J. Schickel

发表

AIRE expression controls the peripheral selection of autoreactive B cells

C. Cunningham-Rundles, E. Meffre, P. Utz, 2019, Science Immunology.

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

E. Meffre, F. Candotti, M. C. Castiello, 2015, The Journal of clinical investigation.

CD19 controls Toll-like receptor 9 responses in human B cells.

İ. Reisli, J. Franco, C. Cunningham-Rundles, 2016, The Journal of allergy and clinical immunology.

Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation

A. Soley, A. Korganow, T. Martin, 2015, Immunity, inflammation and disease.

Title: Correction of autoimmune IL2RA mutations in primary human T cells u sing non - viral genome targeting

Channabasavaiah B. Gurumurthy, Rolen M. Quadros, A. May, 2017 .

Reprogramming human T cell function and specificity with non-viral genome targeting

Channabasavaiah B. Gurumurthy, Rolen M. Quadros, A. Ashworth, 2017, bioRxiv.

Chronic bacterial infection activates autoreactive B cells and induces isotype switching and autoantigen‐driven mutations

Sophie Jung, A. Korganow, R. Brink, 2016, European journal of immunology.

Carabin Protects Against Cardiac Hypertrophy by Blocking Calcineurin, Ras, and Ca2+/Calmodulin-Dependent Protein Kinase II Signaling

F. Lezoualc’h, A. Varin, C. Deloménie, 2014, Circulation.

Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

A. Soley, A. Korganow, M. Decossas, 2012, EMBO molecular medicine.

B Cell Signature during Inactive Systemic Lupus Is Heterogeneous: Toward a Biological Dissection of Lupus

D. Dembélé, G. Blaison, A. Korganow, 2011, PloS one.

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production.

E. Meffre, A. Murphy, R. Flavell, 2017, Blood.

Malaria-susceptible West African Children Atypical Memory B Cells in the V Gene Repertoires of Classical And

E. Meffre, J. Skinner, M. Waisberg, 2022 .

The V Gene Repertoires of Classical and Atypical Memory B Cells in Malaria-Susceptible West African Children

E. Meffre, J. Skinner, M. Waisberg, 2015, The Journal of Immunology.

Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF

J. Gottenberg, J. Sibilia, G. Alsaleh, 2011, European journal of immunology.

Carabin Protects Against Cardiac Hypertrophy by Blocking Calcineurin, Ras and CaMKII Signaling

A. Varin, C. Deloménie, J. Schickel, 2014 .

PTPN22 inhibition resets defective human central B cell tolerance.

E. Meffre, R. Flavell, T. Strowig, 2016, Science immunology.

PTPN22 inhibition resets defective human central B cell tolerance

E. Meffre, R. Flavell, T. Strowig, 2016, Science Immunology.

PTPN 22 inhibition resets defective human central B cell tolerance

E. Meffre, R. Flavell, Christopher, 2016 .

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

J. B. Oliveira, J. Hughes, J. McElwee, 2014, Science.

Reprogramming human T cell function and specificity with non-viral genome targeting

A. Ashworth, A. May, J. Weissman, 2017, bioRxiv.

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

J. Orange, E. Meffre, W. Pickl, 2019, Nature Communications.

Circulating Human CD27−IgA+ Memory B Cells Recognize Bacteria with Polyreactive Igs

M. V. van Zelm, J. V. van Dongen, E. Meffre, 2015, The Journal of Immunology.

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.

L. Notarangelo, J. Walter, W. Al-Herz, 2015, Immunity.

Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis

Ruth R. Montgomery, E. Meffre, E. Gelfand, 2019, Science Translational Medicine.

Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses

C. Cunningham-Rundles, K. Sullivan, E. Meffre, 2019, The Journal of allergy and clinical immunology.

Positive and negative selection shape the human naive B cell repertoire

K. Schwarz, A. Schulz, E. Meffre, 2021, The Journal of clinical investigation.

Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria

J. Casanova, C. Picard, S. Holland, 2017, The Journal of experimental medicine.

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.

M. van der Burg, L. Notarangelo, J. Walter, 2016, The Journal of clinical investigation.

Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.

E. Meffre, A. Soley, Sophie Jung, 2018, JCI insight.

TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development.

S. Rosengren, R. Geha, C. Cunningham-Rundles, 2015, The Journal of allergy and clinical immunology.

Reprogramming human T cell function and specificity with non-viral genome targeting

J. Weissman, M. Leonetti, S. Hughes, 2018, Nature.

Reprogramming human T cell function and specificity with non-viral genome targeting

Jonathan S. Weissman, Alan Ashworth, Antoni Ribas, 2017, Nature.

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.

M. van der Burg, L. Notarangelo, J. Walter, 2016, The Journal of clinical investigation.

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.

L. Notarangelo, J. Walter, W. Al-Herz, 2015, Immunity.

Carabin Protects Against Cardiac Hypertrophy by Blocking Calcineurin, Ras, and Ca2+/Calmodulin-Dependent Protein Kinase II Signaling

F. Lezoualc’h, A. Varin, C. Deloménie, 2014, Circulation.

TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development.

S. Rosengren, R. Geha, C. Cunningham-Rundles, 2015, The Journal of allergy and clinical immunology.

TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance

A. Hoischen, L. Staudt, E. Meffre, 2023, The Journal of experimental medicine.

CD19 controls Toll-like receptor 9 responses in human B cells.

J. Franco, C. Cunningham-Rundles, E. Meffre, 2016, The Journal of allergy and clinical immunology.