M. Baggelaar

发表

Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification

Juan Zhou, Mario van der Stelt, H. Overkleeft, 2018, Nature Protocols.

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

B. Florea, M. van der Stelt, E. V. van Rooden, 2018, Front. Neurosci..

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

Zhanmin Lin, Thomas Hankemeier, Benjamin F. Cravatt, 2017, Science.

Catalytic asymmetric total synthesis of (S)-(-)-zearalenone, a novel lipoxygenase inhibitor.

B. Feringa, A. Minnaard, F. Dekker, 2013, Bioorganic & medicinal chemistry.

Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00029d

T. van der Wel, M. van der Stelt, H. Overkleeft, 2017, MedChemComm.

Comprehensive Analysis of Structure-Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors.

D. Boger, H. Overkleeft, B. Cravatt, 2015, Journal of medicinal chemistry.

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI‐101 prevents cisplatin‐induced nephrotoxicity

L. Heitman, A. Lichtman, K. Erdélyi, 2016, British journal of pharmacology.

Novel activity-based probes for N-acylethanolamine acid amidase.

H. Overkleeft, M. Artola, D. Piomelli, 2017, Chemical communications.

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

H. Overkleeft, T. Hankemeier, G. V. van Westen, 2019, ACS chemical biology.

A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

H. Overkleeft, T. van der Wel, M. van der Stelt, 2015, Journal of Lipid Research.

A natural substrate-based ﬂ uorescence assay for inhibitor screening on diacylglycerol lipase (cid:2)

Hepu Deng, M. Baggelaar, H. Overkleeft, 2015 .

Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles

A. Heck, Johannes F. Hevler, M. Baggelaar, 2022, Molecular & cellular proteomics : MCP.

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding.

H. Overkleeft, B. Cravatt, T. van der Wel, 2017, Journal of medicinal chemistry.

Total synthesis of the triglycosyl phenolic glycolipid PGL-tb1 from Mycobacterium tuberculosis.

H. Overkleeft, G. A. van der Marel, A. Minnaard, 2012, Angewandte Chemie.

2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain.

M. Maccarrone, M. van der Stelt, M. Baggelaar, 2018, Progress in lipid research.

Recent advancements in mass spectrometry–based tools to investigate newly synthesized proteins

A. Heck, M. Baggelaar, Wouter van Bergen, 2021, Current opinion in chemical biology.

Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition

H. Overkleeft, Juan Zhou, B. Cravatt, 2015, Proceedings of the National Academy of Sciences.

Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

J. Downward, E. Tate, M. Baggelaar, 2023, bioRxiv.

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons.

P. Chameau, H. Overkleeft, T. Hankemeier, 2015, Journal of the American Chemical Society.

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

H. de Vries, L. Heitman, M. Glass, 2017, Nature Communications.

Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6.

R. McGuire, H. Overkleeft, T. van der Wel, 2014, Journal of medicinal chemistry.

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain.

R. McGuire, H. Overkleeft, G. A. van der Marel, 2013, Angewandte Chemie.

ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

B. Barboni, B. Florea, M. Maccarrone, 2019, ACS chemical biology.

Activity-based protein profiling of diacylglycerol lipases

M. Baggelaar, 2017 .

A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation

Edward W. Tate, J. Downward, U. Eggert, 2023, bioRxiv.

ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

B. Barboni, B. Florea, M. Maccarrone, 2019, ACS chemical biology.

Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases.

H. Overkleeft, G. Marsicano, B. Florea, 2017, ACS chemical biology.

S-Palmitoylation during Retinoic Acid-Induced Neuronal Differentiation of SH-SY5Y Neuroblastoma Cells

M. Baggelaar, Samiksha Sardana, Anneroos E Nederstigt, 2023, Journal of proteome research.

Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6.

R. McGuire, H. Overkleeft, T. van der Wel, 2014, Journal of medicinal chemistry.

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding.

H. Overkleeft, B. Cravatt, T. van der Wel, 2017, Journal of medicinal chemistry.

A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation

M. Baggelaar, Cory A. Ocasio, Elisabeth M. Storck, 2024, Nature biotechnology.

Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

M. Baggelaar, Wouter van Bergen, Albert J. R. Heck, 2023, bioRxiv.

Competitive ABPP of Serine Hydrolases: A Case Study on DAGL-Alpha.

M. Baggelaar, Mario van der Stelt, 2017, Methods in molecular biology.

Development of an acid ceramidase activity-based probe.

H. Overkleeft, G. A. van der Marel, B. Florea, 2015, Chemical communications.