F. Rorsman

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Autoimmune polyendocrine syndrome type 1 (APS I) in Norway

M. Halonen, P. Eskelin, E. Husebye, 2001, Clinical endocrinology.

Efflux transporters in ulcerative colitis: Decreased expression of BCRP (ABCG2) and Pgp (ABCB1)

P. Artursson, G. Englund, A. Kindmark, 2007, Inflammatory bowel diseases.

Epidemiology and causes of death in a Swedish cohort of patients with autoimmune hepatitis

A. Bergquist, O. Weiland, H. Marschall, 2017, Scandinavian journal of gastroenterology.

Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease.

M. Landin-Olsson, J. Perheentupa, E. Husebye, 2004, The Journal of clinical endocrinology and metabolism.

Alternative splicing of the platelet-derived growth factor A-chain transcript occurs in normal as well as tumor cells and is conserved among mammalian species

C. Betsholtz, F. Rorsman, B. Matoskova, 1989, Molecular and cellular biology.

Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen.

L. Peltonen, N. Shikama, G. Åkerström, 2008, The New England journal of medicine.

AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype.

L. Peltonen, J. Partanen, M. Halonen, 2002, The Journal of clinical endocrinology and metabolism.

Accumulation of cadmium in pancreatic beta cells is similar to that of calcium in being stimulated by both glucose and high potassium.

P. Berggren, F. Rorsman, T. Nilsson, 1986, Biochimica et biophysica acta.

Autoantibodies against aromatic L-amino acid decarboxylase identifies a subgroup of patients with Addison's disease.

M. Halonen, E. Husebye, O. Kämpe, 2000, Journal of Clinical Endocrinology and Metabolism.

Low to moderate lifetime alcohol consumption is associated with less advanced stages of fibrosis in non-alcoholic fatty liver disease

R. Hultcrantz, M. Ekstedt, H. Marschall, 2017, Scandinavian journal of gastroenterology.

Increased IL‐17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model

H. Scott, L. Romani, J. Perheentupa, 2011, European journal of immunology.

Transjugular intrahepatic portosystemic shunt treatment of variceal bleeding in an unselected patient population

R. Nyman, F. Rorsman, P. Sangfelt, 2018, Scandinavian journal of gastroenterology.

Endovascular treatment of symptomatic Budd–Chiari syndrome – in favour of early transjugular intrahepatic portosystemic shunt

L. Eriksson, R. Nyman, F. Rorsman, 2016, European journal of gastroenterology & hepatology.

Endovascular treatment of acute and chronic portal vein thrombosis in patients with cirrhotic and non-cirrhotic liver

L. Eriksson, R. Nyman, F. Rorsman, 2016, Acta radiologica.

Placement of a transjugular intrahepatic portosystemic shunt in addition to recanalization of acute and chronic portomesenteric vein occlusions – a retrospective evaluation

L. Eriksson, R. Nyman, F. Rorsman, 2020, Acta radiologica open.

Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells.

G. Nilsson, L. Grimelius, J. Perheentupa, 2003, Journal of Clinical Endocrinology and Metabolism.

Characterization of the mouse PDGF A-chain gene. Evolutionary conservation of gene structure, nucleotide sequence and alternative splicing.

C. Betsholtz, F. Rorsman, 1992, Growth factors.

Modifications of the pancreatic beta-cell function after lowering their potassium content.

P. Bergsten, F. Rorsman, B. Hellman, 1986, Acta physiologica Scandinavica.

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects

C. Heldin, C. Betsholtz, E. Bongcam-Rudloff, 1988, Molecular and cellular biology.

Identification of tryptophan hydroxylase as an intestinal autoantigen

J. Haavik, L. Grimelius, J. Perheentupa, 1998, The Lancet.

Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins

C. Betsholtz, J. Scott, M. Bywater, 1988, Molecular and cellular biology.

Eosinophil granulocytes are activated during the remission phase of ulcerative colitis

O. Winqvist, M. Lampinen, F. Rorsman, 2005, Gut.

Different regulation of eosinophil activity in Crohn's disease compared with ulcerative colitis

O. Winqvist, M. Lampinen, F. Rorsman, 2008, Journal of leukocyte biology.

Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis.

J. Demoulin, J. Lennartsson, F. Houssiau, 2009, Arthritis and rheumatism.

The Transcription Factors SOX9 and SOX10 Are Vitiligo Autoantigens in Autoimmune Polyendocrine Syndrome Type I*

J. Perheentupa, E. Husebye, O. Kämpe, 2001, The Journal of Biological Chemistry.

Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma

F. Rorsman, J. Vessby, C. Barbier, 2021, Acta radiologica.

Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Mark S. Anderson, R. Fenton, G. Nordmark, 2016, Journal of the American Society of Nephrology : JASN.

