Xin Chen

发表

Differential response of murine CD4+CD25+ and CD4+CD25– T cells to dexamethasone‐induced cell death

Xin Chen, Takaya Murakami, J. Oppenheim, 2004, European journal of immunology.

Cellular pharmacology studies of shikonin derivatives

Xin Chen, J. Oppenheim, Lu Yang, 2002, Phytotherapy research : PTR.

Splenic CD19-CD35+B220+ cells function as an inducer of follicular dendritic cell network formation.

A. Sakamoto, K. Hase, H. Ohno, 2007, Blood.

Glucocorticoid amplifies IL‐2‐dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE

J. Ortaldo, Xin Chen, J. Oppenheim, 2006, European journal of immunology.

BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25− responder T cells than C57BL/6 mice

Xin Chen, J. Oppenheim, O. Howard, 2005, Journal of leukocyte biology.

IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells

Xueqiang Wu, Xin Chen, J. Oppenheim, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Co‐expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood

R. Wiltrout, Xin Chen, J. Oppenheim, 2010, European journal of immunology.

Effective Chemoimmunotherapy with Anti-TGFβ Antibody and Cyclophosphamide in a Mouse Model of Breast Cancer

J. Weiss, L. Wakefield, Yuan Yang, 2014, PloS one.

IKKa is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells

Xueqiang Wu, Xin Chen, J. Oppenheim, 2020 .

CD4+CD25+ Treg derived from hepatocellular carcinoma mice inhibits tumor immunity.

Xin Chen, Zhi-ming Huang, Yong Du, 2012, Immunology letters.

Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3− Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells

A. Hurwitz, Xin Chen, J. Oppenheim, 2010, The Journal of Immunology.

TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells.

Xin Chen, J. Oppenheim, 2010, Current directions in autoimmunity.

Characterization of MT-2 cells as a human regulatory T cell-like cell line

Yitao Wang, Xueqiang Wu, Xin Chen, 2014, Cellular and Molecular Immunology.

Comment on “Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis”

Xin Chen, J. Oppenheim, 2011, The Journal of Immunology.

The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4+ FoxP3+ regulatory T cells

Xin Chen, J. Oppenheim, 2011, Immunology.

Tannic Acid Is an Inhibitor of CXCL12 (SDF-1α)/CXCR4 with Antiangiogenic Activity

R. Salcedo, O. Chertov, J. Beutler, 2003 .

Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants.

R. D. Mellon, Xin Chen, J. Oppenheim, 2002, Biochemical pharmacology.

Development of regulatory T cells requires IL-7R (cid:1) stimulation by IL-7 or TSLP

W. Leonard, W. Li, R. Mazzucchelli, 2008 .

Increased frequency of Foxp3+ regulatory T cells in mice with hepatocellular carcinoma.

Xin Chen, X. Ye, Zhi-ming Huang, 2012, Asian Pacific journal of cancer prevention : APJCP.

Effects of IL-7 and dexamethasone: induction of CD25, the high affinity IL-2 receptor, on human CD4+ cells.

N. Hassanein, I. Chung, Xin Chen, 2004, Cellular immunology.

Interaction of TNF with TNF Receptor Type 2 Promotes Expansion and Function of Mouse CD4+CD25+ T Regulatory Cells1

D. Männel, Xin Chen, J. Oppenheim, 2007, The Journal of Immunology.

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

M. Netea, Xueqiang Wu, Xin Chen, 2013, The Journal of Immunology.

Chemokines and chemokine receptors as novel therapeutic targets in rheumatoid arthritis (RA): inhibitory effects of traditional Chinese medicinal components.

Xin Chen, J. Oppenheim, O. Howard, 2004, Cellular & molecular immunology.

Progranulin promotes tumour necrosis factor‐induced proliferation of suppressive mouse CD4+ Foxp3+ regulatory T cells

T. Shi, Hai-tao Xiao, Xin Chen, 2014, Immunology.

The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant.

M. Bustin, P. Tewary, Xin Chen, 2014, Cancer research.

Effects of Shuanghuanglian and Qingkailing, two multi-components of traditional Chinese medicinal preparations, on human leukocyte function.

Xin Chen, J. Oppenheim, O. Howard, 2002, Life sciences.

Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells.

E. Hurt, W. Farrar, Joon-Young Kim, 2007, Biochemical and biophysical research communications.

Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells

J. Ortaldo, N. Carbonetti, Xin Chen, 2006, European journal of immunology.

Suppressive activity of human regulatory T cells is maintained in the presence of TNF

B. Salomon, M. Miyara, Xin Chen, 2016, Nature Medicine.

to migrate CXCR3 and CXCR5 expressing lymphocytes and immature dendritic cells Autoantigens signal through chemokine receptors: uveitis antigens induce

S. Su, P. Plotz, R. Caspi, 2013 .

Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.

S. Su, P. Plotz, R. Caspi, 2005, Blood.

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells1

D. Männel, Xin Chen, J. Oppenheim, 2008, The Journal of Immunology.

Expression Maturation : Correlation with Receptor fMLP and C 5 a Upon Dendritic Cell Differential Regulation of Responsiveness to Howard and

S. Stoll, Xin Chen, J. Oppenheim, 2000 .

Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking.

