J. Barber

发表

Identification and quantification of blood–brain barrier transporters in isolated rat brain microvessels

A. Rostami-Hodjegan, B. Achour, Narciso Couto, 2018, Journal of neurochemistry.

GASP and FASP are Complementary for LC–MS/MS Proteomic Analysis of Drug‐Metabolizing Enzymes and Transporters in Pig Liver

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2018, Proteomics.

Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients.

A. Rostami-Hodjegan, B. Achour, S. Neuhoff, 2019, Molecular pharmaceutics.

Hoechst 33258 and its complex with the oligonucleotide d(CGCGAATTCGCG) 2: 1H NMR assignments and dynamics

G. Morris, K. Douglas, J. Parkinson, 1992 .

Minor-groove recognition of the self-complementary duplex d(CGCGAATTCGCG)2 by Hoechst 33258: a high-field NMR study.

K. Douglas, J. Parkinson, J. Barber, 1990, Biochemistry.

16-membered macrolide antibiotics: a review.

Ana-Marija Cikoš, M. Mladenović, Nevena Stanković, 2017, International journal of antimicrobial agents.

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics.

P. Wright, A. Rostami-Hodjegan, B. Achour, 2019, Molecular pharmaceutics.

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine

Pamela J Davies, G. Warhurst, A. Rostami-Hodjegan, 2020, Drug Metabolism and Disposition.

Isolation, purification and nuclear magnetic resonance spectra of pulvilloric acid

J. Barber, S. Bradley, Sa Pope, 1986, Mycotoxin Research.

Mass Spectrometry of Human Transporters.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2020, Annual review of analytical chemistry.

Scaling Factors for Clearance in Adult Liver Cirrhosis

A. Rostami-Hodjegan, B. Achour, V. Athwal, 2020, Drug Metabolism and Disposition.

Mass spectrometry‐based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin

N. Couto, A. Rostami-Hodjegan, B. Achour, 2020, FEBS letters.

Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

A. Rostami-Hodjegan, B. Achour, Francesco Lanucara, 2017, Drug Metabolism and Disposition.

Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard.

A. Rostami-Hodjegan, B. Achour, M. Russell, 2020, Journal of pharmaceutical and biomedical analysis.

A diastereoselective synthesis of the polyketide antibiotic citrinin using toluate anion chemistry

J. Staunton, J. Barber, Michael R. Wilkinson, 1986 .

Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs

Yuan Chen, J. Mao, A. Rostami-Hodjegan, 2022, Clinical Pharmacokinetics.

Systematic approach to understanding macrolide-ribosome interactions: NMR and modeling studies of oleandomycin and its derivatives.

Sanja Koštrun, J. Barber, P. Novak, 2006, The journal of physical chemistry. A.

Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model

M. Clench, J. Sidaway, Esther Karunakaran, 2020, Drug Metabolism and Disposition.

Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs

Yuan Chen, J. Mao, A. Rostami-Hodjegan, 2022, Clinical Pharmacokinetics.

Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Journal of pharmaceutical sciences.

Quantitative Proteomics of Hepatic Drug‐Metabolizing Enzymes and Transporters in Patients With Colorectal Cancer Metastasis

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Clinical pharmacology and therapeutics.

Computational Studies on Selected Macrolides Active against Escherichia coli Combined with the NMR Study of Tylosin A in Deuterated Chloroform

A. Oates, A. McBain, Ana-Marija Cikoš, 2022, Molecules.

Hepatic Scaling Factors for In Vitro–In Vivo Extrapolation of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis

S. Peters, A. Rostami-Hodjegan, B. Achour, 2021, Drug Metabolism and Disposition.

The biosynthesis of citrinin by Penicillium citrinum

M. Garson, J. Staunton, J. Barber, 1981 .

Full assignments of the 1H and 13C NMR spectra of sodium fusidate in organic and aqueous media

G. Morris, J. Barber, L. Lian, 1989 .

The first protoberberine alkaloid analogue with in vivo antimalarial activity

A. Satoskar, J. Barber, R. Waigh, 1994 .

Conformational study of tylosin A in water and full assignments of 1H and 13C spectra of tylosin A in D2O and tylosin B in CDCl3

J. Aguilar, R. Bryce, J. Barber, 2017, Magnetic resonance in chemistry : MRC.

New insights into polyketide metabolism; the use of protium as a tracer in the biosynthesis of citrinin by Penicillium citrinum

J. Staunton, J. Barber, 1980 .

The structure of citrinin in vivo

T. Howard, J. Barber, J. L. Cornford, 1987 .

Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice.

