Timothy H. Pruess

发表

Synthesis and applications of polyamine amino acid residues: improving the bioactivity of an analgesic neuropeptide, neurotensin.

G. Bulaj, H. White, Liuyin Zhang, 2009, Journal of medicinal chemistry.

Introduction of lipidization–cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities

E. Scholl, G. Bulaj, H. White, 2010, Journal of peptide science : an official publication of the European Peptide Society.

Efficacy of mGlu2‐positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures

H. Lavreysen, R. Twyman, H. White, 2017, Epilepsia.

Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.

E. Scholl, G. Bulaj, H. White, 2008, Journal of medicinal chemistry.

Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.

G. Bulaj, H. White, Liuyin Zhang, 2009, Journal of medicinal chemistry.

Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.

E. Scholl, G. Bulaj, H. White, 2010, Journal of medicinal chemistry.

A Role of SCN9A in Human Epilepsies, As a Cause of Febrile Seizures and As a Potential Modifier of Dravet Syndrome

M. Leppert, M. Dixon, A. Peiffer, 2009, PLoS genetics.

Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs

K. Thomson, K. Wilcox, Misty D. Smith, 2020, Experimental Neurology.

Generating Orally Active Galanin Analogues with Analgesic Activities

G. Bulaj, H. White, Timothy H. Pruess, 2012, ChemMedChem.

Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model

K. Wilcox, M. Barker-Haliski, H. White, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain

K. Wilcox, Timothy H. Pruess, K. White, 2017, Neurochemical Research.

Acute treatment with minocycline, but not valproic acid, improves long‐term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy

K. Wilcox, M. Barker-Haliski, H. White, 2016, Epilepsia.

Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy

K. Wilcox, Zhenmei Lu, M. Barker-Haliski, 2017, Neurochemical Research.

Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models

E. Scholl, G. Bulaj, H. White, 2009, Neurotherapeutics.

Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions

K. Wilcox, C. Pappas, Nanda A. Singh, 2009, Epilepsia.

Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain

K. Wilcox, Timothy H. Pruess, K. White, 2017, Neurochemical Research.