H. Furukawa

发表

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

Yusuke Nakamura, Kazuhiko Yamamoto, Tatsuhiko Tsunoda, 2003, Nature Genetics.

Protein Region Important for Regulation of Lipid Metabolism in Angiopoietin-like 3 (ANGPTL3)

Kenichi Yoshida, M. Shimamura, Mitsuru Ono, 2003, Journal of Biological Chemistry.

ANGPTL3 Decreases Very Low Density Lipoprotein Triglyceride Clearance by Inhibition of Lipoprotein Lipase*

Kenichi Yoshida, M. Shimamura, Mitsuru Ono, 2002, The Journal of Biological Chemistry.

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

Yusuke Nakamura, Kazuhiko Yamamoto, Tatsuhiko Tsunoda, 2003, Nature Genetics.

Specificity of Pyridinium Inhibitors of the Ubiquinone Reduction Sites in Mitochondrial Complex I*

H. Iwamura, H. Miyoshi, T. Watanabe, 1998, The Journal of Biological Chemistry.

Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.

A. Suzuki, R. Yamada, Kazuhiko Yamamoto, 2008, Journal of biochemistry.

Comparison of enzymatic properties between hPADI2 and hPADI4.

A. Suzuki, R. Yamada, Kazuhiko Yamamoto, 2005, Biochemical and biophysical research communications.

Impact of Adenosine Receptor Signaling and Metabolism on Pathophysiology in Patients with Chronic Heart Failure

H. Asanuma, Y. Liao, M. Asakura, 2007, Hypertension Research.

Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes.

M. Matsuda, M. Makishima, I. Shimomura, 2003, Biochemical and biophysical research communications.

Characterization of the 5′ Regulatory Region of the Mouse Angiopoietin-like Protein 4

M. Ono, K. Yoshida, H. Furukawa, 2004, Veterinary research communications.

Thienopyridine and benzofuran derivatives as potent anti-tumor agents possessing different structure-activity relationships.

T. Agatsuma, H. Furukawa, I. Hayakawa, 2004, Bioorganic & medicinal chemistry letters.

4-Hydroxy-3-methyl-6-phenylbenzofuran-2-carboxylic acid ethyl ester derivatives as potent anti-tumor agents.

T. Agatsuma, H. Furukawa, S. Naruto, 2004, Bioorganic & medicinal chemistry letters.

A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart.

K. Kawakami, N. Mochizuki, S. Takashima, 2007, The Journal of clinical investigation.

Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase

M. Matsuda, S. Yamashita, I. Shimomura, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Anti-Human Immunodeficiency Virus Type 1 Activity of R-95288, a Phosphodiester Hexadeoxyribonucleotide Modified by Dibenzyloxybenzyl and Hydroxyethyl Residues at the 5′- and 3′-Ends

T. Agatsuma, H. Furukawa, H. Hotoda, 1997 .

A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice Published, JLR Papers in Press, April 2, 2003. DOI 10.1194/jlr.M300031-JLR200

M. Shimamura, Mitsuru Ono, H. Furukawa, 2003, Journal of Lipid Research.

Protection of hu-PBL-SCID/beige mice from HIV-1 infection by a 6-mer modified oligonucleotide, R-95288.

T. Agatsuma, M. Koizumi, H. Furukawa, 1997, Antiviral research.

Activation of ecto-5'-nucleotidase in the blood and hearts of patients with chronic heart failure.

M. Hori, H. Asanuma, S. Sanada, 2008, Journal of cardiac failure.

Biologically active oligodeoxyribonucleotides. 5. 5'-End-substituted d(TGGGAG) possesses anti-human immunodeficiency virus type 1 activity by forming a G-quadruplex structure.

T. Agatsuma, M. Koizumi, H. Furukawa, 1998, Journal of medicinal chemistry.

Biologically active oligodeoxyribonucleotides--I: Syntheses and anti-HIV-1 activities of 5'-modified pentadecadeoxyribonucleotides.

H. Furukawa, K. Shimada, M. Kaneko, 1993, Nucleic acids symposium series.

Biologically active oligodeoxyribonucleotides. Part 11: The least phosphate-modification of quadruplex-forming hexadeoxyribonucleotide TGGGAG, bearing 3-and 5-end-modification, with anti-HIV-1 activity.

T. Agatsuma, M. Koizumi, H. Furukawa, 1998, Bioorganic & medicinal chemistry.

Antiviral and Biological Properties of Dimethoxytrityl-Linked Guanine-Rich Oligodeoxynucleotides that Inhibit Replication by Primary Clinical Human Immunodeficiency virus Type 1 Isolates

S. Oka, K. Shimada, H. Furukawa, 1997 .

Biologically active oligodeoxyribonucleotides--IX. Synthesis and anti-HIV-1 activity of hexadeoxyribonucleotides, TGGGAG, bearing 3'- and 5'-end-modification.

