, 2013, Methods.

Keep the Traffic Moving: Mechanism of the Hsp70 Motor

R. Sousa, E. Lafer, 2006, Traffic.

Structural Biology and Crystallization Communications Crystallization of a Functionally Intact Hsc70 Chaperone

R. Sousa, Jianwen Jiang, E. Lafer, 2022 .

Clathrin triskelia show evidence of molecular flexibility.

R. Nossal, D. Sackett, S. Krueger, 2008, Biophysical journal.

BAR scaffolds drive membrane fission by crowding disordered domains

E. Lafer, J. Stachowiak, Wade F Zeno, 2018, bioRxiv.

Single crystals of a chimeric T7/T3 RNA polymerase with T3 promoter specificity and a nonprocessive T7 RNAP mutant.

B. Wang, W. Mcallister, Y. J. Chung, 1990, Journal of Biological Chemistry.

Preparation of crystals of T7 RNA polymerase suitable for high-resolution X-ray structure analysis

R. Sousa, E. Lafer, Bi-Cheng Wang, 1991 .

Membrane fission by protein crowding

C. Hayden, P. Rangamani, Avinash K. Gadok, 2017, Proceedings of the National Academy of Sciences.

Z-DNA-binding proteins in Escherichia coli purification, generation of monoclonal antibodies and gene isolation.

A. Rich, E. Lafer, R. Sousa, 1988, Journal of molecular biology.

Anti‐Z‐DNA antibody binding can stabilize Z‐DNA in relaxed and linear plasmids under physiological conditions.

A. Rich, E. Lafer, R. Sousa, 1985, The EMBO journal.

The ins and outs of membrane bending by intrinsically disordered proteins

Christopher T. Lee, P. Rangamani, E. Lafer, 2023, bioRxiv.

Molecular Mechanisms of Membrane Curvature Sensing by a Disordered Protein.

E. Lafer, Liping Wang, J. Stachowiak, 2019, Journal of the American Chemical Society.

A Role for the Clathrin Assembly Domain of AP180 in Synaptic Vesicle Endocytosis

G. Augustine, M. Womack, J. Morgan, 1999, The Journal of Neuroscience.

Clathrin Binding and Assembly Activities of Expressed Domains of the Synapse-specific Clathrin Assembly Protein AP-3 (*)

Weilan Ye, E. Lafer, 1995, The Journal of Biological Chemistry.

Monoclonal lupus autoantibodies.

R. Schwartz, B. Stollar, J. Rauch, 1982, Arthritis and rheumatism.

AFM visualization of clathrin triskelia under fluid and in air

R. Nossal, A. Jin, K. Prasad, 2010, FEBS letters.

Peptide from the C-terminal domain of tissue inhibitor of matrix metalloproteinases-2 (TIMP-2) inhibits membrane activation of matrix metalloproteinase-2 (MMP-2).

Xiaoping Xu, E. Lafer, B. Steffensen, 2011, Matrix biology : journal of the International Society for Matrix Biology.

The role of molecular chaperones in clathrin mediated vesicular trafficking

R. Sousa, E. Lafer, 2015, Front. Mol. Biosci..

Hsc70 rescues the synaptic vesicle trafficking defects caused by α-synuclein dimers

L. Bubacco, R. Sousa, J. Morgan, 2023, microPublication Biology.

The Physics of Entropic Pulling: A Novel Model for the Hsp70 Motor Mechanism

R. Sousa, E. Lafer, 2019, International journal of molecular sciences.

Liquid-like condensates mediate competition between actin branching and bundling

A. Chandrasekaran, P. Rangamani, E. Lafer, 2023, bioRxiv.

Lipid droplets as substrates for protein phase separation

David W. Taylor, S. Parekh, E. Lafer, 2023, bioRxiv.

Rapid-Fire Synaptic Vesicle Exocytosis

G. Augustine, J. Morgan, E. Lafer, 2001, Neuron.

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity

R. Jahn, Matija Krunić, E. Lafer, 2018, eLife.

Bacterially expressed F1‐20/AP‐3 assembles clathrin into cages with a narrow size distribution: Implications for the regulation of quantal size during neurotransmission

Weilan Ye, E. Lafer, W. Ye, 1995, Journal of neuroscience research.

Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype*

D. Ghosh, B. Masters, R. Auchus, 2016, The Journal of Biological Chemistry.

Unraveling protein-protein interactions in clathrin assemblies via atomic force spectroscopy.

R. Nossal, Paul D. Smith, A. Jin, 2013, Methods.

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

Gregory F Weber, L. Bonewald, M. Schwartz, 2012, Proceedings of the National Academy of Sciences.

Evaluation of competing J domain:Hsp70 complex models in light of existing mutational and NMR data

A. Hinck, Alexander B. Taylor, R. Sousa, 2011, Proceedings of the National Academy of Sciences.

Ubiquitin-driven protein condensation promotes clathrin-mediated endocytosis

J. Huibregtse, E. Lafer, Liping Wang, 2023, bioRxiv.

Liquid-like condensates mediate competition between actin branching and bundling

E. Lafer, Liping Wang, J. Stachowiak, 2024, Proceedings of the National Academy of Sciences of the United States of America.

Nuclear Magnetic Resonance Structural Mapping Reveals Promiscuous Interactions between Clathrin-Box Motif Sequences and the N-Terminal Domain of the Clathrin Heavy Chain

A. Hinck, R. Sousa, E. Lafer, 2015, Biochemistry.

Correction to Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling

Troy C. Krzysiak, Morkos A. Henen, A. Hinck, 2017, Biochemistry.