S. Ofner

发表

AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization.

F. Gasparini, I. Vranesic, G. Bilbe, 2014, Bioorganic & medicinal chemistry.

Anti-Proteus activity of some South African medicinal plants : their potential for the prevention of rheumatoid arthritis

M. Fendt, S. Hintermann, D. Hoyer, 2013 .

A General Strategy for Targeting Drugs to Bone.

W. Jahnke, G. Bold, X. Pelle, 2015, Angewandte Chemie.

Discovery of Novel Allosteric Non‐Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding

W. Jahnke, G. Bold, T. Roddy, 2015, ChemMedChem.

6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists.

S. Urwyler, W. Froestl, K. Lingenhoehl, 2012, Bioorganic & medicinal chemistry letters.

N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1999, Bioorganic & medicinal chemistry letters.

5-Aminomethylquinoxaline-2,3-diones. Part II: N-aryl derivatives as novel NMDA/glycine and AMPA antagonists.

P. Acklin, Y. Auberson, M. Biollaz, 1998, Bioorganic & medicinal chemistry letters.

Kinetic properties of “dual” orexin receptor antagonists at OX1R and OX2R orexin receptors

M. Fendt, E. Briard, S. Hintermann, 2013, Front. Neurosci..

Distinct effects of IPSU and suvorexant on mouse sleep architecture

M. Fendt, S. Hintermann, D. Hoyer, 2013, Front. Neurosci..

Reaction of α-Lithioacetic Acid Esters with Succinic Anhydrides

F. Montforts, S. Ofner, 1979 .

Reaktion von α-Lithioessigsäureestern mit Bernsteinsäureanhydriden

F. Montforts, S. Ofner, 1979 .

The potency of the novel tachykinin receptor antagonist CGP49823 at rat and gerbil motoneurones in vitro.

R. H. Evans, M. Pozza, S. Ofner, 1998, European journal of pharmacology.

NKP608: a selective NK-1 receptor antagonist with anxiolytic-like effects in the social interaction and social exploration test in rats

S. Ofner, W. Schilling, A. Vassout, 2000, Regulatory Peptides.

A Synthetic Approach to the Isobacteriochlorin Macrocycle

F. Montforts, A. Eschenmoser, A. Battersby, 1979 .

5-Aminomethylquinoxaline-2,3-diones, Part III: Arylamide derivatives as highly potent and selective glycine-site NMDA receptor antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1998, Bioorganic & medicinal chemistry letters.

SAR of 2-benzyl-4-aminopiperidines: CGP 49823, an orally and centrally active non-peptide NK1 antagonist

S. Ofner, A. Vassout, S. Veenstra, 1996 .

SAR of 2-benzyl-4-aminopiperidines NK1 antagonists. Part 21. synthesis of CGP 49823

S. Ofner, C. Betschart, W. Schilling, 1996 .

CGP 49823, a novel NK1 receptor antagonist: Behavioural effects

S. Ofner, A. Vassout, C. Gentsch, 1994, Neuropeptides.

Pharmacological characterization of some selected 4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates and 3-hydroxyquinazoline-2,4-diones as (S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionic acid receptor antagonists.

K. Lingenhöhl, S. Ofner, Ombretta Lenzi, 2010, Chemical & pharmaceutical bulletin.

Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia.

M. Fendt, S. Hintermann, D. Hoyer, 2013, Journal of medicinal chemistry.

Evaluation of Potent Odorants in Cucumbers (Cucumis sativus) and Muskmelons (Cucumis melo) by Aroma Extract Dilution Analysis

P. Schieberle, W. Grosch, S. Ofner, 1990 .

A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.

J. Cryan, O. Pescott, P. Flor, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold*

N. Schmiedeberg, G. Fendrich, T. Troxler, 2015, The Journal of Biological Chemistry.

5‐Aminomethylquinoxaline‐2,3‐diones. Part 3. Arylamide Derivatives as Highly Potent and Selective Glycine‐Site NMDA Receptor Antagonists.

P. Acklin, Y. Auberson, M. Schmutz, 1998 .

Quinazolinedione sulfonamides: a novel class of competitive AMPA receptor antagonists with oral activity.

Y. Auberson, I. Vranesic, S. Urwyler, 2011, Bioorganic & medicinal chemistry letters.

Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior♦

M. Fendt, J. Cryan, I. Vranesic, 2014, The Journal of Biological Chemistry.

CGP 49823, a novel, non-peptidic NK-1 receptor antagonist: in vitro pharmacology

J. Heid, S. Ofner, L. Criscione, 1994, Neuropeptides.