Xin Chen, Takaya Murakami, J. Oppenheim, 2005, Blood.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014, The Journal of Immunology.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/aCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Cell Death during IL-2/ Microenvironment Undergo Fas-Dependent Suppressor Cells in the Tumor Regulatory T Cells and Myeloid-Derived

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment

J. Weiss, J. Stauffer, T. Back, 2009, Proceedings of the National Academy of Sciences.

Applicability to Tumor-Infiltrating T T Regulatory Cells : + FoxP 3 + CD 25 + CD 4 a Maximally Suppressive Subset of Mouse Cutting Edge : Expression of TNFR 2 Defines

D. Männel, Xin Chen, J. Oppenheim, 2008 .

T Regulatory Cells + CD 25 + Mouse CD 4 2 Promotes Expansion and Function of Interaction of TNF with TNF Receptor Type

D. Männel, Xin Chen, J. Oppenheim, 2007 .

Shikonin, a Component of Chinese Herbal Medicine, Inhibits Chemokine Receptor Function and Suppresses Human Immunodeficiency Virus Type 1

R. Buckheit, Xin Chen, J. Oppenheim, 2003, Antimicrobial Agents and Chemotherapy.

Triptolide Attenuates Endotoxin- and Staphylococcal Exotoxin-Induced T-Cell Proliferation and Production of Cytokines and Chemokines

H. Young, Xin Chen, O. Howard, 2005, Immunopharmacology and immunotoxicology.

Dendritic cells as a pharmacological target of traditional Chinese medicine.

Xin Chen, J. Oppenheim, Lu Yang, 2006, Cellular & molecular immunology.

Differential Regulation of Responsiveness to fMLP and C5a Upon Dendritic Cell Maturation: Correlation with Receptor Expression1 2

S. Stoll, Xin Chen, J. Oppenheim, 2000, The Journal of Immunology.

Tumor-derived CD4+CD25+ Tregs inhibit the maturation and antigen-presenting function of dendritic cells.

Wei Wu, Xin Chen, Zhi-ming Huang, 2015, Asian Pacific journal of cancer prevention : APJCP.

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.

W. Leonard, W. Li, R. Mazzucchelli, 2008, Blood.

Tumor-derived CD4+CD25+regulatory T cells inhibit dendritic cells function by CTLA-4.

Xin Chen, Zhiming Huang, Yong Du, 2017, Pathology, research and practice.

Th17 cells and Tregs: unlikely allies

Xin Chen, J. Oppenheim, 2014, Journal of leukocyte biology.

In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo.

Xin Chen, J. Oppenheim, O. Howard, 2014, Cytokine.

Pertussis Toxin by Inducing IL-6 Promotes the Generation of IL-17-Producing CD4 Cells1

Xin Chen, J. Oppenheim, O. Howard, 2007, The Journal of Immunology.

Pertussis Toxin by Inducing IL-6 Promotes

Xin Chen, J. Oppenheim, O. Howard, 2007 .

Cellsthe Generation of IL-17-Producing CD 4 Pertussis Toxin by Inducing IL-6 Promotes

Xin Chen, J. Oppenheim, O. Howard, 2007 .

CD4+CD25+ regulatory T cells in tumor immunity.

Yan Qian, Xin Chen, Zhi-ming Huang, 2016, International immunopharmacology.

Resolving the identity myth: key markers of functional CD4+FoxP3+ regulatory T cells.

Xin Chen, Xin Chen, J. Oppenheim, 2011, International immunopharmacology.

Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells.

G. de la Rosa, Xin Chen, O. Howard, 2007, International immunopharmacology.

Contrasting effects of TNF and anti‐TNF on the activation of effector T cells and regulatory T cells in autoimmunity

Xin Chen, J. Oppenheim, 2011, FEBS letters.

Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer.

Huan Gui, Xin Chen, De Yang, 2023, Biochemical and biophysical research communications.

TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4^+Foxp3^+ regulatory T cells

Md. Sahidul Islam, C. Chou, D. Faustman, 2022, Cellular Oncology.

Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors

Xin Chen, J. Oppenheim, De Yang, 2017, Scientific Reports.

Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer

Xin Chen, J. Oppenheim, 2017, Science Signaling.

TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis

Hai-tao Xiao, Z. Bian, Na-Young Song, 2014, Scientific Reports.

TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4‐1BB and OX40

Jiaqiang Huang, T. Yoshimura, Xin Chen, 2011, European journal of immunology.

Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation.

Xin Chen, J. Oppenheim, O. Howard, 2004, Journal of alternative and complementary medicine.

Triptolide Attenuates Endotoxin- and Staphylococcal T-Cell Proliferation and Production of Cytokines and Chemokines

H. Young, Xin Chen, O. Howard, 2005 .

Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide

L. Wakefield, Xin Chen, J. Oppenheim, 2014, Oncoimmunology.

Fgl2 prothrombinase is involved in severe acute pancreatitis-associated liver injury.

Xin Chen, Zhiming Huang, X. Ye, 2012, Hepato-gastroenterology.

Therapy: Paradoxical effects of targeting TNF signalling in the treatment of autoimmunity

Xin Chen, J. Oppenheim, 2016, Nature Reviews Rheumatology.

Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity.

R. Salcedo, O. Chertov, J. Beutler, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.