Jill Barber, Amin Rostami-Hodjegan, Brahim Achour, 2019, Pharmacology & therapeutics.

Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution.

P. A. Gorry, G. Morris, J. Barber, 2007, The journal of physical chemistry. A.

Biosynthesis of citrinin in Penicillium citrinum: advanced precursor studies using 2H nuclear magnetic resonance spectroscopy

J. Staunton, J. Barber, 1980 .

Citrinin biosynthesis in P. citrinum: incorporation of a deuterium-labelled advanced precursor in the presence of a specific inhibitor of an early step

J. Staunton, J. Barber, 1980 .

Free and bound state structures of 6-O-methyl homoerythromycins and epitope mapping of their interactions with ribosomes.

J. Plavec, Ana-Marija Cikoš, J. Barber, 2009, Bioorganic & medicinal chemistry.

A Systematic Approach to Understanding Ribosome-Macrolide Interactions: NMR and Modeling Studies of Oleandomycin and Its Derivatives

Sanja Koštrun, J. Barber, P. Novak, 2006 .

The role of glutathione reductase and related enzymes on cellular redox homoeostasis network.

Narciso Couto, J. Barber, J. Wood, 2016, Free radical biology & medicine.

Structural studies on erythromycin A enol ether: full assignments of the 1H and 13C NMR spectra

J. Parkinson, J. Barber, P. Buxton, 1995 .

The structure of erythromycin A in [2H6]DMSO and buffered D2O: full assignments of the 1H and 13C NMR spectra

G. Morris, L. Lian, J. I. Gyi, 1991 .

Effects of gentamicin on the proteomes of aerobic and oxygen-limited Escherichia coli.

S. Gaskell, Zubida M. Al-Majdoub, J. Barber, 2013, Journal of medicinal chemistry.

Partition and turnover of glutathione reductase from Saccharomyces cerevisiae: a proteomic approach.

N. Malys, S. Gaskell, Narciso Couto, 2013, Journal of proteome research.

Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

T. Goosen, A. Rostami-Hodjegan, B. Achour, 2017, Drug Metabolism and Disposition.

Matrix-assisted laser desorption/ionisation mass spectrometric response factors of peptides generated using different proteolytic enzymes.

S. Gaskell, Narciso Couto, J. Barber, 2011, Journal of mass spectrometry : JMS.

Detection of low-abundance protein phosphorylation by selective 18O labeling and mass spectrometry.

S. Gaskell, J. Barber, Waleed M. Alghamdi, 2012, Analytical chemistry.

Quantification of the proteins of the bacterial ribosome using QconCAT technology.

S. Gaskell, K. Carroll, Zubida M. Al-Majdoub, 2014, Journal of proteome research.

Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

K. Lea, J. Schageman, A. Rostami-Hodjegan, 2020, Clinical pharmacology and therapeutics.

Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis

Jill Barber, Amin Rostami-Hodjegan, Brahim Achour, 2014, Drug Metabolism and Disposition.

Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

A. Rostami-Hodjegan, B. Achour, J. Barber, 2011, Drug Metabolism and Disposition.

Proteome Profiles of Outer Membrane Vesicles and Extracellular Matrix of Pseudomonas aeruginosa Biofilms.

J. Dutcher, S. Schooling, Narciso Couto, 2015, Journal of proteome research.

Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2021, Molecular pharmaceutics.

