S. Gu

Jean X. Jiang, Haoran Xu, Xiaodun Wang, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Beyond the Channels: Adhesion Functions of Aquaporin 0 and Connexin 50 in Lens Development

Jean X. Jiang, S. Gu, Yumeng Quan, 2022, Frontiers in Cell and Developmental Biology.

Aquaporin-0 targets interlocking domains to control the integrity and transparency of the eye lens.

Jean X. Jiang, S. Gu, S. Biswas, 2014, Investigative ophthalmology & visual science.

Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation

Jean X. Jiang, S. Gu, Rui Hua, 2022, Frontiers in Cell and Developmental Biology.

Development of a potent embryonic chick lens model for studying congenital cataracts in vivo

Jean X. Jiang, S. Gu, K. Varadaraj, 2021, Communications biology.

Regulation of Lens Connexin 45.6 by Apoptotic Protease, Caspase-3

Jean X. Jiang, S. Gu, J. X. Jiang, 2001, Cell communication & adhesion.

Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress

Jean X. Jiang, F. Acosta, Jingruo Zhang, 2022, bioRxiv.

Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5

T. Guda, Jean X. Jiang, M. Riquelme, 2022, Bone Research.

Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading

T. Guda, Jean X. Jiang, M. Riquelme, 2021, bioRxiv.

Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

Jean X. Jiang, M. Riquelme, S. Gu, 2021, iScience.

Identification of a Disulfide Bridge Important for Transport Function of SNAT4 Neutral Amino Acid Transporter

Jean X. Jiang, B. Nicholson, S. Gu, 2013, PloS one.

Characterization of an N-system Amino Acid Transporter Expressed in Retina and Its Involvement in Glutamine Transport*

Jean X. Jiang, H. Roderick, P. Camacho, 2001, The Journal of Biological Chemistry.

Identification and characterization of an amino acid transporter expressed differentially in liver.

H. Roderick, P. Camacho, S. Gu, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of astrocyte hemichannel improves recovery from spinal cord injury

Michael J. Mader, Jean X. Jiang, V. Bartanusz, 2021, JCI insight.

Connexin 43 Channels Are Essential for Normal Bone Structure and Osteocyte Viability

Mark L. Johnson, Sherry L. Werner, T. Guda, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone

Jean X. Jiang, F. Acosta, Jingruo Zhang, 2022, Cell & Bioscience.

Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation

Jean X. Jiang, Zhengping Hu, T. W. White, 2017, Scientific Reports.

Mechanotransduction via the coordinated actions of integrins, PI3K signaling and Connexin hemichannels

Jean X. Jiang, M. Riquelme, S. Gu, 2021, Bone Research.

Mechanical Loading Stimulates Expression of Connexin 43 in Alveolar Bone Cells in the Tooth Movement Model

Jean X. Jiang, D. Pavlin, S. Gu, 2006, Cell communication & adhesion.

Regional changes of AQP0-dependent square array junction and gap junction associated with cortical cataract formation in the Emory mutant mouse.

Jean X. Jiang, S. Gu, S. Biswas, 2014, Experimental eye research.

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Jean X. Jiang, T. W. White, M. Riquelme, 2019, Investigative ophthalmology & visual science.

Lens Connexin 50 and AQP 0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Jean X. Jiang, T. W. White, M. Riquelme, 2019 .

Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50

Jean X. Jiang, Ji Xu, B. Nicholson, 2011, Journal of Cell Science.

Studying macrophage activation in immune-privileged lens through CSF-1 protein intravitreal injection in mouse model

Jean X. Jiang, F. Acosta, S. Gu, 2021, STAR Protocols.

Data on Connexin 43 hemichannels regulation of cellular redox in lens

Jean X. Jiang, S. Gu, Changrui Wu, 2021, Data in brief.

Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix.

Travis D. Eliason, Jean X. Jiang, D. Nicolella, 2020, Matrix biology : journal of the International Society for Matrix Biology.

Gene promoter of apoptosis inhibitory protein IAP2: identification of enhancer elements and activation by severe hypoxia.

M. Venkatachalam, S. Gu, Senlin Li, 2002, The Biochemical journal.

Jean X. Jiang, Xiaodun Wang, S. Gu, 2018, JBMR plus.

Development of a potent embryonic chick lens model for studying congenital cataracts in vivo

Jean X. Jiang, S. Gu, Zhen Li, 2021, Communications Biology.

A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal mapping, genomic structure, expression, and functional characterization.

R. Leach, S. Gu, S Gu, 2001, Genomics.

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin.

L. Bonewald, Jean X. Jiang, E. Sprague, 2005, Molecular biology of the cell.

Gap junction- and hemichannel-independent actions of connexins.

Jean X. Jiang, S. Gu, J. Jiang, 2005, Biochimica et biophysica acta.

Connexin Controls Cell-Cycle Exit and Cell Differentiation by Directly Promoting Cytosolic Localization and Degradation of E3 Ligase Skp2.

Jean X. Jiang, T. W. White, S. Gu, 2015, Developmental cell.

Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage

Jean X. Jiang, S. Gu, Changrui Wu, 2021, Redox biology.

Protein kinase A activation alleviates cataract formation via increased gap junction intercellular communication

Jean X. Jiang, S. Gu, Hongyun Cheng, 2023, iScience.

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Zhengping Hu, M. Riquelme, S. Gu, 2018, The Journal of Biological Chemistry.

Differential Regulation of Amino Acid Transporter SNAT3 by Insulin in Hepatocytes*

S. Gu, Jean X. Jiang, Carla J Villegas, 2005, Journal of Biological Chemistry.

Residue cysteine 232 is important for substrate transport of neutral amino acid transporter, SNAT4.

B. Nicholson, S. Gu, R. Padmanabhan, 2012, International journal of biochemistry and molecular biology.

Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis

Luzhe Sun, M. Riquelme, S. Gu, 2016 .

Membrane Topological Structure of Neutral System N/A Amino Acid Transporter 4 (SNAT4) Protein*

S. Gu, Qian Shi, R. Padmanabhan, 2011, The Journal of Biological Chemistry.

The second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation, and adhesion molecule expression

S. Gu, Yumeng Quan, Guangyan Wang, 2023, The Journal of biological chemistry.

Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation

Zhengping Hu, T. W. White, M. Riquelme, 2017, Scientific Reports.

Identification and characterization of an amino acid transporter expressed differentially in liver

H. Roderick, P. Camacho, S. Gu, 2000 .

Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

M. Riquelme, S. Gu, Hongyun Cheng, 2021, iScience.

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

Gregory F Weber, L. Bonewald, M. Schwartz, 2012, Proceedings of the National Academy of Sciences.

Connexin hemichannels drive lactation-induced osteocyte acidification and perilacunar-canalicular remodeling

T. Guda, S. Gu, Rui Hua, 2024, Cell reports.

Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults

M. Riquelme, S. Gu, Yumeng Quan, 2024, Redox biology.

Amino Acid Residue Val362 Plays a Critical Role in Maintaining the Structure of C Terminus of Connexin 50 and in Lens Epithelial-fiber Differentiation*

S. Gu, J. Lauer, Qian Shi, 2010, The Journal of Biological Chemistry.