AGPAT1 as a Novel Colonic Biomarker for Discriminating Between Ulcerative Colitis With and Without Primary Sclerosing Cholangitis

C. Lindskog, N. Eriksson, J. Wiśniewski, 2022, Clinical and translational gastroenterology.

Platelet-derived growth factor — Structural and functional aspects of the A-chain gene

C. Heldin, C. Betsholtz, B. Westermark, 1989 .

Circulating fatty acids from high-throughput metabolomics platforms as potential biomarkers of dietary fatty acids.

U. Risérus, F. Rorsman, J. Vessby, 2022, Clinical nutrition.

Clinical outcomes and sick leave in relation to UDCA treatment in Swedish patients with primary biliary cholangitis

H. Marschall, F. Rorsman, E. Nilsson, 2022, Scandinavian journal of gastroenterology.

Extrahepatic autoimmune diseases in primary biliary cholangitis: Prevalence and significance for clinical presentation and disease outcome

T. Berg, D. Semela, T. Schiano, 2020, Journal of gastroenterology and hepatology.

Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis.

T. Berg, D. Semela, T. Schiano, 2019, The American journal of gastroenterology.

Identification of complement C3 as an autoantigen in inflammatory bowel disease

B. Nilsson, K. Ekdahl, L. Grimelius, 2010, European journal of gastroenterology & hepatology.

Downregulated eosinophil activity in ulcerative colitis with concomitant primary sclerosing cholangitis

M. Lampinen, F. Rorsman, A. Wanders, 2018, Journal of leukocyte biology.

Tissue factor in ulcerative colitis, with and without concomitant primary sclerosing cholangitis

A. Siegbahn, M. Lampinen, F. Rorsman, 2019, Upsala journal of medical sciences.

Platelet-derived growth factor (PDGF) A-chain mRNA heterogeneity generated by the use of alternative promoters and alternative polyadenylation sites.

C. Betsholtz, F. Rorsman, P. Levéen, 1992, Growth factors.

The human islet amyloid polypeptide (IAPP) gene

C. Betsholtz, P. Westermark, G. Stenman, 1990, FEBS letters.

Structure of Cat Islet Amyloid Polypeptide and Identification of Amino Acid Residues of Potential Significance for Islet Amyloid Formation

C. Betsholtz, M. Murtaugh, P. Westermark, 1990, Diabetes.

Structural and functional aspects of platelet-derived growth factor and its role in the pathogenesis of glioblastoma.

C. Heldin, C. Betsholtz, M. Nistér, 1989, Molecular and chemical neuropathology.

High Serum sCD40 and a Distinct Colonic T Cell Profile in Ulcerative Colitis Associated With Primary Sclerosing Cholangitis

M. Lampinen, F. Rorsman, A. Wanders, 2018, Journal of Crohn's & colitis.

Sublocalization of the human PDGF A-chain gene to chromosome 7, band q11.23, by in situ hybridization.

C. Betsholtz, G. Stenman, F. Rorsman, 1988, Experimental cell research.

Islet amyloid polypeptide (IAPP): structure of its cDNA and gene and the identification of species differences of importance for islet amyloid formation.

Kenneth H. Johnson, C. Betsholtz, P. Westermark, 1991 .

Autoantibodies in autoimmune polyglandular syndrome type I patients react with major brain neurotransmitter systems

T. Hökfelt, J. Mulder, T. Harkany, 2009, The Journal of comparative neurology.

Active cytomegalovirus infection diagnosed by real-time PCR in patients with inflammatory bowel disease: a prospective, controlled observational study*

F. Rorsman, A. Rönnblom, M. Thörn, 2016, Scandinavian journal of gastroenterology.

Tryptophan hydroxylase autoantibodies and intestinal disease in autoimmune polyendocrine syndrome type 1

O. Kämpe, O. Ekwall, F. Rorsman, 1999, The Lancet.

Monitoring dominant strictures in primary sclerosing cholangitis with brush cytology and FDG-PET.

A. Bergquist, A. Sundin, F. Rorsman, 2014, Journal of hepatology.

Aromatic-L-amino-acid decarboxylase, a pyridoxal phosphate-dependent enzyme, is a beta-cell autoantigen.

E. Husebye, O. Kämpe, F. Karlsson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

L-aromatic amino acid decarboxylase, a plp-containing autoantigen in beta-cells

E. Husebye, F. Karlsson, O. Winqvist, 1995 .

Adrenal autoantibodies and organ‐specific autoimmunity in patients with Addison's disease

E. Husebye, O. Kämpe, F. Karlsson, 1996, Clinical endocrinology.

Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I.

J. Haavik, J. Perheentupa, E. Husebye, 2000, Biochemical and biophysical research communications.

Antibodies against hair follicles are associated with alopecia totalis in autoimmune polyendocrine syndrome type I.

J. Perheentupa, E. Husebye, O. Kämpe, 1999, The Journal of investigative dermatology.

Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I.