Conformational analysis of the erythromycin analogues azithromycin and clarithromycin in aqueous solution and bound to bacterial ribosomes

R. Brennan, A. Awan, J. Barber, 1995 .

Selected Derivatives of Erythromycin B-In Silico and Anti-Malarial Studies

S. Freeman, J. Barber, B. Arsić, 2021, Materials.

Theoretical and experimental investigation on clarithromycin, erythromycin A and azithromycin and descladinosyl derivatives of clarithromycin and azithromycin with 3-O substitution as anti-bacterial agents

R. Brennan, A. Awan, A. McBain, 2014 .

Recycling of polyketides by fungi: the degradation of citrinin by Penicillium citrinum

T. Howard, G. Tebb, J. Barber, 1988, Applied Microbiology and Biotechnology.

The use of sodium [2-2H3,1,2-13C2]acetate in determining the biosynthetic origins of hydrogen atoms in fungal metabolites: the biosynthesis of citrinin by Penicillium citrinum.

T. Howard, J. Barber, A. C. Chapman, 1987, The Journal of antibiotics.

Erythromycin B: conformational analysis and antibacterial activity

D. Allison, M. Mordi, J. Barber, 2011 .

The conformations of the macrolide antibiotics erythromycin A, azithromycin and clarithromycin in aqueous solution: a 1H NMR study

R. Brennan, A. Awan, J. Barber, 2000 .

Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B.

G. Morris, D. Allison, J. Barber, 2016, Organic & biomolecular chemistry.

Pediatric erythromycins: a comparison of the properties of erythromycins A and B 2'-ethyl succinates.

P. A. Gorry, G. Morris, J. Barber, 2006, Journal of medicinal chemistry.

Design, synthesis, and evaluation of stable and taste-free erythromycin proprodrugs.

G. Morris, J. Barber, Pranab K. Bhadra, 2005, Journal of medicinal chemistry.

Acid-catalyzed degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy.

G. Morris, M. Mordi, J. Barber, 2000, Journal of medicinal chemistry.

Protium as a tracer in polyketide biosynthesis: incorporation of 13CH313CO2H into citrinin produced on a medium based on D2O

J. Staunton, J. Barber, 1979 .

Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics

A. Rostami-Hodjegan, J. Barber, N. Alizai, 2018, Expert opinion on drug metabolism & toxicology.

Improved methods of cultivation and production of deuteriated proteins from E. coli strains grown on fully deuteriated minimal medium.

D. Brockwell, P. Gilbert, O. Paliy, 2003, Journal of applied microbiology.

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Jill Barber, Bhagwat Prasad, Amin Rostami-Hodjegan, 2019, Clinical pharmacology and therapeutics.

Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro–in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2015, Expert opinion on drug metabolism & toxicology.

Choice of LC-MS Methods for the Absolute Quantification of Drug-Metabolizing Enzymes and Transporters in Human Tissue: a Comparative Cost Analysis

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2015, The AAPS Journal.

Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics

A. Rostami-Hodjegan, B. Achour, M. Russell, 2014, Drug Metabolism and Disposition.

Quantitative Proteomic Map of Enzymes and Transporters in the Human Kidney: Stepping Closer to Mechanistic Kidney Models to Define Local Kinetics

A. Galetin, A. Rostami-Hodjegan, B. Achour, 2021, Clinical pharmacology and therapeutics.

Tautomeric recognition of erythromycin a by ribosomes: A 1H nuclear magnetic resonance study

J. I. Gyi, J. Barber, D. Pye, 1990 .

Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2023, Frontiers in Oncology.

Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects

S. Peters, A. Rostami-Hodjegan, B. Achour, 2021, British journal of clinical pharmacology.

Proteomic quantification of perturbation to pharmacokinetic target proteins in liver disease.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Journal of Proteomics.

A family of QconCATs (Quantification conCATemers) for the quantification of human pharmacological target proteins.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Journal of proteomics.

Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2020, Clinical pharmacology and therapeutics.

Toward Systems-Informed Models for Biologics Disposition: Covariates of the Abundance of the Neonatal Fc Receptor (FcRn) in Human Tissues and Implications for Pharmacokinetic Modelling.

