B. Slütter

发表

The many faces of CD8+ T cells in atherosclerosis

J. Kuiper, J. van Duijn, B. Slütter, 2018, Current opinion in lipidology.

Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation.

Wim Jiskoot, W. Jiskoot, J. Bouwstra, 2011, Vaccine.

Hyaluronan molecular weight: effects on dissolution time of dissolving microneedles in the skin and on immunogenicity of antigen.

J. Bouwstra, C. O’Mahony, G. Kersten, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model

J. Drijfhout, J. Kuiper, I. Bot, 2019, Scientific Reports.

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

G. Vriend, L. Boon, L. Beckers, 2018, Journal of the American College of Cardiology.

Submicron Size Particles of a Murine Monoclonal Antibody Are More Immunogenic Than Soluble Oligomers or Micron Size Particles Upon Subcutaneous Administration in Mice.

Jared S. Bee, M. Schenerman, W. Jiskoot, 2018, Journal of pharmaceutical sciences.

Vaccines

W. Jiskoot, E. Mastrobattista, G. Kersten, 2019, Reactions Weekly.

CD8+ T-cells contribute to lesion stabilization in advanced atherosclerosis by limiting macrophage content and CD4+ T-cell responses

W. Jiskoot, J. Kuiper, I. Bot, 2018, Cardiovascular research.

Immune Responses in Context.

J. Kuiper, B. Slütter, 2019, Circulation.

A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine.

W. Hennink, W. Jiskoot, E. Mastrobattista, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Antigen-adjuvant nanoconjugates for nasal vaccination: an improvement over the use of nanoparticles?

W. Jiskoot, J. Bouwstra, C. Löwik, 2010, Molecular pharmaceutics.

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

C. Glass, T. Lönnberg, M. Mokry, 2020, Circulation research.

ArticleFlow Cytometry-Based Characterization of Mast Cells in Human AtherosclerosisEva Kritikou 1

P. Quax, J. Kuiper, I. Bot, 2019 .

Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

P. Quax, J. Kuiper, I. Bot, 2019, Cells.

BTLA stimulation protects against atherosclerosis by regulating follicular B cells.

J. Kuiper, I. Bot, H. Yagita, 2019, Cardiovascular research.

B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells

J. Kuiper, I. Bot, H. Yagita, 2019 .

Hypercholesterolemia Induces a Mast Cell–CD4+ T Cell Interaction in Atherosclerosis

P. Maffia, J. Kuiper, I. Bot, 2019, The Journal of Immunology.

PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity

W. van Eden, W. Jiskoot, C. Keijzer, 2011, PloS one.

Rational design of nasal vaccines

W. Jiskoot, B. Slütter, N. Hagenaars, 2008, Journal of drug targeting.

High-affinity antigen association to cationic liposomes via coiled coil-forming peptides induces a strong antigen-specific CD4+ T-cell response.

W. Jiskoot, A. Kros, B. Slütter, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Efficient induction of immune responses through intradermal vaccination with N-trimethyl chitosan containing antigen formulations.

Elly van Riet, Gideon F A Kersten, Wim Jiskoot, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Hepatitis B surface antigen nanoparticles coated with chitosan and trimethyl chitosan: Impact of formulation on physicochemical and immunological characteristics.

W. Jiskoot, Jean‐Pierre Amorij, G. Kersten, 2012, Vaccine.

Adjuvant effect of cationic liposomes and CpG depends on administration route.

W. Jiskoot, J. Bouwstra, B. Slütter, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination.

W. Hennink, W. Jiskoot, J. Bouwstra, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination.

W. Jiskoot, B. Slütter, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination.

W. Jiskoot, Y. Schneider, V. Préat, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Anionic 1,2‐distearoyl‐sn‐glycero‐3‐phosphoglycerol (DSPG) liposomes induce antigen‐specific regulatory T cells and prevent atherosclerosis in mice

W. Jiskoot, J. Kuiper, P. V. van Veelen, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen.

W. Hennink, W. Jiskoot, P. Soema, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Chapter 5 Efficient induction of immune responses through intradermal vaccination with TMC containing antigen formulations

