Xun Xu

Li Su, Xun Xu, Yi Lu, 2013, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

Fenoﬁbrate suppresses cellular metabolic memory of high glucose in diabetic retinopathy via a sirtuin 1-dependent signalling pathway.

N. Wang, Xun Xu, Q. Gu, 2015, Molecular medicine reports.

A randomised, parallel-group comparison study of diquafosol ophthalmic solution in patients with dry eye in China and Singapore

L. Tong, Xinghuai Sun, Zhi-zhong Ma, 2015, British Journal of Ophthalmology.

A case of anti-VEGF therapy application in Takayasu arteries with retinopathy

Feng’e Chen, T. Qian, Xun Xu, 2020, American journal of ophthalmology case reports.

H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-κB signal pathway.

Lili Wang, Qiao Sun, Yi Xu, 2014, Biochemical pharmacology.

H-RN, a peptide derived from hepatocyte growth factor, inhibits corneal neovascularization by inducing endothelial apoptosis and arresting the cell cycle

Li Su, Ye Sun, Yi Xu, 2013, BMC Cell Biology.

The role of N‐glycosylation in high glucose‐induced upregulation of intercellular adhesion molecule‐1 on bovine retinal endothelial cells

Xun Xu, Haiyun Liu, W. Ye, 2007, Acta ophthalmologica.

Analysis and quality control of carbohydrates in therapeutic proteins with fluorescence HPLC.

Xun Xu, Kun Liu, Zhigang Wu, 2016, Biochemical and biophysical research communications.

Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial ROS pathway mediated by PGC-1 Running Title: Statins improves diabetic retinopathy by PGC-1/ROS/PARP

B. Ke, Xun Xu, Peiyu Li, 2010 .

KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

Xiaolu Yang, Xun Xu, Kun Liu, 2019, Journal of Neuroinflammation.

Exogenous advanced glycosylation end products induce diabetes-like vascular dysfunction in normal rats: a factor in diabetic retinopathy

Xun Xu, Dawei Luo, Jianfeng Zhu, 2002, Graefe's Archive for Clinical and Experimental Ophthalmology.

Deacetylation of MnSOD by PARP-regulated SIRT3 protects retinal capillary endothelial cells from hyperglycemia-induced damage.

Xun Xu, Q. Gu, Zhi Zheng, 2016, Biochemical and biophysical research communications.

Inhibition of high glucose-induced apoptosis by uncoupling protein 2 in human umbilical vein endothelial cells.

Ying He, Ning Wang, Xun Xu, 2014, International journal of molecular medicine.

Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy.

P. Ho, Jianfeng Wu, H. Bi, 2006, Experimental eye research.

Interactions between Endostatin and Vascular Endothelial Growth Factor (VEGF) and Inhibition of Choroidal Neovascularization

C. Fan, S. Song, Xun Xu, 2007, International Journal of Molecular Sciences.

Epigallocatechin-3-gallate stimulates autophagy and reduces apoptosis levels in retinal Müller cells under high-glucose conditions.

Xiaodong Sun, Xun Xu, Manhui Zhu, 2019, Experimental cell research.

The effects of aminoguanidine on retinopathy in STZ-induced diabetic rats.

Xun Xu, Dawei Luo, Ying Fan, 2012, Bioorganic & medicinal chemistry letters.

PAPep Inhibits Secretion of Poly(I:C)-Induced Inflammatory Cytokines and ICAM-1 Expression in Corneal Fibroblasts by Suppressing the NF-κB/p38 Pathway.

Xiaolu Yang, Xun Xu, Q. Gu, 2018, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

Peptide GC31 inhibits chemokines and ICAM‐1 expression in corneal fibroblasts exposed to LPS or poly(I:C) by blocking the NF‐&kgr;B and MAPK pathways

Xun Xu, Q. Gu, Kun Liu, 2017, Experimental eye research.

PAPep, a small peptide derived from human pancreatitis-associated protein, attenuates corneal inflammation in vivo and in vitro through the IKKα/β/IκBα/NF-κB signaling pathway.

Xiaolu Yang, Xun Xu, Q. Gu, 2015, Pharmacological research.

Influence of Lactic Acid on Differential Expression of Vascular Endothelial Growth Factor and Pigment Epithelium-derived Factor in Explants of Rat Retina

Xun Xu, Jibo Zhou, Dongqing Zhu, 2012, Current eye research.

Safety and efficacy of conbercept in neovascular age-related macular degeneration: results from a 12-month randomized phase 2 study: AURORA study.

Xiaoling Liu, Shibo Tang, Xiaoxin Li, 2014, Ophthalmology.

Anti‐inflammatory effects of a synthetic peptide derived from pigment epithelium‐derived factor on H2O2‐induced corneal injury in vitro

Xun Xu, Yang Lili, J. Ji, 2014, Chinese Medical Journal.