T. Agatsuma, M. Koizumi, H. Furukawa, 1997, Bioorganic & medicinal chemistry.

Biologically Active Oligodeoxyribonucleotides - IV 1 : Anti-HIV-1 Activity of Tgggag Having Hydrophobic Substituent at Its 5′-End via Phosphodiester Linkage §

M. Koizumi, K. Shimada, H. Furukawa, 1996 .

Jun Dimerization Protein 2 (JDP2), a Member of the AP-1 Family of Transcription Factor, Mediates Osteoclast Differentiation Induced by RANKL

Y. Kadono, Kozo Nakamura, Sakae Tanaka, 2003, The Journal of experimental medicine.

Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents.

T. Agatsuma, H. Furukawa, N. Hayashi, 2005, Bioorganic & medicinal chemistry letters.

A library synthesis of 4-hydroxy-3-methyl-6-phenylbenzofuran-2-carboxylic acid ethyl ester derivatives as anti-tumor agents.

T. Agatsuma, H. Furukawa, S. Naruto, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents.

T. Agatsuma, H. Furukawa, N. Hayashi, 2005, Bioorganic & medicinal chemistry letters.

Identification of 2′-Phosphodiesterase, Which Plays a Role in the 2-5A System Regulated by Interferon*

M. Yamashita, K. Ichikawa, H. Haruyama, 2004, Journal of Biological Chemistry.

Biologically Active Oligodeoxyribonucleotides - II1: Structure Activity Relationships of Anti-HIV-1 Pentadecadeoxyribonucleotides Bearing 5′-End-Modifications

Takemichi Nakamura, H. Furukawa, K. Shimada, 1994 .

Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs.

K. Taira, M. Miyagishi, T. Imanishi, 2002, Antisense & nucleic acid drug development.

Angptl3 regulates lipid metabolism in mice

T. Fujiwara, H. Horikoshi, M. Shimamura, 2002, Nature Genetics.

A New Fluoroquinolone Derivative Exhibits Inhibitory Activity against Human Immunodeficiency Virus Type 1 Replication

K. Shimada, H. Furukawa, S. Kimura, 1999, Chemotherapy.

Functional haplotypes of PADI 4 , encoding citrullinating enzyme peptidylarginine deiminase 4 , are associated with rheumatoid arthritis

Yusuke Nakamura, Kazuhiko Yamamoto, Tatsuhiko Tsunoda, 2003 .

CUL1, a component of E3 ubiquitin ligase, alters lymphocyte signal transduction with possible effect on rheumatoid arthritis

A. Sekine, T. Tsunoda, Y. Nakamura, 2005, Genes and Immunity.

Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor.

M. Matsuda, I. Shimomura, M. Shimamura, 2004, Biochemical and biophysical research communications.

Identification of genes related to heart failure using global gene expression profiling of human failing myocardium.

Hiroshi Asanuma, Atsushi Nakano, Yulin Liao, 2010, Biochemical and biophysical research communications.

Guanine-rich oligonucleotide modified at the 5' terminal by dimethoxytrityl residue inhibits HIV-1 replication by specific interaction with the envelope glycoprotein.

T. Agatsuma, H. Furukawa, T. Nishigaki, 1996, Antiviral research.

Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase Published, JLR Papers in Press, September 16, 2002. DOI 10.1194/jlr.C200010-JLR200

Kenichi Yoshida, Mitsuru Ono, H. Furukawa, 2002, Journal of Lipid Research.

A study to survey susceptible genetic factors responsible for troglitazone‐associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus

H. Haruyama, T. Koga, T. Izumi, 2003, Clinical pharmacology and therapeutics.

Identification of a phosphodiester hexanucleotide that inhibits HIV-1 infection in vitro on covalent linkage of its 5'-end with a dimethoxytrityl residue.

T. Agatsuma, H. Furukawa, S. Kimura, 1997, Antisense & nucleic acid drug development.

Mechanism of inhibition of HIV-1 infection in vitro by guanine-rich oligonucleotides modified at the 5' terminal by dimethoxytrityl residue.

T. Agatsuma, H. Furukawa, S. Kimura, 1994, Nucleic acids research.

Biologically Active Oligodeoxyribonucleotides. VII. Anti-HIV-1 Activity of Hexadeoxyribonucleotides Bearing 3′- and 5′-End-Modifications

M. Koizumi, K. Shimada, H. Furukawa, 1997 .

A Library Synthesis of 4-Hydroxy-3-methyl-6-phenylbenzofuran-2-carboxylic Acid Ethyl Ester Derivatives as Antitumor Agents.

T. Agatsuma, H. Furukawa, S. Naruto, 2004 .