W. Jiskoot, G. Kersten, B. Slütter, 2010 .

5 Nanoparticles differentially modulate the outcome of nasal vaccination by enhancing mucosal tolerance or inducing protective immunity

W. Jiskoot, C. Keijzer, F. Broere, 2011 .

CD8 1 T-cells contribute to lesion stabilization in advanced atherosclerosis by limiting macrophage content and CD4 1 T-cell responses

W. Jiskoot, J. Kuiper, I. Bot, 2019 .

Tolerogenic vaccines for the treatment of cardiovascular diseases

J. Kuiper, B. Slütter, F. L. Vigario, 2020, EBioMedicine.

NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice—Brief Report

J. Kuiper, I. Bot, J. van Duijn, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunity

J. Harty, S. Salek-Ardakani, S. Varga, 2017, Science Immunology.

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death

M. Daemen, C. Weber, H. Poelman, 2018, European heart journal.

PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity

W. Jiskoot, P. Soema, F. Ossendorp, 2016, Human vaccines & immunotherapeutics.

Instructing the instructor: tissue-resident T cells activate innate immunity.

J. Harty, B. Slütter, 2014, Cell host & microbe.

Chapter 7

W. Jiskoot, J. Bouwstra, B. Slütter, 2009 .

OP-CVRE190132 1..11

J. Kuiper, I. Bot, H. Yagita, 2019 .

Blockade of the BLT1-LTB4 axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr−/− mice

J. Kuiper, I. Bot, B. Slütter, 2022, Scientific Reports.

Sizing the optimal dimensions of a vaccine delivery system: a particulate matter

W. Jiskoot, B. Slütter, 2016, Expert opinion on drug delivery.

Development of PLGA nanoparticle loaded dissolving microneedles and comparison with hollow microneedles in intradermal vaccine delivery

W. Jiskoot, J. Bouwstra, C. O’Mahony, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators

B. Slütter, Ruža Frkanec, Ž. Jakopin, 2022, Journal of medicinal chemistry.

Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity

J. Plavec, I. Mlinarič-Raščan, S. Pajk, 2021, Journal of medicinal chemistry.

Modulation of immune responses using adjuvants to facilitate therapeutic vaccination

C. Rosano, E. Lavelle, D. Christensen, 2020, Immunological reviews.

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems.

Yvonne Perrie, Wim Jiskoot, W. Jiskoot, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

Koen van der Maaden, Alexander Kros, Wim Jiskoot, 2017, Pharmaceutical Research.

Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

W. Jiskoot, J. Bouwstra, P. Bomans, 2017, Pharmaceutical Research.

Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles

Abraham J. Koster, Roman I. Koning, Alexander Kros, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Lipid nanoparticle-based mRNA candidates elicit potent T cell responses.

A. Kros, B. Slütter, Oscar Escalona-Rayo, 2022, Biomaterials science.

Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus.

S. Kaech, J. Harty, B. Slütter, 2013, Immunity.

Mannosylated self‐peptide inhibits the development of experimental autoimmune encephalomyelitis via expansion of nonencephalitogenic T cells

J. Drijfhout, F. Koning, B. Slütter, 2008, Journal of leukocyte biology.

Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells

G. Pasterkamp, G. D. de Borst, J. Kuiper, 2023, Nature Cardiovascular Research.

Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines.

W. Jiskoot, J. Kuiper, J. van Duijn, 2016, Journal of controlled release : official journal of the Controlled Release Society.

2 Rational design of nasal vaccines

W. Jiskoot, B. Slütter, N. Hagenaars, 2011 .

Towards tailored vaccine delivery: needs, challenges and perspectives.

W. Hinrichs, W. Jiskoot, J. Bouwstra, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells

T. Hankemeier, H. Chi, A. Harms, 2020, Cardiovascular research.

Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates

Alexandria K. D’Souza, B. Gibson, J. Harty, 2017, mBio.

Adjuvanted, antigen loaded N-trimethyl chitosan nanoparticles for nasal and intradermal vaccination: adjuvant- and site-dependent immunogenicity in mice.

