C. Gieffers

发表

Mitotic regulation of the human anaphase‐promoting complex by phosphorylation

Karl Mechtler, Franz Herzog, Jan-Michael Peters, 2003, The EMBO journal.

Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint

Tim Hunt, Jan-Michael Peters, T. Hunt, 2001, The Journal of cell biology.

HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality

D. M. Richards, Matthias Schröder, C. Merz, 2019, Journal of Immunotherapy for Cancer.

A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity

D. M. Richards, C. Merz, C. Gieffers, 2018, Front. Oncol..

Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

Jan-Michael Peters, Markus Hengstschläger, J. Peters, 1998, Current Biology.

Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex

R. Huber, J. Peters, H. Vodermaier, 2001, Nature Structural Biology.

Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms.

C. Ungermann, P. Heimann, C. Gieffers, 1997, Experimental cell research.

Yes and PI3K bind CD95 to signal invasion of glioblastoma.

I. Sancho-Martinez, H. Sültmann, A. von Deimling, 2008, Cancer cell.

Characterization of the DOC1/APC10 Subunit of the Yeast and the Human Anaphase-promoting Complex*

Alexandre V. Podtelejnikov, Kim Nasmyth, Matthias Mann, 1999, The Journal of Biological Chemistry.

CMAR_A_216675 8095..8100

C. Gieffers, A. Krendyukov, 2019 .

Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro

P. Angel, C. Merz, C. Gieffers, 2015, Anti-cancer drugs.

Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase.

C. Gieffers, F. Korioth, J. Frey, 1994, Gene.

Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment

G. Maul, C. Gieffers, F. Korioth, 1995, The Journal of cell biology.

Concepts for agonistic targeting of CD40 in immuno-oncology

D. M. Richards, C. Merz, C. Gieffers, 2019, Human vaccines & immunotherapeutics.

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

C. Wirtz, A. Martin-Villalba, Á. Mateos, 2016, Cell Death and Disease.

Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.

J. Peters, K. Helin, E. L. Denchi, 2000, Genes & development.

Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma

A. von Deimling, U. Haberkorn, J. Debus, 2018, Molecular Cancer Research.

fundiInhibition of CD95/CD95L Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma

U. Haberkorn, A. Abdollahi, A. Deimling, 2018 .

The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.

R. Sprengel, I. Sancho-Martinez, N. Gretz, 2009, Cell stem cell.

Correction: CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

C. Wirtz, A. Martin-Villalba, Á. Mateos, 2020, Cell Death & Disease.

APG350 Induces Superior Clustering of TRAIL Receptors and Shows Therapeutic Antitumor Efficacy Independent of Cross-Linking via Fcγ Receptors

S. Fulda, P. Hohenberger, B. Abhari, 2013, Molecular Cancer Therapeutics.

In vitro reconstitution of recombinant lamin A and a lamin A mutant lacking the carboxy-terminal tail.

G. Krohne, C. Gieffers, 1991, European journal of cell biology.

Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons.

J. Peters, C. Dotti, C. Gieffers, 1999, Proceedings of the National Academy of Sciences of the United States of America.

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma

A. Trumpp, I. Sancho-Martinez, W. Weichert, 2015, Cell Death and Differentiation.

Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase

I. Sumara, J. Peters, C. Gieffers, 2000, The Journal of cell biology.

Cullins and cell cycle control

J. Peters, A. Schleiffer, C. Gieffers, 2000, Protoplasma.

The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells

H. Kalthoff, C. Röcken, J. Egberts, 2018, Cell Death & Disease.

TPR Subunits of the Anaphase-Promoting Complex Mediate Binding to the Activator Protein CDH1

Sebastian Maurer-Stroh, Frank Eisenhaber, Jan-Michael Peters, 2003, Current Biology.

Cell cycle – and cell growth – regulated proteolysis of mammalian CDC 6 is dependent on APC – CDH 1

J. Peters, K. Helin, E. L. Denchi, 2000 .

Asunercept as an innovative therapeutic approach for recurrent glioblastoma and other malignancies

C. Gieffers, A. Krendyukov, 2019, Cancer management and research.

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.

M. Mann, A. Podtelejnikov, J. Peters, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Three-dimensional structure of the anaphase-promoting complex.

J. Peters, H. Stark, P. Dube, 2001, Molecular cell.

CD95L and Anti-Tumor Immune Response: Current Understanding and New Evidence

D. M. Richards, C. Merz, C. Gieffers, 2021, Cancer management and research.

The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell–mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells

D. M. Richards, C. Merz, C. Gieffers, 2018, Journal of immunotherapy.

Three-dimensional structure of the human anaphase-promoting complex

J. Peters, P. Dube, C. Gieffers, 2002 .

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

Dietmar Riedel, Bjoern Sander, Franz Herzog, 2005, Molecular cell.

Abstracts from the 4th ImmunoTherapy of Cancer Conference

R. Rees, F. Regnier, A. Trautmann, 2017, Journal of Immunotherapy for Cancer.

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy

T. Illidge, Matthias Schröder, C. Merz, 2023, Frontiers in Immunology.

The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells

H. Kalthoff, C. Röcken, S. Boretius, 2018, Cell Death & Disease.

Receptor binding of osteoblast-specific factor 1 (OSF-1/HB-GAM) to human osteosarcoma cells promotes cell attachment.

J. Frey, C. Gieffers, T. Matsuishi, 1993, European journal of cell biology.