LY2109761, Transforming Growth Factor β Receptor Type I and Type II Dual Inhibitor, is a Novel Approach to Suppress Endothelial Mesenchymal Transformation in Human Corneal Endothelial Cells

B. Ke, Xun Xu, Kun Liu, 2018, Cellular Physiology and Biochemistry.

Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs

P. Zamore, G. Gao, Q. Su, 2017, Molecular therapy. Nucleic acids.

Perfluorocarbon Liquid: Its Application in Vitreoretinal Surgery and Related Ocular Inflammation

Li Su, Xun Xu, Qi Yu, 2014, BioMed research international.

Therapeutic effects of a novel PIGF-1 derived peptide, ZY-1, on corneal neovascularization in vitro and in vivo.

Xun Xu, J. Ai, Ying Zheng, 2016, Discovery medicine.

Perfluorocarbon Liquid : Its Application in Vitreoretinal Surgery and Related Ocular Inflammation

Li Su, Xun Xu, Qi Yu, 2015 .

Vitreous Substitutes: From Tamponade Effect to Intraocular Inflammation

M. Romano, Kenneth K. W. Li, Xun Xu, 2014, BioMed research international.

A novel peptide specifically binding to VEGF receptor suppresses angiogenesis in vitro and in vivo

Bifang He, Yuan Zhang, Jian Huang, 2017, Signal Transduction and Targeted Therapy.

The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells

Xun Xu, D. Qin, Guo-ming Zhang, 2015, Journal of diabetes research.

LncRNA TDRG1-Mediated Overexpression of VEGF Aggravated Retinal Microvascular Endothelial Cell Dysfunction in Diabetic Retinopathy

Feng’e Chen, T. Qian, Xun Xu, 2020, Frontiers in Pharmacology.

Involvement of ciliary neurotrophic factor in early diabetic retinal neuropathy in streptozotocin-induced diabetic rats

Yupeng Xu, B. Ke, Xun Xu, 2018, Eye.

Novel peptide derived from IGF‐2 displays anti‐angiogenic activity in vitro and inhibits retinal angiogenesis in a model of oxygen‐induced retinopathy

Qiao Sun, Xun Xu, Weijun Wang, 2020, Clinical & experimental ophthalmology.

Protective or Harmful: The Dual Roles of Autophagy in Diabetic Retinopathy

T. Qian, Xun Xu, Haiyan Wang, 2021, Frontiers in Medicine.

Neuroprotective effects of a novel peptide, FK18, under oxygen-glucose deprivation in SH-SY5Y cells and retinal ischemia in rats via the Akt pathway

Yupeng Xu, Xun Xu, Q. Gu, 2017, Neurochemistry International.

Activation of the TXNIP/NLRP3 inflammasome pathway contributes to inflammation in diabetic retinopathy: a novel inhibitory effect of minocycline

Qinghua Qiu, Xun Xu, H. Guan, 2017, Inflammation Research.

A novel peptide from human apolipoprotein(a) inhibits angiogenesis and tumor growth by targeting c‐Src phosphorylation in VEGF‐induced human umbilical endothelial cells

Hui Zhao, Jian Luo, Sung-Gook Cho, 2009, International journal of cancer.

A SiRNA Targeting Vascular Endothelial Growth Factor-A Inhibiting Experimental Corneal Neovascularization

Feng Wang, Xun Xu, Q. Gu, 2010, Current eye research.

A novel antiangiogenic peptide derived from hepatocyte growth factor inhibits neovascularization in vitro and in vivo

Hui Zhao, Ying Zheng, Qing Gu, 2010, Molecular vision.

Methanesulfonic acid sodium salt protects retina from acute light damage in mice.

Xun Xu, Q. Gu, Haiyan Wang, 2012, Chinese Medical Journal.

Sirtuin 1–Mediated Cellular Metabolic Memory of High Glucose Via the LKB1/AMPK/ROS Pathway and Therapeutic Effects of Metformin

Ying He, Xun Xu, Q. Gu, 2011, Diabetes.

KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

Xiaolu Yang, Xun Xu, Kun Liu, 2019, Journal of Neuroinflammation.

Implementation and first-year screening results of an ocular telehealth system for diabetic retinopathy in China

Haidong Zou, Xun Xu, Xun Xu, 2011, BMC health services research.

Comparison of the efficacy and safety of drug therapies for macular edema secondary to central retinal vein occlusion

T. Qian, Xun Xu, Mengya Zhao, 2018, BMJ Open.

Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation

Li Su, Xun Xu, Q. Gu, 2017, Journal of Translational Medicine.

A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced pro-angiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Müller cells.

Xiaodong Sun, Xun Xu, Xiaojuan Liu, 2020, Experimental eye research.

Involvement of RhoA/ROCK1 signaling pathway in hyperglycemia-induced microvascular endothelial dysfunction in diabetic retinopathy.