W. Jiskoot, J. Bouwstra, B. Slütter, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Tc17 CD8+ T cells accumulate in murine atherosclerotic lesions, but do not contribute to early atherosclerosis development

W. Jiskoot, J. Kuiper, I. Bot, 2020, Cardiovascular research.

Cutting Edge: Rapid Boosting of Cross-Reactive Memory CD8 T Cells Broadens the Protective Capacity of the Flumist Vaccine

J. Harty, B. Slütter, P. Lauer, 2013, The Journal of Immunology.

Flumist Vaccine Broadens the Protective Capacity of the Cross-Reactive Memory CD 8 T Cells Cutting Edge : Rapid Boosting of

J. Harty, B. Slütter, P. Lauer, 2013 .

Cationic liposomes bearing Bet v 1 by coiled coil-formation are hypo-allergenic and induce strong immunogenicity in mice

R. Van Ree, W. Jiskoot, A. Kros, 2023, Frontiers in Allergy.

Gold nanoparticles decorated with ovalbumin-derived epitopes: effect of shape and size on T-cell immune responses

A. Boyle, A. Kros, B. Slütter, 2022, RSC advances.

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.

Ivo Que, Joke Bouwstra, Patrick Augustijns, 2010, Vaccine.

Elastin-like polypeptide-based micelles as a promising platform in nanomedicine.

W. Jiskoot, A. Kros, B. Slütter, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation

K. Campbell, Y. Hara, J. Harty, 2019, Proceedings of the National Academy of Sciences.

Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques

A. Boyle, W. Jiskoot, J. Bouwstra, 2020, Advanced healthcare materials.

Uptake Kinetics of Liposomal Formulations of Differing Charge Influences Development of In Vivo Dendritic Cell Immunotherapy.

W. Jiskoot, T. Geijtenbeek, Y. van Kooyk, 2022, Journal of pharmaceutical sciences.

Atomic force microscopy measurements of anionic liposomes reveal the effect of liposomal rigidity on antigen-specific regulatory T cell responses.

W. Jiskoot, J. Kuiper, J. van Duijn, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine.

W. Jiskoot, E. Mastrobattista, J. Heldens, 2010, Journal of controlled release : official journal of the Controlled Release Society.

RESULTS Single-Cell RNA Sequencing Identifies 14 Distinct Cell Populations in Human Atherosclerotic Plaques

C. Glass, T. Lönnberg, M. Mokry, 2022 .

Liposomes loaded with vitamin D3 induce regulatory circuits in human dendritic cells

T. Geijtenbeek, E. D. de Jong, B. Slütter, 2023, Frontiers in Immunology.

Monoclonal Antibody Dimers Induced by Low pH, Heat, or Light Exposure Are Not Immunogenic Upon Subcutaneous Administration in a Mouse Model.

Jared S. Bee, M. Schenerman, W. Jiskoot, 2019, Journal of pharmaceutical sciences.

THE USE OF A STAGGERED HERRINGBONE MICROMIXER FOR THE PREPARATION OF RIGID LIPOSOMAL FORMULATIONS ALLOWS EFFICIENT ENCAPSULATION OF ANTIGEN AND ADJUVANT.

W. Jiskoot, J. Bouwstra, A. Kros, 2022, Journal of pharmaceutical sciences.

In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy.

A. Kros, B. Slütter, Oscar Escalona-Rayo, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

CD39 identifies a microenvironment-specific anti-inflammatory CD8+ T-cell population in atherosclerotic lesions.

W. Jiskoot, J. Kuiper, I. Bot, 2019, Atherosclerosis.

Tuning the Cross-Linking Density and Cross-Linker in Core Cross-Linked Polymeric Micelles and Its Effects on the Particle Stability in Human Blood Plasma and Mice

P. Besenius, R. Zentel, K. Koynov, 2023, Biomacromolecules.

Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation

I. Bot, H. Björkbacka, D. Liberg, 2024, Cardiovascular research.

Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus.

S. Kaech, J. Harty, B. Slütter, 2013, Immunity.