D. Greenhalgh

D. Roop, J. Rothnagel, L. Nanney, 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Effects of 5-fluorouracil on cytotoxicity and RNA metabolism in human colonic carcinoma cells

J. H. Parish, D. Greenhalgh, 2004, Cancer Chemotherapy and Pharmacology.

Critical Aspects of Initiation, Promotion, and Progression in Multistage Epidermal Carcinogenesis

S. Yuspa, T. Tennenbaum, D. Greenhalgh, 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.

D. Roop, D. Greenhalgh, H. Hennings, 1991, Environmental health perspectives.

The malignant conversion step of mouse skin carcinogenesis.

D. Roop, S. Yuspa, D. Greenhalgh, 1990, Environmental health perspectives.

Analysis of the rasH oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines.

S. Yuspa, J. Lacal, S. Reynolds, 1987, Carcinogenesis.

Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Cancer research.

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Molecular carcinogenesis.

Two oncogenes, v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma.

S. Yuspa, D. Greenhalgh, A. Player, 1990, Proceedings of the National Academy of Sciences of the United States of America.

12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.

D. Roop, D. Greenhalgh, Xiaojing Wang, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Epidermal expression of transforming growth factor‐α in transgenic mice: Induction of spontaneous and 12‐O‐tetradecanoylphorbol‐13‐acetate‐induced papillomas via a mechanism independent of Ha‐ras activation or overexpression

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, Molecular carcinogenesis.

Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting.

D. Roop, D. Greenhalgh, 1994, Advances in cancer research.

Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21WAF-induced differentiation triggered by GSK3β inactivation and reduced AKT activity

J. Quinn, Hong Wu, D. Greenhalgh, 2008, Journal of Cell Science.

PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.

J. Quinn, Hong Wu, D. Greenhalgh, 2006, Cancer research.

Cooperation between Ha‐ras and fos or transforming growth factor α overcomes a paradoxic tumor‐inhibitory effect of p53 loss in transgenic mouse epidermis

L. Donehower, D. Roop, D. Greenhalgh, 2000, Molecular carcinogenesis.

Epidermis: an attractive target tissue for gene therapy.

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, The Journal of investigative dermatology.

Transgenic models of skin diseases.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Archives of dermatology.

Analysis of centrosome abnormalities and angiogenesis in epidermal‐targeted p53172H mutant and p53‐knockout mice after chemical carcinogenesis: Evidence for a gain of function

D. Roop, L. Zhong, B. Brinkley, 1998, Molecular carcinogenesis.

Up-regulation of keratin 17 expression in human HaCaT keratinocytes by interferon-gamma.

B. Bonnekoh, T. Krieg, J. Geisel, 1995, The Journal of investigative dermatology.

Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.

R. Schlegel, D. Roop, J. Rothnagel, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.

D. Roop, J. Rothnagel, D. Greenhalgh, 1990, The Journal of investigative dermatology.

TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.

D. Roop, D. Greenhalgh, X. Wang, 1995, Oncogene.

Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.

C. Fisher, D. Roop, J. Rothnagel, 1993, Oncogene.

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

R. Derynck, D. Roop, T. Krieg, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model.

B. Bonnekoh, D. Roop, T. Krieg, 1998, The Journal of investigative dermatology.

SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene.

C. Sutter, S. Yuspa, D. Greenhalgh, 1994, Carcinogenesis.

Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis

D. Medina, D. Roop, L. Zhong, 1998, Oncogene.

Epidermal ROCK2-induces AKT1/GSK3β/β-catenin, NFκB and dermal tenascin-C; but enhanced differentiation and p53/p21 inhibit papilloma.

M. Olson, D. Greenhalgh, S. F. Masre, 2020, Carcinogenesis.

Development of transgenic mouse models of skin carcinogenesis: potential applications.

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, Progress in clinical and biological research.

Cotransfection of HPV-18 and v-fos DNA induces tumorigenicity of primary human keratinocytes.

R. Schlegel, D. Greenhalgh, J. Meck, 1993, Virology.

Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox.

D. Greenhalgh, Dennis R. Roop, Xiao-Jing Wang, 1996, The journal of investigative dermatology. Symposium proceedings.