A. Rostami-Hodjegan, B. Achour, Narciso Couto, 2023, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters.

A. Rostami-Hodjegan, B. Achour, M. Russell, 2013, Journal of proteome research.

Proteomic characterisation of drug metabolising enzymes and drug transporters in pig liver

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Protein expression of various hepatic uridine 5′‐diphosphate glucuronosyltransferase (UGT) enzymes and their inter‐correlations: a meta‐analysis

A. Rostami-Hodjegan, B. Achour, J. Barber, 2014, Biopharmaceutics & drug disposition.

Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics

A. Rostami-Hodjegan, J. Barber, Yasmine Elmorsi, 2016, Drug Metabolism and Disposition.

Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease

M. Taha, H. Aojula, I. Alsalahat, 2021, Biochemistry and biophysics reports.

Full assignments of the 1H and 13C NMR spectra of the antibiotic kirromycin (mocimycin)

L. Lian, T. Howard, G. Tebb, 1989 .

Ten years of QconCATs: Application of multiplexed quantification to small medically relevant proteomes

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2015 .

Studies of the interaction of a meta-hydroxy analogue of hoechst 33258 with DNA by melting temperature, footprinting and high-resolution 1H NMR spectroscopy

K. Douglas, J. Parkinson, J. Barber, 1992 .

Adaptastat--a new method for optimising of bacterial growth conditions in continuous culture: Interactive substrate limitation based on dissolved oxygen measurement.

Jill Barber, J. Barber, Kalju Vanatalu, 2006, Journal of microbiological methods.

Choice of LC-MS Methods for the Absolute Quantification of Drug-Metabolizing Enzymes and Transporters in Human Tissue: a Comparative Cost Analysis

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2015, The AAPS Journal.

Label-Free but Still Constrained: Assessment of Global Proteomic Strategies for the Quantification of Hepatic Enzymes and Transporters

N. Couto, A. Rostami-Hodjegan, B. Achour, 2022, Drug Metabolism and Disposition.

Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2021, Drug Metabolism and Disposition.

Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity

T. Goosen, A. Rostami-Hodjegan, B. Achour, 2018, Drug Metabolism and Disposition.

The activities of Achromobacter lysyl endopeptidase and Lysobacter lysyl endoproteinase as digestive enzymes for quantitative proteomics.

B. Achour, J. Barber, 2013, Rapid communications in mass spectrometry : RCM.

The biosynthesis of fungal metabolites: sclerin, a plant growth hormone from Sclerotinia sclerotiorum

M. Garson, J. Staunton, J. Barber, 1981 .

Nuclear magnetic resonance studies on the mode of action of erythromycin A.

J. I. Gyi, J. Barber, 1991, Biochemical Society transactions.

Isomerization of erythromycin a in deuterium oxide and [2H6] dimethyl sulphoxide solutions: a 1H and 13C NMR study

G. Morris, J. I. Gyi, J. Barber, 1990 .

Physicochemical consequences of the perdeuteriation of glutathione S‐transferase from S. japonicum

S. Gaskell, D. Brockwell, D. Attwood, 2001, Protein Science.

Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

A. Rostami-Hodjegan, J. Barber, Brahim Achour, 2011, Drug Metabolism And Disposition.

Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

T. Goosen, A. Rostami-Hodjegan, J. Barber, 2017, Drug Metabolism and Disposition.

Effects of gentamicin on the proteomes of aerobic and oxygen-limited Escherichia coli.

S. Gaskell, Zubida M. Al-Majdoub, J. Barber, 2013, Journal of medicinal chemistry.

Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis

A. Rostami-Hodjegan, J. Barber, Brahim Achour, 2014, Drug Metabolism and Disposition.

A. Rostami-Hodjegan, Hajar Al Feteisi, J. Barber, 2015, Expert opinion on drug metabolism & toxicology.

Sodium [1,2‐13C2, 2H3]acetate

T. Howard, J. Barber, James Tearle, 1987 .

The X-ray crystal structures of perdeuteriated and protiated enzyme elongation factor Tu are very similar

J. Helliwell, D. Brockwell, J. Raftery, 1998 .

Examining Physiologically Based Pharmacokinetic Model Assumptions for Cross-Tissue Similarity of Activity per Unit of Enzyme: The Case Example of Uridine 5′-Diphosphate Glucuronosyltransferase

A. Rostami-Hodjegan, Zubida M. Al-Majdoub, J. Barber, 2022, Drug Metabolism And Disposition.