Xun Xu, Zhi Zheng, Wei Chen, 2014, International journal of clinical and experimental pathology.

Identification of Age-Related Macular Degeneration Related Genes by Applying Shortest Path Algorithm in Protein-Protein Interaction Network

Lei Chen, Yu-Dong Cai, Kai-Yan Feng, 2013, BioMed research international.

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

P. Lu, Fudong Yu, Xun Xu, 2021, Frontiers in Pharmacology.

Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: a pilot study

S. Zhong, Hui Jiang, Hemi Luan, 2013, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Effects of asymmetric dimethylarginine on bovine retinal capillary endothelial cell proliferation, reactive oxygen species production, permeability, intercellular adhesion molecule-1, and occludin expression

Xun Xu, Q. Gu, Zhi Zheng, 2011, Molecular vision.

Single cell RNA sequencing (scRNA-Seq) deciphering pathological alterations in streptozotocin-induced diabetic retinas.

Xun Xu, Qihuang Jin, Jing Hu, 2021, Experimental eye research.

Identification of genes related to proliferative diabetic retinopathy through RWR algorithm based on protein-protein interaction network.

Yan Suo, Jian Zhang, Min Liu, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF through a mitochondrial ROS pathway in vitro.

Xiaolu Yang, Hui Zhao, Xun Xu, 2010, Investigative ophthalmology & visual science.

Role of protein kinase C on the alteration of retinal endothelin-1 in streptozotocin-induced diabetic rats.

P. Ho, Xun Xu, Q. Gu, 2005, Experimental eye research.

MicroRNA‐93 inhibits inflammatory cytokine production in LPS‐stimulated murine macrophages by targeting IRAK4

Li Su, Xiaolu Yang, Lili Wang, 2014, FEBS letters.

Prodrug of epigallocatechin-3-gallate alleviates choroidal neovascularization via down-regulating HIF-1α/VEGF/VEGFR2 pathway and M1 type macrophage/microglia polarization.

Xiaodong Sun, Xun Xu, Yuanyuan Tu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Blood-retinal barrier breakdown induced by activation of protein kinase C via vascular endothelial growth factor in streptozotocin-induced diabetic rats

Qing Gu, Qi Zhu, Xun Xu, 2004, Current eye research.

PPARα regulates mobilization and homing of endothelial progenitor cells through the HIF-1α/SDF-1 pathway.

Jian-xing Ma, Xun Xu, Zhongxiao Wang, 2014, Investigative ophthalmology & visual science.

Retina PPAR a Regulates Mobilization and Homing of Endothelial Progenitor Cells Through the HIF-1 a / SDF-1 Pathway

Jian-xing Ma, Xun Xu, Zhongxiao Wang, 2014 .

SENP1-Mediated Desumoylation of DBC1 Inhibits Apoptosis Induced by High Glucose in Bovine Retinal Pericytes

Xun Xu, Q. Gu, Xiaoxiao Liu, 2016, Journal of ophthalmology.

Robust deep learning method for choroidal vessel segmentation on swept source optical coherence tomography images.

Xun Xu, Dagan Feng, Jinman Kim, 2019, Biomedical optics express.

Novel Peptide NT/K-CFY Derived from Kringle Structure of Neurotrypsin Inhibits Neovascularization

Yupeng Xu, Xun Xu, Q. Gu, 2021, Current eye research.

Insulin-Like Growth Factor Binding Protein-Related Protein 1 Inhibit Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy.

Hong Wang, T. Sun, Xun Xu, 2017, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

Two different treatment regimens of ranibizumab 0.5 mg for neovascular age‐related macular degeneration with or without polypoidal choroidal vasculopathy in Chinese patients: results from the Phase IV, randomized, DRAGON study

S. Wolf, Yanping Song, F. Dong, 2020, Acta ophthalmologica.

Nerve Growth Factor Helps Protect Retina in Experimental Retinal Detachment

Xiaodong Sun, P. Ho, Fenghua Wang, 2007, Ophthalmologica.

A Novel Small Peptide H-KI20 Inhibits Retinal Neovascularization Through the JNK/ATF2 Signaling Pathway

Xihui Gao, Yi Xu, Xun Xu, 2021, Investigative ophthalmology & visual science.

A light‐emitting diode (LED)‐based multispectral imaging system in evaluating retinal vein occlusion

Yupeng Xu, Yupeng Xu, Li Su, 2015, Lasers in surgery and medicine.

Nanoparticle-Mediated Expression of a Wnt Pathway Inhibitor Ameliorates Ocular Neovascularization

J. Chen, Jian-xing Ma, P. Tyagi, 2015, Arteriosclerosis, thrombosis, and vascular biology.

A cross‐sectional study of vitreous and serum high mobility group box‐1 levels in proliferative diabetic retinopathy

Feng’e Chen, Ning Wang, Xun Xu, 2019, Acta ophthalmologica.