M. Manns, T. Tuomi, A. Miettinen, 2004, The Journal of clinical endocrinology and metabolism.

Autoantibodies against Aromatic L-amino Acid Decarboxylase in Autoimmune Polyendocrine Syndrome Type I* Subjects and Methods Subjects

T. Tuomi, M. Landin-Olsson, J. Perheentupa, 2022 .

Autoimmune adrenal insufficiency: recognition and management.

O. Kämpe, O. Winqvist, F. Rorsman, 2000, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.

Pteridin-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type I.

J. Haavik, J. Perheentupa, E. Husebye, 2000, The Journal of clinical endocrinology and metabolism.

Cytochrome P450IA2 and aromatic l‐amino acid decarboxylase are hepatic autoantigens in autoimmune polyendocrine syndrome type I

O. Kämpe, O. Winqvist, F. Rorsman, 1997, FEBS letters.

Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells.

P. Artursson, L. Lazorova, G. Englund, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Islet amyloid polypeptide (IAPP):cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus.

C. Betsholtz, E. Wilander, P. Westermark, 1989, Experimental cell research.

Impaired Autoimmune T Helper 17 Cell Responses Following DNA Vaccination against Rat Experimental Autoimmune Encephalomyelitis

O. Kämpe, Å. Andersson, A. Flores-Morales, 2008, PloS one.

Autoantibodies linked to autoimmune polyendocrine syndrome type I are prevalent in Down syndrome

G. Annéren, O. Kämpe, O. Ekwall, 2006, Acta paediatrica.

No evidence for autoimmunity as a major cause of the empty sella syndrome.

P. Crock, K. Brismar, O. Kämpe, 2004, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus.

L. Rönnblom, A. Lindahl, P. Bird, 2002, Biochemical and biophysical research communications.

Analogous alternative splicing

C. Betsholtz, B. Westermark, A. Östman, 1990, Nature.

Immunoreactivity against goblet cells in patients with inflammatory bowel disease

L. Grimelius, O. Kämpe, G. Portela-Gomes, 2008, Inflammatory bowel diseases.

Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease

P. Hockings, H. Ahlström, U. Risérus, 2022, Frontiers in Medicine.

Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type I and Addison's disease.

O. Kämpe, F. Karlsson, O. Winqvist, 1993, The Journal of clinical investigation.

Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen

C. Janson, F. Pontén, J. Haavik, 2009, Proceedings of the National Academy of Sciences.

Autoantibodies to glutathione S-transferase theta 1 in patients with primary sclerosing cholangitis and other autoimmune diseases.

C. Bruder, J. Dumanski, O. Kämpe, 2008, Journal of autoimmunity.

Malabsorption due to cholecystokinin deficiency in a patient with autoimmune polyglandular syndrome type I.

O. Kämpe, O. Ekwall, F. Rorsman, 2001, The New England journal of medicine.

Autoantibodies to alpha-fodrin in primary Sjögren's syndrome and SLE detected by an in vitro transcription and translation assay.

M. Taussig, L. Rönnblom, G. Nordmark, 2003, Clinical and experimental rheumatology.

Inhibition of aromatic l‐amino acid decarboxylase activity by human autoantibodies

T. Flatmark, J. Haavik, E. Husebye, 2000, Clinical and experimental immunology.

Autoimmune Adrenal Insufficiency

O. Kämpe, O. Winqvist, F. Rorsman, 2000, BioDrugs.

Impact on follow‐up strategies in patients with primary sclerosing cholangitis

C. Strassburg, A. Bergquist, A. Floreani, 2022, Liver international : official journal of the International Association for the Study of the Liver.

Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

F. Heindryckx, H. Lennernäs, M. Hedeland, 2022, BMJ Open.

Effects of Tumor Necrosis Factor Antagonists in Patients With Primary Sclerosing Cholangitis.

A. Bergquist, R. Chapman, S. Vermeire, 2020, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Liver cirrhosis turns life into an unpredictable roller coaster: A qualitative interview study

M. Hjorth, F. Rorsman, D. Sjöberg, 2020, Journal of clinical nursing.

Nurse-led clinic for patients with liver cirrhosis—effects on health-related quality of life: study protocol of a pragmatic multicentre randomised controlled trial

M. Hjorth, F. Rorsman, Sophie Langenskiöld, 2018, BMJ Open.

Bivariate MR imaging biomarker to improve prediction of advanced fibrosis in subjects with biopsy proven NAFDL

M. Lubberink, P. Hockings, H. Ahlström, 2020 .

The human platelet-derived growth factor α chain (PDGFA) gene maps to chromosome 7p22

K. Huebner, C. Betsholtz, G. Stenman, 1992 .

Appearance of hepatobiliary diseases in a population‐based cohort with inflammatory bowel diseases (Inflammatory Bowel Disease Cohort of the Uppsala Region)

F. Rorsman, A. Rönnblom, T. Holmström, 2015, Journal of gastroenterology and hepatology.

Identification of a novel staining pattern of bile duct epithelial cells in primary sclerosing cholangitis

L. Grimelius, G. Portela-Gomes, O. Ekwall, 2010, Inflammatory bowel diseases.